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LOS ANGELES, July 18 (Xinhua) -- At least 70 genetic mutations may be involved in the formation of colon cancer, far more than scientists previously thought, a new study suggests.The study by researchers at University of Texas (UT) Southwestern Medical Center contradicts previous thinking that only a few mutated genes may play a role in the development of colon cancer."The ways we've been treating patients up to now is to just go after one target when we should be going after three to four different pathways simultaneously," said Dr. Jerry W. Shay, vice chairman and professor of cell biology at UT Southwestern.The new study identified 65 candidate genes and at least five passenger genes whose mutations play significant roles in cancer development. Inactivating the function of any of these tumor- suppressing genes led to a key step in cancer development called anchorage-independent growth, meaning cells piled up on top of each other rather than aligning neatly.According to previous studies, there were 151 candidate genes and that mutations in just eight to 15 of them would lead to cancer. There were 700 other genes classified as passenger genes whose mutations were incidental to cancer growth.Current cancer treatments target just one or two known cancer- driver genes. While patients may get transient tumor burden reduction, almost universally tumor growth returns."Those numbers are dead wrong," Dr. Shay said, suggesting a new approach to colon cancer treatments targeting multiple genes and pathways simultaneously.The next step is further research to classify more accurately which genes drive cancer and which are merely passengers, the researchers said.Study findings were published in the July 2011 Cancer Research (Priority Reports).

UNITED NATIONS, Sept. 19 (Xinhua) -- As the UN on Monday pursued the world's top killer -- non-communicable diseases (NCDs) -- a leading doctor from the World Health Organization (WHO) called for preventative measures on such chronic diseases to be placed higher on the international agenda."It's not a choice of dealing with it or not, it's an absolute fundamental imperative for development," said Dr. Douglas Bettcher, WHO's director for the Tobacco Free Initiative, told Xinhua in a recent telephone interview.With NCDs already claiming 36 million lives a year -- nearly 100,000 people a day -- the UN Geneva-based health agency, WHO warns that deaths from chronic diseases will continue to climb even faster, amounting to 52 million deaths by 2030.As world leaders on Monday kicked off a two-day high-level meeting to enact a roadmap to attack diseases like cancer, diabetes, heart and lung diseases, it is hoped that the summit on NCDs, which is being called a "once in a generation opportunity," moves to become a "worldwide priority," Bettcher said.Marking the second time in its history that the United Nations General Assembly has ever put a global disease on the table, health experts and world leaders from 193 nations met to avert what the UN has declared a "public health emergency in slow motion. ""It's a make it or break it time for moving forward this very important agenda at this time of global financial crisis," said Bettcher.Calling NCDs the top global killer "by a long shot," Bettcher attributed such rises in deaths partly to the aging of the world's population, rapid urbanization and increased exposure to risk factors, particularly in low-and middle-income countries."This is a landmark meeting," said UN Secretary-General Ban Ki- moon at the opening of the unprecedented meeting. "Three out of every five people on earth die from the diseases that we gather here to address."The last time the UN looked at a health issue under the global microscope on such a high-level was almost a decade ago.

KATHMANDU, Aug. 3 (Xinhua) -- Two glaciers in Nepal that shrank at an accelerated rate in the past 10 years compared to preceding decades will inevitably disappear from rising temperatures as no fresh snow supply is expected for them, a new research by Japan's Nagoya University says.According to Wednesday's Republica daily, the masses of the Yala glacier of Langtang Himal in central Nepal and the AX010 glacier of Shorong Himal in the Khumbu region shrank annually by 0. 8 meters and 0.81 meters respectively in the 2000s, which was a significant acceleration from the 0.68 and 0.72 meters of shrinkage per year between 1970 and 1990, said findings of the research published in a journal of the National Academy of Sciences of the United States on Tuesday."If the trend since the 1990s continues for the Yala and AX010 glaciers, the disappearance of these glaciers is inevitable because they are about to lose their accumulation areas, thus, no snow supply is expected for these glaciers," says the research conducted by Koji Fujita and Takayuki Nuimura.The researchers also found that while the shrinking of glaciers has accelerated in humid environments, the opposite is true for those in arid environments. The shrinking of Rikha Samba glacier located in the Kaligandaki Hidden Valley slowed from 0.57 meters per year between 1970 and 1990 to 0.48 meters per year in the 2000s."A comparison of the mass balance results and annual precipitation reveals that glacier wastage has been accelerated in humid environments but suppressed in an arid environment," the research says.Apart from environment, altitude also appears to play a role in the lifespan of glaciers, the researchers say. Rikha Samba is located at an altitude of 5,700 meters where loss of mass from melting could be compensated to some extent by collection of snowfall.The Yala glacier and AX010, on the other hand, are located at lower altitudes of 5,400 meters and 5,200 meters respectively.

SAN FRANCISCO, June 20 (Xinhua) -- Facebook will launch new music service with a music tab and music dashboard in partnership with other online music services at its f8 annual developer conference in August, U.S. media reported on Monday.According to technology blog GigaOM, users will find a new tab called Music in the left-hand column on their pages, right where Facebook lists Photos, Friends, Deals and etc., and clicking on the new tab will open a page called Music Dashboard.The dashboard will feature friends' recommended songs, top songs, top albums and a "happening now" ticker that shows songs friends are playing.The blog said Facebook had reached partnership with Europe's popular music streaming service Spotify, which is gearing up to enter the U.S. market, and other online music services.Much of the attention at f8 should be focused on music, the blog quoted sources as saying.Last month, Facebook CEO and co-founder Mark Zuckerberg said at the eG8 Forum in Paris that he believes Facebook will focus on streaming music next.

SYDNEY, June 29 (Xinhua) -- A type of dried seaweed sold in Asian food supermarkets in Australia has been recalled after it was found to have high levels of iodine dangerous to pregnant women, local media reported on Wednesday.Food Standards Australia New Zealand (FSANZ) has ordered the recall of Wang Dried Kelp Varech Speche, a Korean brand of the dried seaweed, according to Australian Associated Press (AAP).It has been available in Asian grocery stores and restaurants in the Brisbane and Gold Coast areas of Queensland."The product contains high levels of naturally occurring iodine," FSANZ said in a statement."Regular consumption of these products may cause health problems in some people including pregnant and breastfeeding women."FSANZ said consumers concerned about their health should seek medical advice and should return the products to the place of purchase for a full cash refund.

来源：资阳报