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President Donald Trump’s physical Dr. Sean Conley confirmed Friday that the president is taking an experimental antibody treatment to help him fight the coronavirus following his diagnosis this morning.Dr. Conley said Friday afternoon that Trump is "fatigued."Trump is taking the Regeneron antibody cocktail, which is currently in a clinical trial. Conley said that Trump has been treated with a single 8 gram dose, which Conley said was infused "without incident."Trump is also said to be taking Vitamin D, zinc, famotidine, melatonin and daily aspirin. The Regeneron trial has only been tried on 275 patients as of this week, but the company said earlier this week that it has showed promising results.Regeneron confirmed that Trump was given the treatment under a "compassionate use request.""In the USA, this type of compassionate use program is also known as an Expanded Access Program (EAP) and is intended for patients with serious or life-threatening conditions, who do not have any viable or available treatment options, and are unable to participate in ongoing clinical trials," Regeneron said in a statement. The plan is to enroll 2,000 patients in early studies of the treatment."After months of incredibly hard work by our talented team, we are extremely gratified to see that Regeneron's antibody cocktail REGN-COV2 rapidly reduced viral load and associated symptoms in infected COVID-19 patients," said George D. Yancopoulos, M.D., Ph.D., President and Chief Scientific Officer of Regeneron. "The greatest treatment benefit was in patients who had not mounted their own effective immune response, suggesting that REGN-COV2 could provide a therapeutic substitute for the naturally-occurring immune response. These patients were less likely to clear the virus on their own, and were at greater risk for prolonged symptoms.The treatment is a combination of two monoclonal and was designed specifically to block infectivity of SARS-CoV-2, the virus that causes COVID-19, the company said.“The two potent, virus-neutralizing antibodies that form REGN-COV2 bind non-competitively to the critical receptor binding domain of the virus's spike protein, which diminishes the ability of mutant viruses to escape treatment and protects against spike variants that have arisen in the human population, as detailed in Science.” Regeneron said in a statement. “Preclinical studies have shown that REGN-COV2 reduced the amount of virus and associated damage in the lungs of non-human primates.”According to Regeneron, the treatment has been tried on hospitalized and non-hospitalized patients and as a preventative for those who have had close contact with coronavirus patients. So far, the drug has been particularly promising for non-hospitalized patients.Regeneron said the treatment reduces the viral load from the coronavirus, and boosts the body’s immune response to the virus. 2890
RAMONA, Calif. (KGTV) — Poor road conditions and speed are being blamed for a solo-vehicle crash that left one person dead.California Highway Patrol said a Mitsubishi Montero was traveling northbound on State route 67, just north of Shady Bend, at about 6 a.m. Friday when it entered a slight curve on the roadway. Due to the vehicle's speed and the wet, partially icy roadway, the vehicle careened off the road and collided with a tree on the left side of the road, CHP said.RELATED: Video: Truck, school bus spin out on icy Interstate 8Interactive map: Winter storm coats Southern California in hail and snowThe driver, identified as a 43-year-old Spring Valley man, sustained major blunt force trauma and was pronounced dead at the scene by Ramona Fire Department officials. The man was wearing a seatbelt at the time of the crash and, at this time, alcohol or drugs are not considered a factor in the crash. He was not been identified pending family notification.CHP investigators were continuing to investigate the crash Friday. 1041

RAMONA, Calif. (KGTV) -- Authorities are searching for a person suspected in a deadly shooting in Ramona Thursday morning.The shooting was reported just before 6 a.m. in the 600 block of Pine Street, San Diego County sheriff's officials said. The reporting party told deputies they found a man on the ground in front of a neighboring home.The man was taken to a nearby hospital but did not survive. The man was not identified.Details on what led to the shooting remain unclear, but a sheriff’s official told ABC 10News the incident is being investigated as a homicide.With deputies searching on the ground, a law enforcement helicopter hovered over the area and announced a search for a male wearing a black hoodie. Drones were also used as part of the search.Deputies blocked state Route 78, between Olive Street and Haverford Road, due to the search.The manhunt was still underway as of 10:25 a.m.Anyone with information is asked to call the Sheriff's Homicide Unit at 858-258-6330/after hours at 858-565-5200, or Crime Stoppers at 888-580-8477.This story will be updated as more information becomes available. 1120
President Donald Trump's ex-wife Ivana doesn't think he should run for reelection in 2020. In an interview with Page Six, Ivana Trump said her ex-husband should instead enjoy his fortunes. “I’ll tell you something, I don’t think it’s necessary,” she told Page Six. “He has a good life and he has everything. Donald is going to be 74, 73 for the next [election] and maybe he should just go and play golf and enjoy his fortune."Ivana Trump was married to Donald from 1977 to 1992. The couple had three children: Eric, Donald Jr. and Ivanka. Despite being divorced for 26 years, Ivana remains in close contact with the President, saying they talk at least once a month. Ivana Trump believes her ex-husband probably misses some of the freedoms he had before entering the White House. "I don’t think he probably knew how much is involved of being the President," she told Page Six. "It’s so [much] information — you have to know the whole world.”Ivana Trump added during the interview that she feels for Trump's current wife Melania as speculation swirls around Trump's sex life, and his alleged relationship with porn star Stormy Daniels. "I feel bad for [Melania] because I know how bad I did feel. It hurts a lot,” she told Page Six.During their 15-year marriage, Ivana said she never suspected Donald of cheating on her. “Donald was always in the office and coming home, so I had no idea how he had the time to cheat,” she told Page Six. To see the full interview, click here. 1564
President Donald Trump tweeted a photo on Wednesday of rockets that were aimed at the US Embassy in Baghdad, and claimed that the rockets were fired by Iran.The attack came on Sunday, embassy officials confirmed. Trump said that three of the rockets failed to launch.The embassy said that there was minor damage to the compound, but no injuries. The US embassy said there were reports of damage and injuries in residential communities near the embassy.“These sorts of attacks on diplomatic facilities are a violation of international law and are a direct assault on the sovereignty of the Iraqi government,” the US Embassy in Baghdad tweeted.“Some friendly health advice to Iran: If one American is killed, I will hold Iran responsible. Think it over,” Trump said on Wednesday.Tensions rose earlier this year between Iran and the US after Iranian General Qasem Soleimani was killed after a US attack on the influential Iranian military leader. Iran responded by firing more than a dozen missiles that struck two airbases in Iraq that houses U.S. troops, the Pentagon confirmed. Iran said at the time that it did not seek to escalate tensions between the two nations."Iran took & concluded proportionate measures in self-defense under Article 51 of UN Charter targeting base from which cowardly armed attack against our citizens & senior officials were launched," Iran's Foreign Minister Javad Zarif said in January. "We do not seek escalation or war, but will defend ourselves against any aggression."Saeed Khatibzadeh, a spokesperson for Iran’s foreign ministry, alleged on Monday that the US was responsible for escalating tensions following Sunday’s attack.“We strongly refute Secretary (Mike) Pompeo 's irresponsible anti-Iran accusations, which blatantly aim to create tension,” Khatibzadeh tweeted. “Iran rejects any attack on diplomatic missions. The U.S. military presence is the source of instability in our region. No amount of spin can divert blame for its evils.” 1991
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