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2025-06-02 11:37:38
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Moderna announced Thursday they have started giving teenagers their COVID-19 vaccine as part of their study on how the vaccine works in those under 18.Pfizer, the other vaccine maker with an emergency use request for their COVID-19 vaccine in adults before the FDA, started including teens in their trial in October.In the Moderna’s press release, they say the Phase 2/3 study of the mRNA vaccine is now underway and is being conducted on children between the ages of 12 and 18.“We are pleased to begin this Phase 2/3 study of mRNA-1273 in healthy adolescents in the U.S. Our goal is to generate data in the spring of 2021 that will support the use of mRNA-1273 in adolescents in advance of the 2021 school year,” said Stéphane Bancel, Chief Executive Officer of Moderna in a company statement. “We hope we will be able to provide a safe vaccine to provide protection to adolescents so they can return to school in a normal setting.”The Phase 2/3 study from Moderna is being done to test the safety and immunogenicity of the two-dose vaccine they submitted to the FDA for emergency use approval last month.They plan to enroll about 3,000 teenagers in the U.S. in the trial, with each receiving either a placebo or the vaccine in two doses, 28 days apart. 1262

  濮阳东方医院治疗早泄很便宜   

Neanderthals may not have been that different from us, after all.New evidence reveals that they created the world's oldest known cave paintings and even wore seashells as body ornaments. Both behaviors suggest that they thought symbolically and had an artistic sensibility like modern humans. Two studies published Thursday in the journal Science detail the latest findings."Undoubtedly it is showing that Neanderthals were thinking and behaving just like modern humans," Alistair Pike, co-author of the studies and professor of archaeological sciences at the University of Southampton, wrote in an email."We should no longer think of them as a different species, just humans in different places," he said.The new findings of symbolic thinking show that Neanderthals and modern humans were cognitively indistinguishable, the researchers said.Cave paintings and artifacts like painted seashells have long been regarded as the work of early modern humans, who were thought to have more advanced cognitive abilities than Neanderthals. Dating cave paintings can be a difficult process, and unreliable techniques never allowed for the possibility that these could be the work of Neanderthals.Until now, that is. A new technique called Uranium-Thorium dating is less destructive, is more accurate and can go back further in time than other methods. U-Th dating looks at the deposits of carbonate on top of the paint, which contain traces of uranium and thorium that indicate when those deposits formed. That allows the researchers to determine an age for what's under the deposits.The researchers applied this technique to paintings in the La Pasiega, Maltravieso and Ardales caves in Spain, which had never received "robust" dating. The paintings include red and black images of animals, dots, lines, disks and other geometric signs. There also are engravings, hand prints and hand stencils.Those hand stencils are particularly significant, and not just because they represent the hand size of a Neanderthal."A red line, a red dot or even a positive hand print could potentially be made 'accidentally,' " wrote Dirk Hoffmann, lead author of the studies and archaeologist with the Max Planck Institute for Evolutionary Anthropology, in an email."Of course, I am sure that this is not the case, since you would still need to bring [in] light and pigment, but one could argue that all you need is some pigment on your hand when you lean against a wall. A hand stencil cannot be explained like that. You have to hold your hand against the wall and the deliberately spray pigment over this. This is why we emphasize the hand stencil."The dating revealed that the cave art was created more than 64,000 years ago -- 20,000 years before modern humans appeared in what is now considered Europe.The shells were found in the Cueva de los Aviones, a sea cave in southeastern Spain. They are unique because they are perforated with holes and colored with red and yellow pigment. Others served as containers for the mineral pigments themselves. The pigments were used on the shells but could have also been used for the cave paintings and even as body paint.The deposit layer containing the shells dated to 115,000 years ago, which is even older than other shells recovered in Africa that were dated to modern humans."The standard archaeological interpretation of such finds is that they are body ornaments," Hoffmann said. "Similar finds were made in Africa or the Levant with similar age. In Africa or the Levant, these were made by modern humans, in Spain Neanderthals made them. So in terms of symbolism, early modern humans and Neanderthals were similar."The researchers are absolutely confident in their dating technique."We have spent 10 years refining the technique and have numerous quality controls," Pike said. "The dates respect the growth axis of the deposits we are dating, the oldest closest to the painting, the youngest at the surface."Once modern humans left Africa and migrated to Europe and other areas, mixing with the Neanderthals would've been inevitable. The researchers believe that the Neanderthals created this artwork on their own, without being influenced by any other population. But it's possible that they exchanged symbolism or that Neanderthals influenced the art and symbolism of modern humans. Modern humans were capable of symbolic behavior, so it "turns the who's copying who debate on its head," Pike said."The idea that culture only evolved with modern humans no longer makes sense," Pike said. Hoffmann suggested that Neanderthals now be referred to as "very close cousins" of modern humans.Is it possible that anyone else may have created the cave paintings?Pike said it is incredibly doubtful that a population of early modern humans migrated to Europe so early without any other evidence to suggest it."We cannot of course rule out that pre-Neanderthal populations made the art," Pike said. "This sounds like a project for the future."Hoffmann, Pike and their colleagues want to use their new dating technique in more caves in Spain, as well as France and Italy -- and anywhere else Neanderthals are known to lived.The findings also raise new questions for researchers."How far back does symbolic behavior go? Can it be traced to the last common ancestor of modern humans and Neanderthals? This is perhaps where we should be looking," Pike said. 5398

  濮阳东方医院治疗早泄很便宜   

More than 230,000 institutions around the world now have free access to a new tech tool that focuses on social and emotional learning during a time when people need human connection more than ever.Like most teachers around the country, Rory Yakubov did not get the type of "back to school" that she was hoping for.“You have to go with the flow, really, if you’re going to stay on top of things right now,” Yakubov said. “Having a mindset where I’m going to have everything perfect is not going to happen. I’m OK - I’m getting OK with that.”Yakubov says her New Jersey district started the school year remotely, which meant the high school math teacher had to figure out how to connect with her students virtually.“It would be so nice if I could walk around the classroom with my students, engage them, check in, have conversations about how they’re doing also have personal conversations with my students,” Yakubov said.Yakubov and her district use Microsoft Teams. She teaches algebra 1 and geometry through the platform, and says she's really looking forward to some new features within Teams. She views it as another tool in her toolbox.Microsoft's education director Mark Sparvell says the roll out includes "praise badges," which are cute, colorful and eye-catching stickers for teachers to "hand out" to their students.“What these tools do is they provide an avenue even when we’re between glass to allow young people to be seen, heard and know they matter,” says Sparvell.Things like reflections and emotional check-ins are also new, and they come at a time when students everywhere are more stressed and anxious than ever.“How is a student feeling, how is my class feeling, how is my school feeling, how is my district feeling,” Sparvell said.Years of research and development led them to this point, says Sparvell. The new tools are based off of science to help youth development. He says these sorts of social and emotional connections are critical for every student.“They’re tied directly to academic outcomes, to positive life outcomes, to mental health and physical health and they’re tied to potential to be employed and remain employed in the future,” Sparvell said.Yakubov says she hopes it'll force her high schoolers to engage, as teens often have a tendency to withdraw.“I am here for them,” Yakubov said. “I want them to succeed and it’s really tough. I would be able to go over to that student who’s super quiet and nudge them and have a quiet conversation and I can’t do that now and I don’t even know who those students are yet and I’ve been teaching five weeks.”She also says, for those teachers how are struggling to help students succeed, this is one way to help guide everyone along, in what may just be their toughest year. 2759

  

MSNBC host Joy Reid this week employed the same excuse as so many other public figures who have been embarrassed by something they had written online: she said she was hacked.But after widespread skepticism regarding her claims, Reid and her employer went further than most of those humiliated celebrities, providing analysis from her own cybersecurity consultant, who said that old, homophobic posts that appeared to have been published on Reid's now-shuttered blog were indeed the result of nefarious activity.Reid, a liberal pundit who hosts a program every weekend on MSNBC, said Monday that a number of posts unearthed by a Twitter user were placed online by an "external party."The claim was met with immediate and widespread skepticism; the doubt shifted to derision on Tuesday afternoon, when a representative for the Wayback Machine, a digital archive that stores old content, said that a review "found nothing to indicate tampering or hacking of the Wayback Machine versions."The backlash grew so severe that an LGBTQ advocacy group, PFLAG National, announced that it was rescinding an award it intended to give to Reid next month.But on Tuesday night, a spokeswoman for MSNBC shared several documents with CNNMoney, including a statement from an independent security consultant named Jonathan Nichols, who said he has "significant evidence" that some of the recently circulated posts are bogus.In his statement, Nichols said that he "discovered that login information used to access the blog was available on the Dark Web and that fraudulent entries -- featuring offensive statements -- were entered with suspicious formatting and time stamps.""At no time has Ms. Reid claimed that the Wayback Machine was hacked, though early in our investigation, we were made aware of a breach at archive.org which may have correlated with the fraudulent blog posts we observed on their website," Nichols said. "We simply wanted to ascertain whether that breach was related to the compromising of Ms. Reid's blog."He pointed out that the inflammatory blog entries in question didn't have reader comments. "If those posts were real, they would have undoubtedly elicited responses from Ms. Reid's base," he wrote.The MSNBC spokesperson also provided letters sent in December from Reid's attorney to Alphabet, the parent company of Google, which owned the site on which Reid's blog was hosted at the time of the disputed posts, and Internet Archive, which runs the Wayback Machine, to alert the companies of the alleged hacking. CNNMoney has reached out to Alphabet for comment. The MSNBC spokesperson did not respond to a follow-up inquiry regarding Alphabet's response.Nichols said that many of the posts in question were published at a time when Reid was hosting a radio show, and that the "text and visual styling was inconsistent with her original entries."He added that "some of the recently circulated posts were not even on the site at any time, suggesting that these instances may be the result of screenshot manipulation."Reid's attorney, John H. Reichman, highlighted what he said was another discrepancy in his letters to the companies, pointing out that Reid published posts on January 10, 2006 about the confirmation hearings for Supreme Court Justice Samuel Alito at 10:18 a.m., 11:34 a.m. and 11:41 a.m., but that the archive showed what Reichman described as a "lengthy, fraudulent entry" at 11:28 a.m."Ms. Reid did not have the superhuman blogging skills needed to do all of these posts simultaneously," Reichman wrote.A Library of Congress archive of the site shows that the "lengthy" entry contains only two sentences of text actually written by the post's author; the rest is a quote.The Library of Congress archive reviewed by CNNMoney -- which the Library says is created using a local installation of the Wayback Machine -- contains the disputed posts and lists them as having been archived on January 12, 2006. The documents provided by MSNBC to CNNMoney do not contain a letter to the Library of Congress regarding its archive.In his letter to Internet Archive, Reichman demanded that the site provide "the information needed to determine how the fraudulent posts came to be included in the archived posts." He asked Alphabet for "immediate assistance in determining how, when and by whom the Blog was hacked and the fraudulent posts entered."The controversy, one of the strangest in recent memory to ensnare a media personality, began Monday, when Mediaite reported on the blog posts, many of which contained homophobic sentiments. In one, the author wrote "most straight people cringe at the sight of two men kissing," and that it is in the "intrinsic nature" of straight people to find homosexual sex "gross."Reid told Mediaite in a statement that she "began working with a cyber-security expert who first identified the unauthorized activity," and that she "notified federal law enforcement officials of the breach."The claim was met with plenty of skepticism, at least in part because Reid had already apologized in December for other years-old anti-gay posts that appeared on the blog, which were found by the same Twitter user, @Jamie_Maz, who also unearthed this week's posts through the Wayback Machine.It didn't help Reid's credibility when the representative for the Wayback Machine rebutted her claim on Tuesday afternoon."When we reviewed the archives, we found nothing to indicate tampering or hacking of the Wayback Machine versions," wrote Chris Butler on the Wayback Machine's blog. "At least some of the examples of allegedly fraudulent posts provided to us had been archived at different dates and by different entities."Butler said "the point at which the manipulation is to have occurred, according to Reid, is still unclear to us," and that he and his colleagues "let Reid's lawyers know that the information provided was not sufficient for us to verify claims of manipulation.""Consequently, and due to Reid's being a journalist (a very high-profile one, at that) and the journalistic nature of the blog archives, we declined to take down the archives," Butler wrote. "We were clear that we would welcome and consider any further information that they could provide us to support their claims."  6251

  

NASHVILLE, Tennessee — Individuals convicted of a felony can't vote while incarcerated, on parole, or on probation in the State of Tennessee, and Terrancé Akins was one of those people — until this week.Akins will get to vote for the first time after serving 17 years in prison.When he was 17-years-old, Akins went to prison for especially aggravated robbery."I lost my family, I lost my freedom, and then I lost my right to vote," Akins said.He has started a non-profit called 'Blessed Incorporated' where he helps inner city kids stay out of trouble. It took four years, but now that he is on a steady path, he's excited to be able to vote for the first time. "It feels great. It feels wonderful," he said.In Tennessee, voting rights are restored when ex-felons complete their supervised release. Akins hopes his example will help encourage others to re-register to vote. "They give up on themselves, they give up on their lives, they figure that they can never really amount to anything, but that's not true. You have to believe in yourself and you have to believe that you matter and that your vote matter, and that's one thing that I did, I took the initiative to not just do this for me, but to do it for those that are coming behind me," said Akins.The voter registration deadline is on Tuesday, you can fill out a form online or sign up in person.Akins is now renting an apartment in Montgomery County. Early voting there starts Oct. 17 and runs through Nov. 1. Election Day is Tuesday, Nov. 6. 1575

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