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WASHINGTON, June 8 (Xinhua) -- Hundreds of small genetic variations are associated with autism spectrum disorders, including an area of DNA that may be a key to understanding why humans are social animals, according to a multi-site collaborative study led by researchers at Yale University.To be published Thursday in the journal Neuron, the study reinforces the theory that autism, a disorder that develops in early childhood involving impairments in social interaction, language deficits and distinctive behaviors, is not caused by one or two major genetic defects, but by many small variations, each associated with a small percentage of cases.The study looked at more than 1,000 families in which there was a single child with an autism spectrum disorder, an unaffected sibling and unaffected parents. The team compared individuals with autism to their siblings to determine what types of genetic changes distinguished the affected child from the unaffected child.One of the most intriguing of these findings points to the same small section of the genome that causes Williams syndrome -- a developmental disorder marked by high sociability and an unusual aptitude for music.In autism, there is an increase in the chromosomal material, an extra copy of this region, and in Williams syndrome, there's a loss of that same material," said lead author Matthew State. "What makes this observation particularly interesting is that Williams syndrome is known for a personality type that is highly empathetic, social, and sensitive to the emotional state of others. Individuals with autism often have difficulties in the opposite direction. This suggests that there is an important key in that region to understanding the nature of the social brain."State and his team also found about 30 other regions in the genome that are very likely contributing to autism and are focused on about six of those regions that showed the strongest evidence."We're now moving on to a second phase of the study looking at an additional 1,600 families and should be able to identify multiple new regions that are strongly implicated in autism," he said.

SAN FRANCISCO, Aug. 9 (Xinhua) -- Nokia is planning to stop selling its low-end phones and smartphones in the United States, instead focusing on products using Microsoft's Windows Phone platform, U.S. media reported on Tuesday.The Finnish handset maker will end sales of its low-end Series 40 phones and smartphones based on the Symbian mobile operating system in the United States and Canada, as it needs to put all of its efforts into the Windows Phone products which are due out later this year, Chris Weber, head of Nokia's U.S. subsidiary, told technology news site All Things Digital."When we launch Windows Phones we will essentially be out of the Symbian business, the S40 business, etc.," Weber said.Staff members speak to trade visitors at the Nokia booth at the CommunicAsia expo in Singapore June 21, 2011.In February, Nokia and Microsoft announced plans to form a broad strategic partnership, under which Nokia agrees to adopt Windows Phone as its principal smartphone strategy.North America is a priority for Nokia, Weber noted, in part because it is a key market for Microsoft and also because Nokia sees it as a key to winning in the smartphone battle globally."We'll develop for North America and make the phones globally available and applicable," Weber said.In another development, technology blog Engadget and other U.S. media on Tuesday reported that Nokia will not bring N9, its first smartphone running the Linux-based mobile operating system MeeGo, to the U.S. market."After the very positive reception to the launch of the Nokia N9, the product is now being rolled out in countries around the world. At this time we will not be making it available in the U.S., " Nokia said in a statement.

WASHINGTON, June 6 (Xinhua) -- A new University of Missouri study shows that the exposure to the controversial chemical Bisphenol A (BPA) through diet has been underestimated by previous lab tests.The findings were published on Monday in Environmental Health Perspectives.In the study, researchers compared BPA concentrations in mice that were given a steady diet supplemented with BPA throughout the day, compared to the more common lab method of single exposure, and found an increased absorption and accumulation of BPA in the blood of the mice.The authors continuously exposed the mice to BPA through their feed, which is considered the primary route of exposure to this chemical in animals and humans. In previous studies examining the effects of BPA, mice were exposed to BPA only through a one-time administration.Following the exposure through the diet, a significantly greater increase in the active form of BPA, which is the greatest threat as it is the form that can bind to sex steroid receptors and exert adverse effects, was absorbed and accumulated in the animals."People are primarily and unknowingly exposed to BPA through the diet because of the various plastic and paper containers used to store our food are formulated with BPA," said Cheryl Rosenfeld, associate professor in biomedical sciences and corresponding lead author. "We know that the active form of BPA binds to our steroid receptors, meaning it can affect estrogen, thyroid and testosterone function. It might also cause genetic mutations. Thus, this chemical can hinder our ability to reproduce and possibly cause behavioral abnormalities that we are just beginning to understand."The study notes that more than eight billion pounds of BPA are produced every year, and more than 90 percent of people in the United States have measurable amounts of BPA in their bodies."When BPA is taken through the food, the active form may remain in the body for a longer period of time than when it is provided through a single treatment, which does not reflect the continuous exposure that occurs in animal and human populations," said Rosenfeld. "We need to study this further to determine where the ingested BPA becomes concentrated and subsequently released back into the bloodstream to be distributed throughout the body."

BEIJING, June 12 (Xinhua) -- A senior Chinese official has called the country's police to better serve the people when the Communist Party of China (CPC) is meeting the 90th founding anniversary.Zhou Yongkang, member of the Standing Committee of the Political Bureau of the CPC Central Committee, made the remark on Sunday evening in meeting with top 10 favorite police officers selected through a nationwide vote.The Ministry of Public Security (MOPS) and the China Central Television have jointly conducted My Favorite Police Officer Competition in the past eight years.This year's winners include 75-year-old detective Wu Guoqing, network security police officer Li Qing from Jiangsu Province, traffic police officer Wu Hao of Miao Nationality from Hunan Province, female SWAT team leader Pan Qin from Guizhou Province.Zhou said that this year's competition attracted more than 150 million online voters which means more and more people are supporting the activity, and all winners should cherish the honor and better serve the people on their own posts.The official called on police officers around the country to learn from the 10 favarite officers and other winners in the competition who have all made outstanding contribution to the security of the people and society.

NAIROBI, Aug. 18 (Xinhua) -- The World Health Organization (WHO) on Thursday decried increased number of confirmed cholera cases in the Somalian capital Mogadishu, and growing reports of acute watery diarrhea in Kismayo and other crowded urban centers, saying an urgent multi-sector response to contain the spread of this highly contagious disease is being mounted.The UN health agency said has confirmed cholera in Banadir, Bay, Mudug and Lower Shabelle regions and the number of acute watery diarrhea cases has increased dramatically in the last few months.WHO Representative for Somalia Marthe Everard said combination of poor sanitation conditions, a shortage of safe water, overcrowding and high malnutrition rates, creates the perfect combination for infectious diseases, such as cholera and pneumonia, to spread and increase the number of deaths. "For the last few years, a network of health workers reporting to the early warning system is in place, however they report through a health facility or mobile clinic. Yet the large numbers of displaced people in Mogadishu are making it more difficult to record the various diseases," Everard said in a statement issued in Nairobi. "We urgently need more mobile clinics that will provide basic health care services to the many displaced and who will strengthen the reporting on new outbreaks. This is critical to our response and our ability to save lives."According to WHO, about seventy-five percent of all cases of acute watery diarrhea are children under the age of five.Since January this year, 4,272 cases of acute watery diarrhea/ cholera have been reported in Banadir Hospital in Mogadishu alone. However, at this stage most of the cholera cases in the various regions are contained and under control. "Our major concern is to monitor and detect new disease outbreaks in the many informal settlements set up by internally displaced people in and around Mogadishu", says Everard.Although cholera is endemic in the country, the last major cholera outbreak was in 2007 with an estimated 67,000 cases.WHO said recent efforts to cholrinate the water supply of Mogadishu, along with efforts to improve hygiene and sanitation have prevented a serious outbreak but with the large influx of some 100,000 people alone this year into Mogadishu, bringing the total number of IDPs in the capital to an estimated 470,000, many are living in overcrowded settlements, there is an acute shortage of safe water and adequate sanitation. "There is no need for a child to die of diarrhea, yet this is tragic reality for a Somali child, who is acutely malnourished. It is a lethal combination." said Rozanne Chorlton, UNICEF Representative for Somalia. "These types of diseases can be prevented and treated quickly, but to save children's lives we need to make sure safe water, sanitation and hygiene along with early access to primary health care, are an integral part of our emergency response."WHO said partners in the health and water and sanitation sectors are currently preparing for a potential 100,000 cholera cases including 80,000 moderate cases and 20,000 severe cases.Emergency diarrheal disease kits made up of medical supplies such as syringes, infusions, and oral rehydration fluids (ORS), already prepositioned by UNICEF and WHO have been sent to 13 hospitals.An additional 200 diarrheal disease kits, each able to treat 100 severe cases and 400 moderate cases are being procured and should be in Southern Somalia in the next few weeks, it said.In addition, WHO said, the case management of severe dehydration with and without malnutrition is being strengthened and focus is now on mobilizing a network of already trained community health promoters to move from door to door with health hygiene education messages. "Health posts will be stocked with essential medicines and ORS to identify and promptly treat patients. Many of Southern Somalia' s rural areas and urban centers rely on shallow wells, which unless protected or treated with chlorine can serve as the perfect breeding ground for water borne diseases," it said.To respond to this threat and prevent a major outbreak, the UN health agency said partners in the water, sanitation and hygiene sector are scaling up their actions to target 1.5 million people across high risk areas of the south.Supplies of chlorine and essential items for hygiene and household treatment and storage of water are being distributed.Already 217 water sources are being chlorinated and 58 water point outlets benefitting 483,200 residents and internally displaced people in Mogadishu.In addition, household hygiene supplies, including water purification tablets, soap and buckets, enough for 48,000 families, are being distributed at existing feeding centers for malnourished children.Campaigns to educate families about the treatment of drinking water, safe disposal of waste and encourage hand washing with soap will also be scaled up in high risk communities.As part of the updated 2011 UN Consolidated Appeal for Somalia, an estimated 80 million U.S. dollars is needed for the health sector and 78 million dollars is required for the water, sanitation and hygiene sector.So far, each sector has respectively raised 30 percent and 37 percent of the required money.

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