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WASHINGTON, Aug. 4 (Xinhua) -- U.S. scientists have found two gene mutations occurring in oligodendrogliomas, the second-most common form of brain cancer, according to a study to be published Friday in journal Science.For years scientists have been looking for the primary cancer genes involved in oligodendrogliomas evolvement. Scientists know the two chromosomes held the probable mutations, but the particular gene information remains unclear.Now scientists at Duke University Medical Center and Johns Hopkins University have discovered the most likely genetic mutations that researchers have been hunting for on chromosomes 1 and 19.The genes they identified, CIC or FUBP1, are tumor suppressor genes. The cancer-related pathways that involve these genes could become targets for future treatments, said Hai Yan, a Duke associate professor of pathology and co-corresponding author of the study.The researchers found CIC on chromosome 19 and FUBP1 on chromosome 1 based on an initial study of seven oligodendrogliomas. They found six mutations and two mutations, respectively, in the seven tumors. Further study of 27 more of these tumors showed that there were 12 and three mutations of CIC and FUBP1, respectively. The two genes were rarely mutated in other types of cancers, indicating that they are oligodendroglioma-specific genes.These genes were difficult to find until the technology improved, said Yan."The team used whole genome sequencing technology so that no genes would be excluded, and we found to our surprise that one gene, on chromosome 19, was mutated in six out of the seven initial tumor specimens we sequenced," Yan said. "A mutation frequency of 85 percent is very high."The finding of two additional new genes involved in oligodendrogliomas increases the chances for an effective combination drug therapy for the tumor, Yan said. He envisions a combination cocktail of drugs similar to the combination-drug treatments taken by HIV patients that would target different pathways involved in cancer, and assist both in reducing the chance of relapsing and increasing odds of success.

ROME, Sept. 27 (Xinhua) -- The 30th general assembly of the International Council for Science (ICSU) kicked off here on Tuesday to address key global challenges, featuring over 275 scientists and experts from all over the world.The goal of the four-day event, hosted for the first time in Rome by the National Research Center (CNR) as Italy's scientific member at ICSU, is to discuss how science can contribute to boosting sustainable development, fighting climate change, increasing well-being and health in the changing urban environment and tackling the side-effects of progress.At the official opening ceremony, CNR president Francesco Profumo stressed that scientific research was the key to solving all current crises."It's during times of crises that inventions, great strategies and discoveries are made," he said quoting Albert Einstein."Global cooperation is crucial in addressing society's needs. In the wake of the negative economic outlook we are witnessing research and technological transfer can turn into efficient instruments to guide countries towards a solid development giving us the tools to tackle with lucidity the great obstacles we face," observed Profumo.Appealing to both private and public institutions, Profumo thus urged to boost strategic partnerships between universities, governments and research centres."We must create a network of knowledge-sharing together with enterprises in order to multiply and better implement growth and well-being opportunities. But in order to do so concrete political decisions must be undertaken and financial resources are needed," he added.

ISLAMABAD, Sept. 11 (Xinhua) -- Chinese ambassador to Pakistan declared on Sunday that the Chinese government will provide an emergency humanitarian aid worth 30 million RMB (4.7 million U.S. dollars) to Pakistan to help its relief efforts.In light of the immense damages caused by the floods in some parts of Pakistan, Chinese Ambassador to Pakistan Liu Jian called on Pakistani Foreign Minister Hina Rabbani Khar on Sunday to express sympathy and solidarity of the Chinese people toward Pakistani people and declared that the Chinese government will provide the emergency humanitarian aid.Diplomats and staff of the Chinese Embassy in Islamabad have recently voluntarily donated 600,000 rupee (about 6860 U.S. dollars) to the people who hit by the floods. The Chinese ambassador handed over the donation to Pakistani side on Sept. 8.On Sept. 9, Chinese Foreign Minister Yang Jiechi sent a message to his Pakistani counterpart H.E. Hina Rabbani Khar, expressing his profound condolence to the victims and sincere sympathy to the affected people of the floods.The Chinese foreign minister said that China, as Pakistan's close friend, feels as much pain as Pakistan does and is ready to provide help to the best of its ability, in line with Pakistan's needs. He is convinced that the Pakistani people will definitely prevail over the natural disaster and rebuild their homes at an early date.

BEIJING, Sept. 20 (Xinhuanet)-- Google's executive chairman Eric Schmidt is to face a Senate hearing on whether the company is abusing its dominance in Internet search, according to media reports on Tuesday.At the Wednesday's hearing before the Senate Judiciary Committee's antitrust panel, Schmidt will argue that critics are wrong to say Google gives preference to its own products, instead, Google is just trying to deliver the best-cultivated search results for users. The issue of search ranking is a touchy subject with Google, which says its algorithm is devised to give users the most useful result so they will come back.Another focal point of the hearing, which Schmidt concerned most is "scrapers", those who game its search algorithm, for example, taking commonly searched words, combine them into a nonsensical block of text and throw it up on the Web to grab eyeballs and advertising dollars.Google believes that, if scrapers succeed too often, consumers will lose confidence in search and turn to other resources, thus posing an existential threat to the company.Regulators in the U.S. and abroad have been looking into various aspects of Google's business practices since the company's 2007 purchase of ad firm DoubleClick. At the moment, European regulators are conducting an antitrust inquiry into Google's search business while the Federal Trade Commission is doing likewise. Google relies overwhelmingly on its core product, Internet search, and dominates the market for that product. It handles around two-thirds of U.S. Internet searches and more than 80 percent in many European countries, according to comScore Inc.

CHICAGO, Aug. 25 (Xinhua) -- Gold futures on the COMEX Division of the New York Mercantile Exchange on Thursday bounced off the biggest drop since March 2008, as the weakness in stock market enhanced appeal of gold as a safe-have investment.The most active gold contract for Dec. delivery gained 5.9 U.S. dollars, or 0.3 percent, to 1,763.2 dollars per ounce. The metal suffered on Wednesday the biggest one-day drop since March 19, 2008.Market analysts said that gold extended losses in earlier trading, hit by a margin-requirement increase, but the drop in global stock market gave a push to the metal. Both Dow Jones industrial average and S&P 500 declined on Thursday after a 3-day rise as a government report showed U.S. jobless claims rose last week.Besides, market hearsay went that Germany might be next to get a sovereign-debt downgrade, adding to the positive tone on gold market. German equity market also suffered sharp drop in the day.Many market watchers remained long-term bullish attitude toward gold although they said the precious metal could correct further in the short term. A trader noted that the fundamental factors driving uncertainty and fears are all still there.Expectations are growing that the Federal Reserve Chairman Ben Bernanke would not provide any form of stimulus in a speech scheduled for Friday at a yearly gathering of central bankers in Jackson Hole.Silver for Sept. delivery also rose 1.583 dollars, or four percent, to 40.745 dollars per ounce. Platinum for Oct. delivery lost 3.9 dollars, or 0.2 percent, to 1822.4 dollars per ounce.