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As questions arise over when a coronavirus vaccine should be granted FDA approval, the leaders of several major pharmaceutical companies announced they have signed a pledge not to rush the development of a vaccine.The companies, AstraZeneca, BioNTech, GlaxoSmithKline, Johnson, Merck, Moderna, Novavax, Pfizer and Sanofi, released a joint statement on Tuesday confirming the pledge.The pledge includes the following points:Always make the safety and well-being of vaccinated individuals our top priority.Continue to adhere to high scientific and ethical standards regarding the conduct of clinical trials and the rigor of manufacturing processes.Only submit for approval or emergency use authorization after demonstrating safety and efficacy through a Phase 3 clinical study that is designed and conducted to meet requirements of expert regulatory authorities such as FDA.Work to ensure a sufficient supply and range of vaccine options, including those suitable for global access.There has been pressure on both the FDA and manufactures to develop and approve a vaccine for the coronavirus. There have been more than 190,000 coronavirus-related deaths in the US since March, and the economic impact of the virus has cost millions of jobs.While most developed countries have not had the same public health pain as the US, the economic impact of the virus has been felt worldwide. The International Monetary Fund estimates a nearly 5% loss in global GDP in 2020.In Russia, the country claimed to begin distributing a coronavirus vaccine despite US-based vaccine candidates likely being months away from being able to demonstrate efficacy.The pressure domestically has also ratcheted up as President Donald Trump has suggested a vaccine could be ready by this fall’s presidential election."We're going to have a vaccine very soon... maybe even before a very special date, you know what date I'm talking about,” Trump said on Monday.In late August, the CDC told states to begin to prepare distributing a vaccine by Nov. 1. But Surgeon General Jerome Adams said that just because states will be ready to help distribute a vaccine on Nov. 1 does not mean a vaccine will be ready by then."We've always said that we're hopeful for a vaccine by the end of this year or the beginning of next year,” Adams told Good Morning America."We want to make sure states are available to distribute it," he added.The companies signing on the pledge said that the FDA has strict protocols for vaccine candidates. A typical vaccine trial takes one to three years, but the companies believe only a safe and effective vaccine will be granted approval.“FDA has established clear guidance for the development of COVID-19 vaccines and clear criteria for their potential authorization or approval in the US,” the companies wrote in the pledge. “FDA’s guidance and criteria are based on the scientific and medical principles necessary to clearly demonstrate the safety and efficacy of potential COVID-19 vaccines. More specifically, the agency requires that scientific evidence for regulatory approval must come from large, high quality clinical trials that are randomized and observer-blinded, with an expectation of appropriately designed studies with significant numbers of participants across diverse populations.” 3296

Atlanta police released images late Sunday of a second person of interest in the fatal shooting of an 8-year-old girl on the Fourth of July. Authorities are also offering a ,000 reward for information in the death of Secoriea Turner. At least two shooters were believed to be responsible for her death. Police had released a short video of the first person of interest last week. Photos were released Sunday night of the second person of interest.According to Crime Stoppers in Atlanta, the preliminary investigation suggests the young girl was riding in a car with her mother and an adult friend when they were confronted by a group of people blocking the entrance to a parking lot. At some point, someone in the group opened fire on the car, hitting it several times and striking the child. The driver headed to a nearby hospital, and Turner died from her injuries. Both persons of interest are seen in the images carrying rifles. The fatal shooting happened near the Wendy's where Rayshard Brooks was shot and killed by a police officer. 1051

As protests reached unprecedented levels on Wednesday, bolstered by professional athletes sitting out sporting events, Republicans offered a full-throated backing of police officers during Night 3 of the Republican National Convention.Featured on Wednesday, Michael McHale of the National Association of Police Organizations, went after the Biden campaign, who he claimed is “anti-police.”“I’m proud that the overwhelming majority of American police officers are the best of the best and put their lives on the line without hesitation. And good officers need to know their elected leaders and the department brass have their backs,” said McHale.Meanwhile, unrest unfolded in Kenosha, Wisconsin, following the shooting of Jacob Blake. Blake was shot seven times by Rusten Sheskey, a Kenosha Police officer who has since been placed on administrative leave.Investigators, speaking for the first time since Sunday's incident, declined to press charges on Wednesday against Sheskey despite the massive protests. Joining in the protests were athletes from the NBA, MLB and MLS, who took the unprecedented step to boycott playing as players demanded action against the officer who shot Blake. As the fourth night of demonstrations ensued in Kenosha, amid a summer of protests demanding changes to policing, Sen. Marsha Blackburn, R-Tenn., decried protests.“I'm talking about the heroes of our law enforcement and armed services. Leftists try to turn them into villains. They try to cancel them. But I'm here to tell you that these heroes can’t be canceled.,” Blackburn said.Mike Pence, accepting the GOP nomination for a second term as vice president Wednesday, tried to thread the needle between offering support for law enforcement while understanding the pain many Black Americans are experiencing. "We don’t have to choose between supporting law enforcement and standing with African American neighbors," Pence said.While Republicans multiple times claimed that Biden would defund policing, Biden has said he opposes defunding police departments. 2052

At least 105 people are dead after an earthquake rocked the Indonesian island of Lombok over the weekend, state media reported Tuesday.Another 236 people have been injured in the quake, according to the government's disaster management spokesman Sutopo Purwo Nugroho, who told the Antara News Agency that the casualty numbers could rise as the search continued for survivors.More than 20,000 people have been displaced since the 6.9-magnitude quake struck Lombok, a popular tourist destination, on Sunday night.The epicenter of the earthquake was in northern Lombok, a more residential and less developed part of the island. Most of the tourist resorts are located on the southern side of the island.Most of those killed were struck by falling debris from collapsed buildings, according to Nugroho. Among the many buildings destroyed on Lombok were two homes which housed around 80 underprivileged children. 915

Authorities have identified the body of a young boy found at a New Mexico compound as Abdul-Ghani Wahhaj, a missing 3-year-old who was allegedly abducted by his father in November, according to the state's Office of the Medical Investigator.The boy's remains were discovered a few days after authorities first raided the makeshift compound earlier this month and discovered 11 emaciated children wearing rags and no shoes.Abdul-Ghani, who would have turned 4 the day his body was discovered, had been missing since last November, when his father, 40-year-old Siraj Wahhaj, allegedly took him from his mother in Jonesboro, Georgia, and said they were going to a park.They never returned.New Mexico authorities suspected the boy and his father were at the compound after learning about the abduction in May, according to the Taos County sheriff, but didn't have enough evidence for a search warrant. 915

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