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For the first time in more than a decade, a new treatment to improve brain function for Alzheimer’s disease has been submitted to the Food and Drug Administration (FDA) for review.This was after the drug trial was stopped and then a second look revealed some promising results.The Waterhouse family has seen the impact of Alzheimer’s firsthand.Gina and Steve Waterhouse have been a team most of their lives. They’ve been married for 43 years and ran several businesses together. Then in 2016, things started to change. Gina didn’t notice anything but employees at the family's businesses did.“I wasn't remembering some of the stuff I was supposed to be doing,” said Gina.Gina was diagnosed with early Alzheimer's disease that year.“They said, 'well you can come back in a year. We will check and see how you're doing, or we have a drug trial if you're interested,'” said Gina.Gina and Steve spent the next two and a half years at the Mayo Clinic, where Gina eventually got high doses of the drug aducanumab.Steve started to notice Gina was remembering more things and reported it back to doctors.“He just smiled and said, 'let me tell you what we're seeing. We're seeing cognitive improvement. And it’s the first time in my career.' These doctors said in their career that we've ever seen it,” said Steve.“He was so excited,” said Gina.Then in 2019, the drug trial suddenly ended. Gina says she felt like she’s gone downhill a little since it did.Rebecca Edelmeyer, PhD, with the Alzheimer’s Association, says the trial stopped early based on a futility analysis.“It was a statistical analysis that was done by the Biogen team, predicting that the trial would not actually be successful,” said Edelmeyer.Edelmeyer says then upon a second look at the trial data, they found that those people on the highest dose of the drug were seeing improvement in their brain function. She called it a very important moment for the Alzheimer’s research community.Now, the government will determine whether or not the drug is safe and effective enough to use.Steve mentioned there were some possible side effects like bleeding of the brain, but Gina did not experience any.Meanwhile, Gina can no longer take the drug. She and Steve have decided to retire.“We just decided tomorrow has to come today and we're having a great time. We're loving life,” said Gina.You can learn more about aducanumab here. 2394

Former prisoners are helping former prisoners break in to college courses.  The Urban Scholars Union is a relatively new organization created by ex-cons for ex-cons looking to better themselves through education. USU’s President Cesar Garcia said they started 18 months ago at San Diego City College to help “justice impacted” students succeed. “[We want to] empower them and motivate them to be productive members of society,” said Garcia. “We’re not monsters that they make us out to feel and make us out to be,” said San Diego City College student Ryan Rising. “We’re humans that made poor choices.” Rising spent 15 years behind bars for carjacking and attempted extortion but will matriculate to Cal Berkley on a scholarship after earning his Associate’s at City.“I’m super proud of myself,” he said. Garcia, who served seven years for a list of crimes, said the USU provides a space for former prisoners to get help, guidance, and support. The organization recently expanded to Southwestern College and is working on helping students at Mesa and Grossmont Colleges. USU also recently received its largest donation to date.  Current prisoners at Donovan Correctional in Otay Mesa donated ,000 to USU for scholarships and grants for former prisoners. “It just goes to show you how we do look out for each other,” said Garcia. “We just need go out and advocate to erase all these stigmas,” said Rising. 1470

Following the CDC's recent No Sail Order extension , cruise lines say they'll not only create a bubble, but they'll test everyone who steps onboard. The tourism industry has been hit hard by the pandemic, and industry leaders say people are ready to take their coronavirus precautions and set sail.“We’ve been out of California, we’ve done all the Mexican, Caribbean, Bahama, Alaska, Hawaii, we’re planning on Panama Canal next year. After that we want to go to Europe and do a riverboat cruise,” said Betsy Atwood, a passenger on 37 past cruises.When she's not "cruising,” Atwood calls Vassar, Michigan, home. She was onboard a ship last spring when cruise lines were ordered back home. Ever since then, she's been ready to get back out on the high seas.“They need to sail, they need to get them going. You’re safer on the ship then you are to the grocery store. They’re so clean to begin with and I know now they’re cleaner than they were before,” Atwood said.Cleaning is just one part of the broad plan to get passengers back said Joe Leon, vice president of field sales for Silversea in the Americas. Silversea in the Americas is the luxury arm of Royal Caribbean and its ships only carry 600 people on board, which is small by industry standards. Other vessels have capacities of five to six thousand guests.Leon said since the shutdown, they've been simulating what life would be like on the ship, including dining and egress.He said the team of experts behind "Healthy Sail Panel" detailed all of that in a 65-page report for the cruise industry.The "74-point memo on exactly what their recommendations are, assessment of our current protocols and how the science applies and why it should apply and why these are the recommended action and result is a safe environment, our idea is to create a bubble for customers,” Leon said.Testing 100% of passengers, face coverings, enhanced sanitation methods will be everywhere. Leon says the report details multiple focal points.“First is embarkation and screening,” Leon said. “That’s testing and how strict we are with crew and passengers and contractors. Then there's public safety on board and public access where you will have to wear masks and what’s the proper social distancing measures.”They're taking shore excursions into account too, and medical facilities. While things will be different, he says, it's everyone's responsibility to do their part so that everyone can safely sail when it's time.For Atwood, who has a new excursion planned for March, what they're doing is more than enough. She's part of a group who is anxiously awaiting their annual cruise, and says, “We’ll all be heartbroken; they need to open them back up," Awtood said.The CDC's No Sail Order expires October 31, but some cruise lines are postponing voyages through the end of 2020. 2823

Fifteen years ago today the lights went out on 50 million people in the Northeast—making it the largest power outage in US history.It happened on Aug. 14, 2003.  Wherever you were, the blackout seems like yesterday.On a warm, sunny day at around 4:10 p.m., power plants shut down in three minutes. The widespread power outage cascaded across eight Northeastern and Midwestern states and the Canadian province of Ontario.Life seemed to freeze as trains and elevators stopped. Everything, from cellular service to operations at hospitals and traffic at airports, was halted, as everyone waited for the power to turn back on.An investigation revealed that the start of the blackout could be traced back to an Ohio company, FirstEnergy.  771

For those wondering if “Jeopardy!” would go on after Alex Trebek’s death, Jeopardy producers confirmed on Monday that the show must go on.Jeopardy executive producer Mike Richards released a statement on Monday saying the show would resume production on November 30. The show will resume with Ken Jennings, a former contestant who was deemed the “Greatest of All Time” in January, as the first to guest host following Trebek’s death. Other guest hosts will be announced in the future.Jennings joined the program at the start of the current season as a consulting producer. Before winning the “Greatest of All Time” series in January, Jennings set a still-standing record of 74 wins in a row in 2004.“Alex believed in the importance of Jeopardy! and always said that he wanted the show to go on after him,” said Richards. “We will honor Alex’s legacy by continuing to produce the game he loved with smart contestants and challenging clues. By bringing in familiar guest hosts for the foreseeable future, our goal is to create a sense of community and continuity for our viewers.”Originally, Jeopardy! said it would have new episodes taped before Trebek's death through December 25. On Monday, the game show said that during the weeks of Dec. 21 and 28, Jeopardy! will air a top 10 of Trebek's past episodes. The final episode filmed before Trebek's death will air January 8. New episodes featuring Jennings will air starting January 11. "There will only ever be one Alex Trebek, but I'm honored to be helping Jeopardy! out with this in January," Jennings tweeted.Trebek died two weeks ago after being diagnosed with stage 4 pancreatic cancer. 1649