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INDIANAPOLIS — The U.S. Food and Drug Administration on Monday granted emergency use authorization to Eli Lilly and Company's experimental COVID-19 antibody treatment bamlanivimab.According to a statement from the company, the drug is authorized for the treatment of mild to moderate COVID-19 in adults and pediatric patients 12 years and older with a positive COVID-19 test who are at high risk for progressing to severe COVID-19 and/or hospitalization. Lilly said in a statement the drug should be administered as soon as possible after a positive COVID-19 test and within 10 days of symptom onset. The authorization allows for the distribution and emergency use of bamlanivimab, which is administered via a single intravenous infusion."This emergency authorization allows us to make bamlanivimab available as a COVID-19 treatment for recently diagnosed, high-risk patients — adding a valuable tool for doctors fighting the now-increasing burden of this global pandemic," David A. Ricks, Lilly's chairman and CEO, said. "The rapid development and availability of bamlanivimab could not have been achieved without the relentless work of our Lilly team, collaboration across the industry and the urgent work being done by the government to ensure appropriate allocation to patients who need it the most."The emergency use authorization is based on data from BLAZE-1, a randomized, double-blind, placebo-controlled Phase 2 study in patients with recently diagnosed mild to moderate COVID-19 in the outpatient setting. Patients treated with the drug showed reduced viral load and rates of symptoms and hospitalization, Lilly said in the statement. Infusion reactions and other allergic hypersensitivity events have been reported, Lilly said. The emergency use authorization includes a warning for hypersensitivity including anaphylaxis and infusion-related reactions.Lilly said the drug is not authorized for use in patients who are hospitalized due to COVID-19 or who require oxygen therapy due to COVID-19 or who require an increase in baseline oxygen flow rate due to COVID-19 in those on chronic oxygen therapy due to underlying non-COVID-19 related comorbidity."The BLAZE-1 data show bamlanivimab, when given early in the disease course, may help patients clear the virus and reduce COVID-related hospitalizations, supporting our belief that neutralizing antibodies can be an important therapeutic option for patients fighting this virus," Daniel Skovronsky, M.D., Ph.D., Lilly's chief scientific officer and president of Lilly Research Laboratories, said. "We're proud of the speed with which we have been able to bring patients this therapy specifically designed to treat COVID-19. We thank those who have contributed to this medical advancement, particularly the clinical trial investigators and participants around the country." This article was written by Bob Blake for WRTV. 2906
Chris Hopkinson wanted to challenge himself, so he came up with a plan to paddle board the Chesapeake Bay. The whole Bay!"The physical mission was to paddle the bay; the real goal is to raise money for Oyster Recovery Partnership," he said.That goal of paddling 200 miles in 9 days was a daunting task."It's like a marathon everyday," he said.So with a goal of 20 to 30 miles a day, Hopkins took off from the Havre De Grace and headed down the bay to the Atlantic Ocean. He grew up around the bay but got a better understanding of it's beauty."When I'm coming down the Honga River and there's nobody around and there's just water and green and untouched beauty, you really get an appreciation for the beauty of the bay."Hopkinson knew this was going to be quite a physical challenge but Mother Nature decided to make it a little more interesting."Pretty high winds, 10 to 15 knots, which was creating some pretty good wave, 2 to 3 feet and then we had much cooler than normal temperatures."And that was the first day. Chris knew out of 9 days, not all were going to be good, but taking a punch in the face on the first day had him rethinking this adventure. He was motivated from those following his journey."I mean, I got hundreds of text messages and social media posts and emails from people just saying how much they were behind me and how excited they were. I think everybody really liked having a break from all the really bad news to follow something really good."So, on the 7th day he had heavy winds blowing from the side and head on and high waves and had to stop, his shortest day yet, 17 miles... 3 miles shy of goal for the day."I just couldn't take it."So, with that challenge from Mother Nature, what does he do the next day?"I took that day personally and the next day we had our best day which was 36 miles."And then just one day left, off he goes with a little encouragement from his wife, Megan.And he did get it done. Hopkinson raised 0,000 so far, right at their goal of 0,000. When a donation puts a thousand oysters in the bay, a marathon a day seems worth it. This story originally reported by "Disco" Don Harrison on WMAR2News.com. 2189
At a rally in Wisconsin Tuesday, President Donald Trump called on Gov. Tony Evers to "open it up" and claimed he "saved Kenosha" by sending in the National Guard.Trump spoke at a MAGA rally in West Salem, La Crosse County late Tuesday afternoon, exactly one week before Election Day.The president touched on two hot topics in the state: coronavirus, and protests and unrest in Kenosha following the police shooting of Jacob Blake."Speaking of lockdowns," Trump said after claiming Joe Biden wants to lock the country down to stem spiraling COVID-19 cases, "let's get your governor to open it up, get him to open it up." Evan Vucci/AP President Donald Trump speaks during a campaign rally at MotorSports Management Company, Tuesday, Oct. 27, 2020, in West Salem, Wis. (AP Photo/Evan Vucci) Trump moved on to protests and unrest in Kenosha."When the violent mob came to Kenosha - you know Kenosha, everybody knows Kenosha - Biden opposed sending in the National Guard. We sent in the National Guard, and we saved Kenosha. We saved Kenosha. Kenosha wouldn't be standing," Trump said at the La Crosse rally.Gov. Evers authorized Wisconsin National Guard members to deploy to Kenosha on Aug. 26, to assist local law enforcement. Biden vowed during his own visit to Kenosha that he will never exploit members of the National Guard for political purposes. Morry Gash/AP President Donald Trump speaks at a campaign rally Tuesday, Oct. 27, 2020, in West Salem, Wis. (AP Photo/Morry Gash) The president's rally Tuesday was his third in Wisconsin in the past two weeks. Trump attended a campaign event in Waukesha last Saturday and in Janesville the weekend before that. In early September, Trump visited Kenosha following protests and unrest.Prominent members of both the Trump and Biden campaigns have been ramping up their visits to the key battleground state ahead of Nov. 3, as some polls suggest the state will be won by slim margins, just like in the 2016 presidential election.This article was written by Jackson Danbeck for WTMJ. 2129
View this post on Instagram So, in light of changing times, @thestore_nashville is mobilizing delivery of a week’s groceries to our elderly neighbors in Edgehill and Berry Hill on Wednesday’s/Thursdays. If anyone needs to be included on this list, we urge them to contact info@thestore.org Also We will continue to operate regular hours 1-7 Th/F 11-5 Sat for walk ins but please bring ID and either proof of income, proof of residence, or statement of unemployment for our recently unemployed neighbors. #nashvillestrong A post shared by Brad Paisley (@bradpaisley) on Mar 17, 2020 at 12:41pm PDT 629
Former New Jersey Gov. Chris Christie remains hospitalized, but called a New Jersey newspaper editor from his hospital bed Monday morning, reportedly sounding raspy but not coughing — and fiery as ever.The former governor has struggled with asthma all his life, and announced on Twitter Saturday that he would check himself in to Morristown Medical Center on the advice of his doctors.Christie was seen outdoors in the White House Rose Garden hugging people without a mask last week. He also came in close contact with President Donald Trump and his staff when helping to prepare him for last week's debate."No one was wearing masks in the room when we were prepping the president during that period of time," Christie told Good Morning America. "The group was about five or six people in total."Monday, New Jersey Gov. Phil Murphy wished his predecessor a speedy recovery."He and I have had private communications," said Murphy. "He is in our prayers and he knows that we're here for him."The state is currently working to contact trace 206 people who attended a Trump fundraiser at his private golf club in Bedminster last week. Trump and his staff were there just hours before the president announced that he'd tested positive for COVID-19.The New Jersey Attorney General is now investigating whether the fundraiser violated state rules on social distancing. Many in attendance did not wear masks. But the Republican National Committee has insisted that face masks were provided and the event was in compliance.At Murphy's afternoon press briefing, he said the president and his staff acted recklessly by coming to New Jersey, knowing they had come in contact with someone who tested positive.“The actions leading up to and during this event have put lives at risk,” Murphy said.Some of the event attendees flew in from other parts of the country and have now scattered."This never should have happened," said the governor. This article was written by Christie Duffy for WPIX. 2002