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INDIANAPOLIS — The U.S. Food and Drug Administration on Monday granted emergency use authorization to Eli Lilly and Company's experimental COVID-19 antibody treatment bamlanivimab.According to a statement from the company, the drug is authorized for the treatment of mild to moderate COVID-19 in adults and pediatric patients 12 years and older with a positive COVID-19 test who are at high risk for progressing to severe COVID-19 and/or hospitalization. Lilly said in a statement the drug should be administered as soon as possible after a positive COVID-19 test and within 10 days of symptom onset. The authorization allows for the distribution and emergency use of bamlanivimab, which is administered via a single intravenous infusion."This emergency authorization allows us to make bamlanivimab available as a COVID-19 treatment for recently diagnosed, high-risk patients — adding a valuable tool for doctors fighting the now-increasing burden of this global pandemic," David A. Ricks, Lilly's chairman and CEO, said. "The rapid development and availability of bamlanivimab could not have been achieved without the relentless work of our Lilly team, collaboration across the industry and the urgent work being done by the government to ensure appropriate allocation to patients who need it the most."The emergency use authorization is based on data from BLAZE-1, a randomized, double-blind, placebo-controlled Phase 2 study in patients with recently diagnosed mild to moderate COVID-19 in the outpatient setting. Patients treated with the drug showed reduced viral load and rates of symptoms and hospitalization, Lilly said in the statement. Infusion reactions and other allergic hypersensitivity events have been reported, Lilly said. The emergency use authorization includes a warning for hypersensitivity including anaphylaxis and infusion-related reactions.Lilly said the drug is not authorized for use in patients who are hospitalized due to COVID-19 or who require oxygen therapy due to COVID-19 or who require an increase in baseline oxygen flow rate due to COVID-19 in those on chronic oxygen therapy due to underlying non-COVID-19 related comorbidity."The BLAZE-1 data show bamlanivimab, when given early in the disease course, may help patients clear the virus and reduce COVID-related hospitalizations, supporting our belief that neutralizing antibodies can be an important therapeutic option for patients fighting this virus," Daniel Skovronsky, M.D., Ph.D., Lilly's chief scientific officer and president of Lilly Research Laboratories, said. "We're proud of the speed with which we have been able to bring patients this therapy specifically designed to treat COVID-19. We thank those who have contributed to this medical advancement, particularly the clinical trial investigators and participants around the country." This article was written by Bob Blake for WRTV. 2906

The Lifetime channel has cast its first LGBTQ+ Christmas romance movie, set in Milwaukee, this winter. The movie will star real-life same-sex married couple Ben Lewis and Blake Lee in the upcoming film “The Christmas Set Up,” which premieres on Lifetime Dec. 12.“The Christmas Set Up” follows Hugo (Lewis), a New York lawyer, and his best friend as Hugo spends the holidays in Milwaukee with his matchmaking mom, Kate.When Kate sets Hugo up with Patrick (Lee), Hugo’s high school friend and secret crush, there is an undeniable, mutual attraction between the two.But when Hugo receives news of a job promotion in London, he must choose what is most important to him.“Diversity and inclusion is a top priority for us,” a Hallmark Channel spokesperson said in a statement, per Good Morning America. “We are committed to creating a Hallmark experience where everyone feels welcome.”Report a typo or error // Submit a news tip This story originally reported by Patricia McKnight on tmj4.com. 1011

At the age of 22, Purdue University graduate Andrew Hoyler accomplished his goal of becoming a pilot. But in doing so, his debt took off. He took on 4,000 in student loan debt. “It was tough to look forward to the future, just because 4,000 clouding over your head is not something that anyone wants,” he says. As a new pilot, he brings less than ,000 a month after taxes. Yet, less than two years after he graduated, he's been able to pay off more ,000. “Looking back, it's crazy that it's already come this far and that I’ve been able to pay off this much, but it hasn't been without sacrifice,” Hoyler says. Those sacrifices include living at home with parents, skipping out on vacations with friends and using a large chunk of a ,000 signing bonus to pay down his debt.“It was a little rough putting most of that towards the student loans,” he says. “But here today, I'm happy I made that decision and didn't go out and buy a new car.” Hoyler says he also uses his tax refunds to help pay down his debt. It's something anyone who gets a refund can do, whether it's for student loans, car payments or credit cards. “For many Americans, the biggest windfall they get all year is a tax refund, so this time of year, that is a great opportunity to really take out a big chunk of your debt,” says Arielle Oshea, a personal finance expert with NerdWallet. Oshea says for Americans struggling with debt, taking small steps like cutting cable, skipping eating out or not going shopping can add up.“Small amounts seem like they're going to be a drop in the bucket compared to your debt balance in many cases. But when you add them together and you make a cut here and make a cut there, and you maybe bring in some extra income, all of that adds up and it can very quickly lead to you being able to make bigger payments on your debt every month,” Oshea says. As Hoyler proves, small sacrifices can lead to a big payoff. 1940

As the holiday season approaches, organizers for the Times Square New Year’s Eve celebration said this year’s festivities will be “virtually enhanced” and very different.This year, the celebration will bring Times Square and The Ball to the audience digitally, no matter where they are.A scaled back and socially distanced live production is still being determined."People all over the globe are ready to join New Yorkers in welcoming in the new year with the iconic Ball Drop. I commend the Times Square Alliance, Jamestown Properties, and Countdown Entertainment on finding a safe, creative and innovative way for all of us to continue to celebrate this century old-tradition. A new year means a fresh start, and we’re excited to celebrate,” said Mayor Bill de Blasio.“One thing that will never change is the ticking of time and the arrival of a New Year at midnight on December 31st,” said Tim Tompkins, President of the Times Square Alliance, which co-produces the event with Countdown Entertainment.“Because any opportunity to be live in Times Square will be pre-determined and extremely limited due to COVID-19 restrictions, there will be the opportunity to participate virtually wherever you are. Because more than ever in these divided and fear-filled times, the world desperately needs to come together symbolically and virtually to celebrate the people and things we love and to look forward with a sense of renewal and new beginnings,” Tompkins added.Due to the ongoing coronavirus pandemic, many events have been canceled or modified to fight the spread of the virus. The New Year’s Eve Times Square ball drop, which typically brings millions of people together in Manhattan, is no different.Earlier this month, the mayor and Macy's announced the annual Thanksgiving Day Parade will be "reinvented" with virtual aspects. The Macy's Fourth of July fireworks were also modified into smaller fireworks displayed before a grand show was aired on television. This story originally reported y Kristine Garcia on PIX11.com. 2053

I’ve been reluctant to put my feelings into words. My brain refuses to accept that both Kobe and Gigi are gone. I can’t process both at the same time. It’s like I’m trying to process Kobe being gone but my body refuses to accept my Gigi will never come back to me. It feels wrong. Why should I be able to wake up another day when my baby girl isn’t being able to have that opportunity?! I’m so mad. She had so much life to live. Then I realize I need to be strong and be here for my 3 daughters. Mad I’m not with Kobe and Gigi but thankful I’m here with Natalia, Bianka and Capri. I know what I’m feeling is normal. It’s part of the grieving process. I just wanted to share in case there’s anyone out there that’s experienced a loss like this. God I wish they were here and this nightmare would be over. Praying for all of the victims of this horrible tragedy. Please continue to pray for all. 909