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CAMP PENDLETON, Calif. (KGTV) — One man was killed early Thursday after his vehicle overturned and he was thrown from the vehicle in the North County.The crash occurred just before 5 a.m. on southbound Interstate 5, south of Basilone Rd., according to California Highway Patrol. CHP believes the 40-year-old driver of a Toyota 4-Runner was traveling southbound when for unknown reasons, he left the roadway. The vehicle overturned and the man was thrown from the SUV.CHP, Camp Pendleton Fire Department, and North County Transit District responded to the scene, but the man died at the scene. He was not immediately identified.Investigators said they don't believe alcohol or drugs were a factor in the crash, and are still looking into the crash. 755

Bulked-up, mutant “mighty mice” held onto their muscle during a monthlong stay at the International Space Station, returning to Earth with ripped bodybuilder physiques, scientists reported Monday.The findings hold promise for preventing muscle and bone loss in astronauts on prolonged space trips like Mars missions, as well as people on Earth who are confined to bed or need wheelchairs.A research team led by Dr. Se-Jin Lee of the Jackson Laboratory in Connecticut sent 40 young female black mice to the space station in December, launching aboard a SpaceX rocket.In a paper published in the Proceedings of the National Academy of Sciences, Lee said the 24 regular untreated mice lost considerable muscle and bone mass in weightlessness as expected — up to 18%.But the eight genetically engineered “mighty mice” launched with double the muscle maintained their bulk. Their muscles appeared to be comparable to similar “mighty mice” that stayed behind at NASA’s Kennedy Space Center.In addition, eight normal mice that received “mighty mouse” treatment in space returned to Earth with dramatically bigger muscles. The treatment involves blocking a pair of proteins that typically limit muscle mass.A SpaceX capsule brought all 40 mice back in good condition, parachuting into the Pacific off the California coast in January. Some of the ordinary mice were injected with the “mighty mice” drug after returning and quickly built up more muscle than their untreated companions, Lee said.The scientists completed the experiment just as the coronavirus was hitting the U.S.“The only silver lining of COVID is that we had time to write it up very intensively” and submit the results for publication, said Dr. Emily Germain-Lee of Connecticut Children’s Medical Center, Lee’s wife who also took part in the study. Both are affiliated with the University of Connecticut.While encouraged by their findings, the couple said much more work needs to be done before testing the drug on people to build up muscle and bone, without serious side effects.“We’re years away. But that’s how everything is when you go from mouse to human studies,” Germain-Lee said.Lee said the experiment pointed out other molecules and signaling pathways worth investigating — “an embarrassment of riches ... so many things we’d like to pursue.” His next step: possibly sending more “mighty mice” to the space station for an even longer stay.Three NASA astronauts looked after the space mice, performing body scans and injections: Christina Koch and Jessica Meir, who performed the first all-female spacewalk last fall, and Andrew Morgan. They are listed as co-authors.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 2835

CHANDLER, AZ — The Arizona Attorney General’s Office says Mikal Lee Smith, the son of ex-NFL coach and current head of the University of Illinois football program Lovie Smith, has been indicted after a Chandler police investigation accusing him of running a prostitution ring.According to a release, between December 2018 and September 2019, Mikal Smith and Aprel Mae Rasmussen operated and maintained an illegal prostitution enterprise.In one instance, Mikal Smith and Rasmussen allegedly induced and encouraged an adult female victim to “engage in acts of prostitution for over two months.”Mikal Smith reportedly used surveillance and threats of retaliation to keep the victim under his control.It’s unclear how many other victims, if any, were involved. The Chandler police did not immediately respond to a request for comment.Mikal Smith has been indicted on charges of conspiracy, illegally conducting an enterprise, money laundering in the first degree, pandering, receiving earnings of a prostitute, sex trafficking, and threatening or intimidating.His co-defendant, Aprel Rasmussen, was indicted on charges of conspiracy, illegally conducting an enterprise, money laundering in the first degree, and pandering.Mikal Smith played football for the University of Arizona and was an assistant coach in the NFL for the Chicago Bears, Dallas Cowboys, and Tampa Bay Buccaneers for several years.This story was originally published by Clayton Klapper on KNXV in Phoenix. 1478

CALEXICO, Calif. (KGTV) - Nearly two and a half miles of the current border wall along the U.S.-Mexico border in Calexico are being replaced with 30-foot high, bollard-style walls.The section of the replacement, which broke ground last week, extends from the Calexico Port of Entry westward just past Gran Plaza Outlets, according to Customs and Border Protection officials. The project also includes 2.25 miles of all-weather roads.CBP officials tweeted out photos of the construction Thursday, saying "replacement project in Calexico is going well. 30-foot tall steel bollard wall is stacked on the ground waiting to be installed after the removal of old landing mat barrier."RELATED: President Trump to visit San Diego, inspect border wall prototypesThe section under construction was built in the 1990s out of recycled metal scraps and old landing mat.While officials said the wall has proven effective, "smuggling organizations damaged and breached this outdated version of a border wall several hundred times during the last two years," resulting in costly repairs.The construction is separate from President Donald Trump's promised wall across the border. The project is the first border construction contract awarded by the Trump administration, aside from the eight prototypes for a new wall built near Otay Mesa last year.INTERACTIVE TIMELINE: President Trump's border wallThe president is expected to make a visit to view the prototypes sometime in March.While a federal judge sided with the Trump administration in a lawsuit against the wall by environmental groups and California, Trump tweeted California's portion of the wall is on hold until the entire wall is approved. 1749

BUFFALO, N.Y. - With the prospect of a tailgating-less season looming for the Buffalo Bills, one fan is hoping to bring fans together to give back."Bills fans always pull through," Sue Cycon said.Cycon is hoping that the money Bills fans save by not tailgating can be donated, hoping to benefit Western New York. "Donate Your Beer Money" will be held from Sept. 20-Oct. 11 at a local Buffalo restaurant called Danny's.The socially distant donation event will be taking food donations for FeedMoreWNY, school supplies for children around Western New York, and monetary donations for Roswell Park Comprehensive Cancer Center, particularly their pediatric care unit. Donate your beer money campaign "Anywhere from immunotherapy to clinical trials, that's where those funds go," Alexandria Hoaglund of Roswell Park said.Donations can already be made to Roswell through the "Donate Your Beer Money" campaign at the link here.Donations will be accepted through drive-through donations. Simply drive into the parking lot at Danny's, roll your window down and someone will grab the donations.This story was first reported by Jeff Slawson at WKBW in Buffalo, New York. 1197

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