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SAN DIEGO (CNS) - The Collaborative Clinical Trials Unit at UC San Diego has been selected to lead and administer an international seven-year, million grant for HIV/AIDS clinical trials.The National Institutes of Health selected UCSD, along with other American, South African and Indian research hospitals, as part of its seven-year HIV/AIDS funding renewal. Every seven years, NIH competitively renews its funding of the HIV clinical trials networks operating in the United States and internationally.During the current application process, the UC San Diego AntiViral Research Center, University of Colorado Hospital, Houston AIDS Research Team and Durban International clinical research sites were chosen to work collaboratively on research priorities for the NIH/National Institute of Allergy and Infectious Diseases HIV/AIDS Adult Therapeutics Clinical Trials Network.The Chennai Antiviral Research and Treatment Center, University of Southern California and University of Miami clinical research sites were also chosen to join UCSD to serve as qualified reserve or protocol-specific sites as needed for future clinical trials."UC San Diego has helped shape HIV/AIDS research and treatment through innovative research since the inception of the adult and pediatric therapeutic clinical trials networks in 1986," said principal investigator Dr. Constance A. Benson, director of UCSD's Antiviral Research Center."Together, the seven clinical research sites selected by the NIH for the HIV therapeutic clinical trials network bring together a wealth of scientific expertise, experience and the high quality performance required to conduct complex clinical trials," she said.Abouty 38 million people are living with HIV/AIDS globally, with 1.7 million acquiring HIV in 2019 alone. In the United States, 1.2 million people are living with the virus.The UCSD-led clinical trials unit serves several regions in the United States burdened by chronic and new HIV infections as well as global regions impacted by both HIV and tuberculosis.The unit will investigate therapeutic strategies aimed at a cure for HIV, including evaluating viral persistence, researching antibody approaches to treatment and prevention and investigating treatment of inflammation and its impact on HIV comorbidities.In addition, investigators will study new drugs including long-acting drug formulations for HIV treatment and prevention, HIV-related coinfections and comorbidities -- including metabolic and end organ complications and a hepatitis B cure, as well as the treatment and prevention of tuberculosis, including TB preventive vaccines, in persons with mono- and HIV-coinfection."We are honored to lead a talented pool of investigators in a common goal of advancing research that clinically benefits people living with HIV," Benson said. 2830

SAN DIEGO (CNS) - On the day after Thanksgiving, County of San Diego Department of Parks and Recreation encourages San Diegans to swap shopping plans for outdoor experiences Friday on "Green Friday," a park-centric holiday celebrating the "upside of outside."Green Friday promotes fitness and fun in county parks. Events are intended to be active and educational -- aligning with county parks' mission to balance recreation opportunity with efforts to protect and preserve land and local wildlife.Activities are open to the public and there is no cost to attend. The day-use fees at parks where they are collected will be waived.From Story Trails and tree planting to virtual nature trivia and fitness meet-ups, all in-person outdoor activities will follow public health orders and require face coverings and social distancing. San Diego County Credit Union is one of the sponsors of the event."We are pleased to support the County of San Diego and Live Well San Diego and help spread the word about this exciting initiative," said Teresa Campbell, SDCCU president and CEO. "San Diego County offers some of the most beautiful parks, preserves and beaches in the region and we encourage members of the community to get outside and enjoy Green Friday safely."Two volunteering events are part of the day. Plant trees at Flinn Springs and Live Oak County Parks. All ages welcome and trees and materials will be provided.Protective clothing, sturdy shows and gloves are recommended, as is bringing food and water.-- Flinn Springs County Park in El Cajon from 10 a.m. to 1 p. m. Register by calling 619-561-0180-- Live Oak County Park in Fallbrook from 11 a.m. to 2 p.m. Register by calling 760-728-2303.Several county-run workouts are available, with free fitness classes. Attend a fit camp session led by Mission Fit Camp's trainers at Pioneer Park. Wear comfortable clothing and bring water and a towel.-- All-ages Fit Camp at San Diego's Pioneer Park: 9 - 10 a.m., Max. 25 people.-- Adults Fit Camp at San Diego's Pioneer Park: 12 - 1 p.m., Max 25 people.-- Yoga session at Waterfront Park Civic Green 4, led by Dorothy Guthrie: 1 - 2 p.m., Max. 20 people; RSVP through Hannah Reynolds at Hannah.Reynolds@sdcounty.ca.gov.The County Board of Supervisors launched Live Well San Diego in 2010 with the goal of achieving healthy, safe and thriving communities across the region by partnering with community and city leaders, schools, businesses, non- profit organizations and residents.For more information and a full list of activities visit https://www.sdparks.org/content/sdparks/en/participate/GreenFriday.html. 2617

SAN DIEGO (CNS) - The San Diego County Board of Supervisors voted unanimously Tuesday to extend an agreement with Southern California Edison to receive emergency planning funds from the utility as it removes spent nuclear fuel from the decommissioned San Onofre Nuclear Generation Station.The county's Office of Emergency Services entered a similar memorandum of understanding with SCE in 2015, through which the company provided radiological emergency planning funds to five jurisdictions around the plant, including San Diego County, through the end of Fiscal Year 2019-20.A county staff report estimates SCE will pay the county 6,500 in the remainder of the agreement.The remainder of the spent fuel is planned to be moved from spent fuel pools to dry cask storage by the end of this summer, but the memorandum approved by the board runs through the end of Fiscal Year 2049 or whenever all spent fuel is removed from the site -- whichever comes first.The federal Nuclear Regulatory Commission and the State of California do not require decommissioned nuclear power plants to reimburse local jurisdictions for emergency planning, but SCE has agreed to continue paying jurisdictions surrounding the plant, for planning and preparation for radiological emergencies.San Onofre hasn't produced power since a steam leak in 2012, and SCE closed the plant the following year and began decommissioning activities.When the California Coastal Commission voted 9-0 last October to allow SCE to begin dismantling the plant, the canisters were being moved from a "wet storage" facility to a newly constructed "dry storage" facility on the site. San Onofre is located on 85 acres of the Camp Pendleton Marine Corps base and is home to 3.55 million pounds of spent nuclear fuel, the San Diego Union Tribune reported last year.The nuclear waste is being stored in self-cooling canisters which take in cool air and expel hot air. 1925

SAN DIEGO (CNS) - Several San Diego County parks will close for the month of August, in a precautionary move taken annually due to expected extreme heat levels, the county Parks and Recreation department announced today.El Capitan Preserve near Lakeside, Mt. Gower Preserve near Ramona, Hellhole Canyon Preserve in Valley Center and Wilderness Gardens in Pala will close Wednesday.Additionally, Agua Caliente Regional Park and Vallecito County Park in the Anza-Boreggo Desert are closed all summer.Related Links:  526

SAN DIEGO (CNS) - Playgrounds in San Diego County can reopen to the public Wednesday, despite initially being closed under COVID-19 restrictions, after state health officials reversed course.Assemblywoman Lorena Gonzalez, D-San Diego, led a group of a dozen legislators who sent a letter to Gov. Gavin Newsom last week urging him to remove playgrounds from the stay-at-home order. They claimed opening playgrounds "is necessary for the mental and physical health of children to have opportunities to expend their physical energy and play." They also noted that in some low-income neighborhoods, "families may have little to no outdoor space of their own available."Newsom and the California Department of Public Health revised statewide public health guidelines on Wednesday to allow for public playgrounds to remain open."Every parent knows how important playgrounds are for our youngest Californians," Gonzalez said. "A huge thank you to Governor Newsom for hearing our collective concern and rethinking how we can open play structures for our kids."Playgrounds were closed earlier in the pandemic before being reopened in September. Then, with a spike in case rates and the state's issuance of a regional stay-at-home order, which took effect late Sunday night across all of Southern California, playgrounds closed again.Pressure from parents and legislators have now caused the state to reopen the playgrounds.According to the state's website, "playgrounds may remain open to facilitate physically distanced personal health and wellness through outdoor exercise. Playgrounds located on schools that remain open for in-person instruction, and not accessible by the general public, may remain open and must follow guidance for schools and school-based programs."San Diego County Supervisor Jim Desmond made a motion at the Board of Supervisors meeting Tuesday to defy the state order and not enforce the playground closure. It was rejected 3-2.Supervisor Nathan Fletcher said his conversation with state officials proved productive, and gave credit to Gonzales -- his wife -- for her work."Kids in San Diego County can now enjoy local playgrounds. This is something that can be done safely and make the lives of families easier," Fletcher said. "My conversations with California Governor Gavin Newsom and Secretary Dr. Mark Ghaly worked, and I appreciate their partnership on this adjustment.""Thank you to everyone who worked cooperatively with the state, to bring about this adjustment, our collective efforts made a difference, special shout out to my wife, supermom, Assemblywoman Lorena Gonzalez," he said. 2621