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SAN DIEGO (KGTV) — UC San Diego Health and three other UC Health medical centers will begin to recruit participants for an antiviral drug being tested to treat the novel coronavirus.The medical system will start "phase II" clinical trials for the antiviral drug remdesivir. The drug has "shown activity in animal models and human clinical trials of SARS-CoV, MERS-CoV, Ebola, Marburg and other viruses," according to UCSD Health.RELATED: San Diego hospitals start drives for personal protective equipmentRemdesivir is not currently approved for the treatment of any infection by the FDA, but is currently undergoing trials for treating multiple viruses, including COVID-19.“With this type of adaptive study design, if remdesivir proves to be safe and active, the clinical trial may be rapidly adapted to remove the requirement for a placebo arm and add a treatment arm that includes other promising antiviral or other investigational drug to compare with the activity of remdesivir," said co-principal investigator Constance Benson, professor of medicine at UC San Diego School of Medicine and an infectious disease specialist at UC San Diego Health.RELATED: Nurse urges people to turn over N95 masks to San Diego hospitalsUC San Francisco, UC Irvine Health, and UC Davis Health are also participating in the trials. The trial is projected to run until April 1, 2023 and involve 440 participants. 1404

SAN DIEGO (KGTV) - Whether you're looking to eat, drink, or stroll around San Diego this weekend, there's an event just for you.Mission Beach will celebrate is delicious culinary scene Thursday in its annual Taste of Mission Beach event, benefiting clean beaches.Still hungry? San Diego Taco Fest heads to town Saturday for some delicious fun, live music, and Lucha Libre action in Waterfront Park.Don't see anything interesting? Check our 10News event calendar for even more local happenings!Pirates will take over the San Diego Maritime Museum for a two-day celebration of the seven seas, and cowboys and cowgirls will saddle up in Ramona for some rodeo fun:THURSDAY5th Annual Taste of Mission BeachWhere: Various restaurants; Cost: Mission Beach invites foodies to walk, ride, or sail to as many Mission Beach restaurants and sample their delicious eats during Taste of Mission Beach. Proceeds from the event benefit the Pacific Beach Street Guardians, which works to keep beach communities clean. Encinitas Cruise NightsWhere: Downtown Encinitas; Cost: FreeDowntown Encinitas will be hopping with the sounds of rock n' roll against a backdrop of muscle, hot rod, and classic cars from D St. to K St. Check out historic vehicles from local owners, enjoy live music, and stick around to see whose rides win some awards or grab some dinner on Highway 101. 1397

SAN DIEGO (KGTV) — With the threat of yet another rollback for San Diego businesses, owners are concerned. San Diego County is on track to move into the most restrictive tier, meaning restaurants, personal care shops like nail salons, museums, zoos, places of worship, movie theaters, and gyms all have to operate completely outside. The county is expected to announce that rollback Tuesday, Sept. 22.Ricardo Zarate Jr is the Director of Operations for Leucadia Company, a group that manages three Encinitas restaurants, including Valentina and Moto Deli. He said they’ve been trying to adapt with the times, adding trees and decorations to their outdoor dining, but hearing the news that the community is moving in the wrong direction is hard.RELATED: What happens if San Diego County moves to California's most restrictive tier“You think ‘okay we’re doing our due diligence, we’re making steps, there’s progress,’ and then to find out there’s not going to be that progress and in fact there might even be some regress, it’s disheartening,” said Zarate.He said he anticipates more restaurants will likely permanently close if they have to shift to outdoor yet again. When asked about the roller coaster of opening and closing, he said his restaurants will make it, but knows it’s hard on others.“On one hand it would be nice to not be wondering when the next step back is going to come but on the other hand, I can see how some of our fellow restaurants do benefit, even if it’s briefly, from being able to open up their indoors,” he said.Jessica Huynh at Bella Paris Nails in Little Italy knows the benefits of being able to open indoors. Her nail salon does not have the space to open outside, so they stayed closed the whole pandemic. After almost six months of no business, they finally reopened when indoor services were allowed in September. Now, less than three weeks later, they’re faced with the possibility of only outdoor services again, which for them means another closure.“I don’t know if we can work outside, so maybe we close again,” said Huynh. 2070

SAN DIEGO (KGTV) — Two people working on scaffolding on the side of a downtown high-rise were rescued Tuesday after their equipment became stuck.The two workers were stuck 42 stories in the air after their equipment failed just before 10 a.m., leaving their mobile scaffolding stuck, according to San Diego Fire-Rescue.Fire crews climbed to the top floor 46 stories up and were lowered down to the trapped pair. Glass on the 43rd floor of the building was then removed and the workers were hoisted into the building. View this post on Instagram SD Fire-Rescue crews are on scene at a building under construction at 14th and Island. SDFD dispatchers received the request for assistance at about 9:50 Tuesday morning. Two construction workers were on a window washing lift when the lift stopped functioning and the workers were not able to move the lift. USAR 2, engines 2 and 4 and trucks 1 and 11 along with medic 10 responded. The technical rescue team went to the roof and set up the rope system. They lowered down to the construction crew outside the 42nd floor and were able to remove a window on the 43rd floor. The 43rd floor window served as the extraction point. The first construction worker was rescued at 10:52 and the second at 11:01 a.m. The firefighters are now in the process of retrieving their rescue equipment. No injuries. Excellent teamwork and coordination on this incident. #sdfd #sandiego #technicalrescue #rescue #trt #firefighter #paramedic #highrise #commitment #excellence #training @joinsdfd #pride A post shared by San Diego Fire-Rescue (@sandiegofiredept) on Jun 4, 2019 at 11:10am PDT Neither worker was injured. The two workers were performing welding work on the building.SDFD Battalion Chief Brian Raimes said weather was in their favor during the rescue and that the building was unoccupied, making the rescue easier.A park below was temporarily evacuated in case anything fell from the high-rise. The building, located at 14th St. and Island Ave., is one of the tallest buildings in downtown, Raimes added. 2069

SAN DIEGO (KGTV) - UC San Diego School of Medicine researchers believe they have discovered a way to reduce what they describe as health risks associated with red meat. A study published Monday in the journal Nature Microbiology considers whether bacterial enzymes could be used to clear from our tissues a carbohydrate created when humans eat red meat. The carbohydrate, known as Neu5Gc, builds up as we eat red meat, researchers say. They suggest our immune systems treat Neu5Gc as a foreign invader and generate antibodies against it, leading to chronic inflammation and other diseases. A team led by UC San Diego professor of pediatrics and bioengineering Karsten Zengler, Ph.D., believes bacterial enzymes could remove Neu5Gc from red meat before people eat it. “It’s our hope that this approach could be used as a sort of probiotic or prebiotic to help reduce inflammation and the risk of inflammatory diseases - without giving up steak,” said Zengler. The researchers bought steak and pork sausage from a grocery store and rubbed it with a lab-made bacterial enzyme. They found that “sure enough, most of the Neu5Gc came right off,” according to UC San Diego officials. Zengler and his team are working to optimize the enzyme to make sure it removes Neu5Gc and not similar carbohydrates. The group will also explore mass production possibilities and the potential for preventing inflammation and inflammatory diseases.The study was funded by the National Institutes of Health, National Science Foundation, UC San Diego Chancellor’s Research Excellence Scholarship, and Science Without Borders, officials said. 1624

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