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WAUWATOSA, Wis. — A 3-year-old in Wisconsin can see for the first time thanks to a new procedure. McKinley Sovey is the youngest person to undergo this type of gene therapy. Her parents Parker and Julie Sovey have been watching her progress."There was that moment when she did look at me for the first time," said Julie. "I was like I think this is working. I can't even really explain it. She's 3 years old and she looks at mom for the first time. It was a really really cool moment and it was the moment I was waiting for."McKinley was born practically blind. The most she could see was the contrast of light. When she was a year and a half, doctors discovered she inherited a retinal disease. "Six months after that FDA approval, and then less than a year after that she's having the procedure, so it's been like rapid fire," Parker said. Dr. Stephen Russell works in the Department of Ophthalmology and Visual Sciences at the University of Iowa Hospital. He performed both of McKinley's eye surgeries with the gene therapy earlier this month. "Complicated drug because it has multiple parts to the drug and complicated surgery because to make sure we delivered the drug to the appropriate tissues," said Russell.Russell said he is basically forcing DNA into the right cell."We had to do a surgery just to put the solution in the appropriate spot, which is in the area underneath the retina," he said. "At that point, it's just fingers crossed that this gene ends up in the spot that it's supposed to," said Julie.The Soveys knew there were risks and potential complications. "It's terrifying," said Russell.They were hoping the therapy would at least help McKinley maintain the little vision she had. After the first eye surgery, mom and dad didn't notice a difference. But it was shortly after the second surgery they knew it worked. Parker said she was moving with a purpose."She walked into the kitchen, pulled a chair out, stood up on the chair and actively feeling like the toaster and the coffee maker like she knew those were there and she wanted to get up and be able to feel them," he said.McKinley's depth perception is also changing."Being able to see things further away has been really neat and it's also been kind of scary because I feel like I'm having to re-childproof the house for a 3-year-old," said Julie."She use to feel around for whatever it was she was eating," Parker said. "Then she'd put her hands in it to see what it was and then she'd put the spoon in it, and then usually it was dumped by the time it got to her face."McKinley will still likely be visually impaired, but her parents said any progress is a bonus."She may no longer need to be a braille reader," Julie said. "I don't know if she'll need to use a cane to navigate."They said their daughter is becoming more confident and her personality is even changing."This is kind of part of medical history," said Julie.McKinley has some checkups scheduled, but doctors hope she won't need another surgery. 3071
WASHINGTON (AP) — The U.S. Supreme Court has preserved an important tool used by securities regulators to recoup ill-gotten gains in fraud cases.The justices said by an 8-1 vote Monday that the Securities and Exchange Commission can seek to recover the money through a process called disgorgement.Last year, the SEC obtained .2 billion in repayment of profits from people who have been found to violate securities law.Justice Sonia Sotomayor wrote for the court that the award must be limited to no more than “a wrongdoer’s net profits."Justice Clarence Thomas dissented. 581

WASHINGTON, D.C. – It’s a convergence of two health crises: the ongoing coronavirus pandemic and a new flu season now underway.“There’s not much flu in the northern hemisphere in the summer - but there is a lot in the southern hemisphere,” said Dr. Amesh Adalja, a senior scholar at the Johns Hopkins Center for Health Security and an infectious disease critical care and emergency medicine physician.Dr. Adalja said health care professionals have observed the flu in places like Australia and New Zealand during the past several months, which could offer clues into what might be expected here as our weather gets colder.“The southern hemisphere has had a remarkable flu season mostly because it's 99% lower than what they've seen in prior years,” Dr. Adalja said. “This has to do with the fact that the social distancing that people are doing for COVID-19 also has an impact on influenza because they're both spread in the same manner.”However, the U.S. has failed to control the spread of the coronavirus, leading to fears that the country might be facing a “twindemic,” where COVID-19 and the flu collide.The one silver lining: less international travel around the world may make it harder for the flu to spread globally like it has in years past.“The point we have to continue to emphasize is we don't know for sure if we'll have a light flu season and we have to prepare for one that's severe,” Dr. Adalja said.So far, the coronavirus has killed more than 210,000 people in the U.S. this year. According to the Centers for Disease Control, that’s more than the previous five flu seasons combined.Estimated flu season deaths:2015-16: 23,0002016-17: 38,0002017-18: 61,0002018-19: 34,0002019-20: 22,000Total 2015-2020: 178,000Still, any uptick in hospitalizations because of the flu could further strain hospitals already dealing with COVID-19. One region of concern is the upper Midwest, in places like Wisconsin, which is a current coronavirus hotspot."It is stretching our hospital capacity, and it is overwhelming our public health infrastructure,” said Andrea Palm of the Wisconsin Department of Health Services.One step that could help is to ensure everyone gets a flu shot, even if it doesn’t end up being a perfect match to this year’s strain.“Even if it isn't a complete match and it doesn't prevent you from getting the flu, it still will prevent you from dying from influenza and getting hospitalized with influenza or getting complications from influenza,” Dr. Adalja said.It is also now one of the few tools available in a time of great uncertainty. 2573
WASHINGTON (AP) — The U.S. has given the final go-ahead to the nation's first COVID-19 vaccine, launching emergency vaccinations in a bid to end the pandemic. Shots will begin in a few days after Friday's decision by the Food and Drug Administration. The FDA called the vaccine from Pfizer and its German partner BioNTech safe and strongly protective. After the FDA approved the vaccine, President Donald Trump thanked the FDA and praised both Pfizer and Moderna in a video posted to his Twitter account. 512
WASHINGTON, D.C. – The Internal Revenue Service (IRS) says it’s sticking with its July 15 deadline for Americans to file and pay their federal taxes.The original filing deadline and payment due date for 2019 was postponed from April 15 to July 15 due to the coronavirus pandemic.However, the IRS says taxpayers who are unable to meet the July 15 deadline can request an automatic extension of time to file until Oct. 15. You can file for an extension here.Those filing for an extension must do so by July 15. The IRS says the extension provides additional time to file a tax return, but it’s not an extension to pay any taxes due.The IRS urges people who owe taxes, even if they have a filing extension, to carefully review their situation and pay what they can by July 15 to avoid penalties and interest.“The IRS understands that those affected by the coronavirus may not be able to pay their balances in full by July 15, but we have many payment options to help taxpayers,” said IRS Commissioner Chuck Rettig. “These easy-to-use payment options are available on IRS.gov, and most can be done automatically without reaching out to an IRS representative.”While the deadline for federal taxes remains on April 15, states may have different deadlines for their taxes. A list of state tax division websites is available through the Federation of Tax Administrators.Click here for more information from the IRS, including payment options. 1442
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