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Their youthful brains were developing normally, with no signs of developmental, psychological or neurological problems. None had ever had a concussion. But by the end of a single football season, 24 children between the ages of 9 and 18 who had more frequent impacts to the head showed signs of damage to brain development, new research says."Repetitive head impact exposure may have a cumulative effect in the rapidly developing brains of youth and high school football players," said study co-author Gowtham Krishnan Murugesan, a radiology research assistant at UT Southwestern Medical Center in Dallas, adding that the results mirror other recent findings.The study outfitted 60 youth and high school football players who had no history of head trauma or developmental issues with a head impact telemetry system that measures the magnitude, location and direction of impacts to the head. The researchers were not looking at whether the impact resulted in a concussion, only that impact occurred.The children were sorted into two categories: high cumulative head impact players (24) and low cumulative head impact players (36).Before beginning to play, each child had a resting state functional scan, known as an fMRI; the scans were repeated at the end of football season. The researchers were trying to see how exposure to repetitive hits affects the normal "pruning" process in the brain that occurs during adolescence."Pruning is an essential part of brain development," Murugesan said, comparing the process to how a tree needs to have dead or unneeded branches cut to keep it healthy and allow it to grow."Disruption in normal pruning has been shown to be related to weaker connections between different parts of the brain," he said.After comparing the functional MRI results to the player's level of impact, the researchers found that youth in the high-impact group had damage to their brains' pruning process after one season."Our study has found a significant decrease in gray matter pruning in the frontal default mode network, which is involved in higher cognitive functions, such as the planning and controlling of social behaviors, " Murugesan said.Although the "teenage years are a critical time for brain development, brain remodeling or synaptic pruning, this was a short-term study and did not follow the players longitudinally over several years. We don't really know the full application," said Dr. Julian Bailes, director of neurosurgery and co-director of the NorthShore University HealthSystem Neurological Institute, who was not involved in the research.Weill Cornell neurologist Dr. Richard Isaacson, who was also not involved in the study, called the research "early" and said the results don't necessarily "translate to a clinical or cognitive outcome." More research is needed to see whether the decline in brain pruning permanently affected the child's cognitive function or whether the brain's natural plasticity allowed it to repair itself."I would call this a pilot study," Isaacson said. "The call to action would be that we need more robust longitudinal studies with a pre- and a post-assessment of more than brain imaging. The study should also measure cognitive and neurological function and look for changes."As we learn more about the issue, Isaacson said, parents should do everything they can to limit contact in sports, "especially in practice before games, where studies show the majority of contact occurs." 3464

Tide laundry detergent will soon be shipped in a shoe box, part of its parent company Procter & Gamble's push to adapt to online deliveries.P&G rolled out the new "Tide Eco-Box" on Friday. It features a twist-to-open pour for the detergent, a pull-out stand, and a measuring cup. The liquid formula, which contains less water than normal Tide, comes in a sealed bag.The version uses 60 percent less plastic than shipping an equivalent 150-ounce bottle of Tide since it doesn't require additional layers of cardboard boxing or bubble wrap. It's lighter and takes up less space in a delivery truck—saving P&G money on shipping costs."Its size is perfect for the e-commerce supply chain," said David Luttenberger, global packaging director at market research firm Mintel. "It's an easy package for nearly any consumer to pick it up, manipulate the opening features, and dispense from."Tide Eco-Box will join Tide's lineup on Amazon (AMZN), Walmart's website (WMT) and other P&G (PG) retail partners' sites starting in January. 1047

Tinder is soaring thanks to its new premium membership plan: Tinder Gold.Match Group, which owns 45 dating platforms including Tinder, OkCupid and Match.com, reported on Tuesday that Tinder Gold subscriptions boosted sales 19% from a year ago.Tinder added a record 476,000 paying members last quarter. Now 2.5 million customers pay for Tinder.Match CEO Greg Blatt called Tinder's quarter "fantastic" in a prepared statement.Investors swiped right on the report: Shares of Match Group spiked 11% on Wednesday. The stock is up 75% this year.Tinder already had Tinder Plus, which costs .99 a month and allowed customers to increase the number of people who viewed their profiles, use unlimited likes and undo swipes.In August, Tinder debuted Tinder Gold, a .99 monthly subscription that lets customers see who they've matched with as soon as they open the app. Tinder Gold saves time on the app because people don't have to swipe through other profiles to find matches."Tinder Gold plays on people's impatience," says BTIG analyst Brandon Ross.Ross says Match Group has mastered how to make money off loyal Tinder users."They're proving that if you have a deeply engaged base you will eventually get them to spend money," he explained.Still, Match Group faces competition from other dating apps like Bumble, Tastebuds, Hinge and Coffee Meets Bagel and will need to show investors that it's adding new paid subscribers.But analysts are convinced Tinder has room to grow and convert more customers to its paid offerings."There's a lot of momentum that remains behind the broader Tinder story," says Piper Jaffray analyst Sam Kemp.  1646

There’s a major love affair in the U.S. between humans and their furry friends. A playful puppy named Clifford has been Rachael Greenberg’s saving grace during the pandemic. She says the past nine months have brought a lot of anxiety into her life, but Clifford’s relentless support helped her through the first panic attack she ever experienced.“He woke up, and just like kind of climbed on my lap and he tried to put my feet up. And I don’t think he knew exactly what was going on, but he just like seemed to respond to it,” Greenberg said.Greenberg isn’t alone in her feelings.There’s been a rise in depression and anxiety in many people’s lives since the start of the pandemic.It’s Samara’s job as a therapy dog to offer people love and support.“She went and met one of the students who was quarantined due to COVID-19 who was feeling a little down and lonely,” human-animal connection expert Philip Tedeschi said.Tedeschi is a professor in the graduate school of social work at the University of Denver, and a human-animal connection expert with the dog-sitting website Rover.“We’re looking at human-animal connection through the lens of how people and animals interact and what some of the health-promoting benefits of that are,” Tedeschi said.According to a recent survey done by Rover, 92% of dog owners say that their dog has played a role in positively impacting their mental health since the pandemic began. Tedeschi says history proves dogs have become some our most important, reliable and trusting friends.“Some people would argue that we may have been co-evolving with dogs for 20-to-60-thousand years or more, and what has occurred as a result as that is dogs have become especially attune to people, and people have become specially attune to dogs.”Tedeschi says we can measure how our interactions with companion animals influence our health. In fact, he says humans can tend to match their own breathing and heartbeat to the resting rate of an adult dog which helps us to calm down.“They understand our language, they know the nuances of the tone of voice we use, in many cases they’ll recognize something as small as a millimeter of movement in the human face that reflects a change in our emotion,” Tedeschi said.There’s a reason dogs are used to comfort veterans with PTSD and patients in hospitals. They offer endless love and keep us present in the moment.“It turns out that social support doesn’t only have to be human beings that support us," Tedeschi said. "That in many cases our non-human animal relationships are really effective support systems for us.”It was Greenberg’s time in a hospital that inspired her to study social work and animal therapy.“I have an auto-immune disease that I was diagnosed with at nine years old," Greenberg said. "We had a dog named Teddy and specifically got him when I was diagnosed.”Now she’s training Clifford to be a therapy dog. He’s brought happiness to her grandmother who lives with dementia. Greenberg says she’ll be a dog owner for life. 3016

Those who know me know that there are few things that get me more fired up than protecting the Postal Service!#DontMessWithUSPS— Senator Tom Carper (@SenatorCarper) August 21, 2020 188