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BERLIN, Jan. 17 (Xinhua) -- Researchers in Germany have found a cheap and easy way to synthesize anti-malaria drug in large quantities from waste materials, said the Max Planck Society on Tuesday.Currently there are nearly one million people die worldwide each year due to lack of effective drugs, as sweet wormwood, from which artemisinin, the effective essence to fight malaria can be extracted, only grows in China, Vietnam and a few other countries.However, researchers in Germany have now developed a simple process for the synthesis of artemisinin in laboratory, using artemisinic acid, a substance contained in the by-product, or waste materials of the isolation of artemisinin from sweet wormwoods, as row materials of synthesizing artemisinin."The production of the drug is therefore no longer dependent on obtaining the active ingredient from plants," said Peter Seeberger, director at the Max Planck Institute of Colloids and Interfaces in Potsdam and professor at Free University of Berlin.The artemisinic acid in the waste material boasts a volume 10 times greater than the active ingredient itself, said Seeberger, and they could be turned into artemisinin in four and a half minutes in a so-called continuous-flow reactor.Seeberger estimated that 800 of the reactors would be enough to cover the global requirement for artemisinin, and the whole innovative synthesis process could be ready for technical use in three to six months.Malaria is a disease caused by parasites that are transmitted to people through the bites of infected mosquitoes. In 2010, malaria caused an estimated 655,000 deaths, mostly among African children.
BEIJING, Oct. 11 (Xinhuanet) -- An experimental drug that can remove amyloid plaques from the brains of Alzheimer's patients is being developed by Swiss Roche Holding AG in a small early-stage study, according to a report published in the Archives of Neurology on Monday.Researchers suspect the build-up of such plaques may be a cause of the memory robbing disease, although that theory has yet to be definitively proved. Gantenerumab, a biotech drug designed to bind to amyloid plaques in the brain and remove them, is being targeted at the early stages of Alzheimer's with the hope it can slow progression of the disease while patients are still able to function.The Phase I study of 16 Alzheimer's patients tested gantenerumab at two doses against a placebo over six months of treatment.The Roche drug led to a dose-dependent reduction of brain amyloid, while amyloid load increased in patients receiving a placebo, the report said.The next step will be to investigate whether removal of brain amyloid translates into clinical benefit for patients at doses of the experimental drug that are well tolerated and safe, the report said.Much larger trials and further study will be needed to fully understand how gantenerumab works and whether it can stave off Alzheimer's, said the report.Roche is approaching the disease far earlier because amyloid accumulates for 15 years before dementi.
BEIJING, Dec. 12 (Xinhuanet) -- For many multinational firms, the past 10 years in China have not only marked the rise of the world's second-largest economy but have also been a decade of expansion and profit growth.As they look back at this "golden decade", which is often used to describe the days after China entered the World Trade Organization (WTO) in 2001, their early expectations and ambitions in a more liberalized Chinese market were found to be more than fulfilled.When German auto giant BMW set foot on the Chinese mainland by establishing its first office in Beijing in 1994, its products were still far too luxurious for ordinary Chinese.In 2001, only 6,500 vehicles were sold under the BMW and Mini brands in China.NYK Diana, a container ship, anchors at Qingdao Port in East China's Shandong province on Thursday, as workers load cargo.But sales started to pick up with China's WTO entry, when the removal of trade barriers brought unprecedented economic growth and a booming market.In 2010, the vehicle maker, which started a joint venture with the domestic Brilliance China Automotive in 2003, sold 169,000 vehicles in China.That record is set to be broken this year as more than 170,000 cars were sold only in the first three quarters."We are both beneficiaries and firm supporters of the open market system," said Christoph Stark, president and CEO of BMW's Greater China region.By liberalizing its market, China, which celebrated the 10th anniversary of its WTO accession on Sunday, has become a thriving market and a savior for foreign enterprises hit hard by the global downturn.In 2009, when General Motors declared bankruptcy in the United States amid the global recession, its Chinese branch saw sales rise 66.9 percent year-on-year to more than 1.8 million units.In 2010, China overtook the United States to become GM's largest national market.The list of similar companies is extensive, as China's decade-long membership of the WTO has helped the Asian powerhouse attract 347,000 foreign firms with investment of more than 0 billion in the past 10 years.Chong Quan, deputy representative for China's international trade talks, said foreign enterprises made more than 0 billion in profit in the 10-year period, with an average annual increase of 30 percent."The accession to the WTO has made China a more transparent, safe and predictable market, as well as an essential part of the global economy," said Dominique Poulique, president of Alstom China.The French power engineering and train company, with more than 30 entities and about 10,000 employees in China, is one of the major foreign suppliers to the Chinese rail transport market."Rapid changes took place in China in the past decade, with its massive investment in infrastructure construction and notable development in energy," Poulique said.Wang Zhile, director of the research center of transnational cooperation under the Ministry of Commerce, said increasing shared interests between China and multinationals are putting them into an inseparable community, one that has found win-win solutions in the past decade.There is also high-quality labor at a relatively low cost, including white-collar workers, he added.Admittedly, the huge market and rich resources have powered up multinational firms in global competition, especially during and after the financial crisis.Forty-nine percent of the responding multinational companies had higher expectations for China in the wake of the global financial crisis in 2008 and 2009, according to a recent survey by the Economist Intelligence Unit, a business information arm of the Economist Group.Although showing signs of a slowdown, China's economy is still widely expected to grow by more than 8 percent next year, at a time when debt and financial instability are weakening growth in other leading economies.Poulique said he expected China's rapid growth to continue into the next decade, especially in the infrastructure construction market."For Alstom, the top task here is to keep adapting to the changing business environment," he said.Many foreign companies are moving research and development facilities to China in the hopes of making it a base for talent and technology.In Shanghai, 347 multinationals have set up regional headquarters, with the establishment of 333 foreign-funded research and development centers.