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CAMBRIDGE, Mass. – The U.S. government will pay Moderna Inc. up to .525 billion to secure 100 million doses of the company’s COVID-19 vaccine candidate.The U.S. Department of Health and Human Services (HHS) and Department of Defense (DoD) made the announcement Tuesday.HHS says Moderna will manufacture the vaccine doses while clinical trials are still underway to expedite the traditional development timeline and get vaccines to the public as soon as possible.The Trump administration hopes to deliver the vaccines by the end of the year, so long as the U.S. Food and Drug Administration (FDA) authorizes their use.“In creating a vaccine portfolio for Operation Warp Speed, the Trump Administration is increasing the likelihood that the United States will have at least one safe, effective vaccine by 2021,” said HHS Secretary Alex Azar. “Today’s investment represents the next step in supporting this vaccine candidate all the way from early development by Moderna and the National Institutes of Health, through clinical trials, and now large-scale manufacturing, with the potential to bring hundreds of millions of safe and effective doses to the American people.”HHS says the vaccine doses will be delivered to government-designated locations across the country and the U.S. could acquire up to an additional 400 million doses of the vaccine.If viable, the vaccines would be available to the American people at no cost, according to HHS. Healthcare professionals could charge for the cost of administering the vaccine, though.The vaccine, called mRNA-1273, has been co-developed by Moderna and scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The third phase of the vaccine trial, which began July 27, is the first government-funded Phase 3 clinical trial for a COVID-19 vaccine in the nation, according to HHS.“We appreciate the confidence of the U.S. government in our mRNA vaccine platform and the continued support,” said Stéphane Bancel, Moderna’s Chief Executive Officer. “We are advancing the clinical development of mRNA-1273 with the ongoing Phase 3 study being conducted in collaboration with NIAID and BARDA. In parallel, we are scaling up our manufacturing capability with our strategic partners, Lonza, Catalent and Rovi, to address this global health emergency with a safe and effective vaccine.” 2402

Carnival Cruise Lines announced Monday it will continue a suspension of operations in North America through the end of September amid the spread of the coronavirus.The cruise line’s decision takes its suspension well past a US government-mandated prohibition on cruises. The CDC issued a 100-day no-sail order on April 15, which is set to expire on July 24. It’s unclear whether the CDC will extend the order.Cruise ships became the site of several early outbreaks of the virus, causing passengers on board a number of ships to be quarantined as officials tried to determine how to safely allow passengers to disembark.The issue with outbreaks of COVID-19 have lingered on cruise ships as hundreds of crew members have remained quarantined on board ships for months.“Carnival is giving guests who wish to move their booking to a later date a rebooking offer that combines a Future Cruise Credit (FCC) and either a 0 or 0 Onboard Credit (OBC) that has proven very popular with their guests,” Carnival said in a statement. “Guests, as always, have the option to receive a full refund. The process is fully automated so that guests can submit their preference online and they have until May 31, 2021 to make a selection.”Whether Carnival is able to resume operations in October remains in doubt. Leading infectious disease experts expect cases in the fall to surge again. 1382

CARDIFF, Calif. (KGTV) - A pedestrian was struck and killed Saturday night in Cardiff after running across Interstate 5 and into the path of a car, authorities said.The incident happened just before 6:40 p.m. on the northbound lanes of the I-5 near Birmingham Drive, according to the California Highway Patrol.CHP officials said the pedestrian, a male in his 20s, was being transported via ambulance from Tri-City Hospital to the VA Medical Center when he suddenly jumped out of the vehicle. The ambulance was traveling between 50 to 60 mph, CHP said.The man survived the jump but proceeded to run across the southbound lanes. He hopped the center divide and was struck by a motorist traveling northbound.CHP said the man died in the collision.The motorist that struck the man remained at the scene and was cooperating with officers.A SigAlert was issued at about 7 p.m. for the three left lanes on northbound I-5. CHP reopened all lanes to traffic just before 9 p.m. 977

CAMP PENDLETON, Calif. (KGTV) - Hundreds of Marines recovering from injuries are at Camp Pendleton this week for the Warrior Games Trials. They're competing to represent the Marines at the National Games, but also finding new ways to heal from their injuries."It helps you know you're not alone," says Lance Corporal Jay Alan Davis, who was diagnosed with Major Depressive Disorder while on duty.This is LC Davis' first time at the games. He says it's been uplifting to find a sense of camaraderie among the athletes."If you're able to sit there and talk to somebody about it, they're more likely to go to you," he says. "Then you don't have to feel alone. You don't have to be alone."That's the same sentiment that brought Tisha Knickerbocker to the games in 2012. Tisha was a life-long athlete until she broke her back. Finding a way to compete still has helped her mental recovery."It improved everything," she says. "It was great. I really can't find a word that accurately describes the feeling that it gave me to get an old part of myself back."The games run from March 4-12 at Camp Pendleton. Many of the athletes will advance to the National Department of Defense Warrior Games in September in San Antonio. 1222

CARMEL, Ind. — Hundreds of people from all different faiths gathered at a Carmel synagogue to show their love for the Jewish community after someone left hateful anti-Semitic graffiti on one of their buildings. The ground was burned and swastikas and iron crosses were painted on a shed and garbage bins at Congregation Shaarey Tefilla on Saturday. RELATED: Anti-Semitic graffiti found at Carmel synagogueRabbi Benjamin Sendrow says the graffiti may have been left to evoke fear, but as Monday night's gathering showed, it's had the opposite effect on their community. "(It) triggered an outpouring of love and support that wipes away their action better than bleach and fresh paint," Sendrow said. "All they have done is awaken the sleeping giant of love and acceptance and mutual respect."But in the midst of love, those hateful messages also serve as a reminder that Indiana is one of only five states that doesn't have a hate crime law — something Indiana Gov. Eric Holcomb and several other lawmakers vowed to fix in the upcoming legislative session. Lindsey Mintz, Executive Director of the Indianapolis Jewish Community Relations Council, says passing that law is more important now than ever, to "send a message.""The state of Indiana from policy leaders on down will not stand for acts of hate based on bias," Mintz said.Synagogue leadership says the graffiti will not be cleaned off right away so it can be preserved as evidence as Carmel police continue to investigate and follow all leads to find out who is responsible.   1602