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The fourth nor'easter in three weeks already is closing schools and canceling thousands of flights Wednesday as it's expected to dump record springtime snow in the Northeast.A day after the official beginning of spring, the storm will bring heavy snow, strong winds and even coastal flooding to some areas. It has potential to be one of the most significant and most disruptive snowstorms this late in the season, CNN meteorologists said."If the current forecast pans out, this nor'easter will dump more snow on Washington, Philadelphia and New York than the three earlier storms combined," CNN meteorologist Brandon Miller said.More than 70 million people are under a winter storm watch, warning or advisory from the southern Appalachians to Boston.The storm will move away from the region by Thursday but not without first hitting coastal New England and Maine.Latest developments? More than 4,100 flights are canceled Wednesday due to the storm, according to the tracking site Flightaware.com.? Public schools in New York City, Philadelphia and the District of Columbia are closed Wednesday.? The storm already dumped 13 inches of snow in Greencastle, Pennsylvania, and blanketed Smith Crossroads in West Virginia with 9.2 inches.Snow disrupting nation's capitalWashington will likely see 4 to 6 inches of snow, with some models hinting at much higher totals for the District. Areas west and north of the city are likely to see close to a foot of snow."It's been 75 years since Washington has had 5 inches of snowfall or greater this late in the season," Miller says.Track the storm with high resolution auto-updating graphicsThe inclement weather caused closures for much of the federal government. The White House and State Department canceled all public events for the day. However, the House and Senate are planning to work Wednesday as Congress tries to finalize a spending deal.Philadelphia could see up to a foot of snow. The City of Brotherly Love may get its biggest snowfall after the first day of spring in more than 100 years.For those in other parts of Pennsylvania, the storm was already well underway Wednesday morning. Thile Kreider posted an Instagram video of the snow blanketing her yard in Manheim.New York could break 1958 recordWind gusts and snow reached New Jersey and New York City on Wednesday morning. Ten inches to more than a foot is forecast in the New York City area before the storm departs early Thursday.But Central Park in Manhattan may only receive 4 to 6 inches of snow, CNN meteorologist Chad Myers said, explaining it's more likely snow will accumulate in areas at higher elevations."If New York gets 12 inches of snow -- the National Weather Service currently has a high-end potential of 13 to 21 inches -- it would be its largest snowfall ever recorded after the first day of spring," Miller says.The current record is 11.8 inches, set on March 21, 1958.With these late winter storms, it is difficult to predict snowfall amounts because of the mixing of warmer air. In some of the earlier nor'easters, the air near the ground has stayed warm enough that places like New York have seen lots of snow fall from the sky but had little accumulation. An urban heat island effect is plausible once again with this spring storm.Boston stayed on the warmer side in the first two nor'easters but then got walloped with snow during the third storm this month. The city is likely to see another 6 to 8 inches of snow, adding to the 20-plus inches it has already received in March.If Boston gets 10 inches, the city would have its third snowiest March on record.These late winter storms are likely to become more frequent with climate change. A study last week in the scientific journal Nature Communications ties extreme winter weather, specifically major snowstorms in the Northeast, to warming Arctic temperatures.Blizzard conditions likelyWith a forecast of heavy snow and winds more than 45 mph, blizzard conditions are possible.New York City could see sustained winds of 20 to 30 mph Wednesday, and coastal areas such as Cape Cod in Massachusetts are predicted to receive gusts up to 60 mph from midmorning Wednesday to Thursday.What is makes a snow storm a blizzardFlooding is a threat along the coast from Virginia to Massachusetts. Some of the worst coastal flooding could occur along the Jersey Shore, with high tides of 2 to 3 feet above normal possible.This will put a strain on already vulnerable coastal areas, which saw dramatic storm surges from the nor'easters over the last three weeks.The-CNN-Wire 4555

The Flores family has been farming dates for three generations.For the past few years, Marco Flores, owner of San Marcos Date Farm, says he’s seen major changes in temperature and weather patterns.“It’s drier than it used to be,” he said of the land his father bought in California’s Coachella Valley more than 55 years ago. “It used to be a lot more moist before.”These are conditions his 300 fruit-producing palm trees don’t like.“Sometimes there’s no rain,” Flores said. “The impact of climate change is definitely doing something to them.”Similar concerns are being expressed across the planet.“Climate change is impacting agriculture and farmers abilities,” said Paul Minehart of the Syngenta Group, a global agricultural innovation company.Minehart’s team recently published a study showing 72% of farmers they interviewed from around the world are worried about climate changes impacting crop yields.“It’s coming down to, especially in the United States, is the unpredictable weather patterns that are beginning to emerge,” he said.Minehart says those unpredictable weather patterns include unusual droughts and flooding in America and extremely arid conditions in other countries. Conditions that could impact farmers production and profits.“If you have fewer crops than the price could go up,” he said. “That could impact the overall cost of producing food and then at the consumer level buying the food.”Marco Juarez is the third generation of Flores farmers at San Marcos Date Farm.He says while using more water could cause his family to raise their prices from a pound for dates, there’s another growing concern: getting skilled workers to take a job in this heat.“I don’t think anyone really wants to work in this,” he said. “It slowly drives people away. I mean, who wants to be here in 120 degrees?” 1826

The Centers for Disease Control and Prevention's own medical advisers are criticizing the federal health agency for being slow to respond to a polio-like disease that's struck hundreds of children over the past six years."Frustrated and disappointed -- I think that's exactly how most of us feel," said Dr. Keith Van Haren, one of the CDC advisers on AFM and an assistant professor of neurology at the Stanford University School of Medicine.Van Haren and other doctors who care for these children say the agency has been slow to gather data and to guide pediatricians and emergency room physicians on how to diagnose and treat the children struck with the disease, acute flaccid myelitis."This is the CDC's job. This is what they're supposed to do well. And it's a source of frustration to many of us that they're apparently not doing these things," said Dr. Kenneth Tyler, a professor and chair of the department of neurology at the University of Colorado School of Medicine and another adviser to the CDC on AFM. 1022

The flower fields have been around for 50 years. The Flower Fields are owned and operated by the Ecke Family, the onsite grower and floral sales is handled by Mellano and Company. They share their passion for beauty and expertise inthe flower business, with a combined experience of 100 years.The Flowers Fields are known all over the world. There is no other place like it with over 50 acres of ranunculus flowers in 13 different colors. The flowers are delicate, its seed is tiny, paper thin, and smaller than an oat flake. The seed has to be mixed with water and sand, then it is placed in a cooler for two weeks to trick the seed into thinking it had a winter. Ranunculus do best in temperate climate. Morning fog, cool mornings, and temperatures in the 50s and 60s help the flower production. The flower fields are ecofriendly, they use a drip irrigation system. It places water exactly where the seed is, using the water needed and not more than that.Extreme temperatures can be costly and one of the biggest threats to the crop. Winter warm ups are less than ideal but too much rain is also bad. The team at the Flower Fields has learned to tackle the weather, but every year presents new challenges. This year they are expecting the best season yet, you can visit the Flower Fields through Mother’s Day weekend. Next year expect a new color to be added to the already beautiful fields. 1402

The Food and Drug Administration approved on Wednesday a treatment for the Ebola virus. This is the first FDA-approved treatment for Zaire ebolavirus infection in adults and kids.Zaire ebolavirus is one of four Ebola virus species that can cause potentially deadly infections. It is transmitted through direct contact with blood, tissue or body fluids of an infected person or wild animal.The treatment, Inmazeb, is a mixture of three monoclonal antibodies and was created by Regeneron Pharmaceuticals. The three antibodies work together to bind to the glycoprotein on the surface of the Ebola virus and block it from entry into the body’s cells.Inmazeb was tested in the Democratic Republic of the Congo during an Ebola virus outbreak in 2018-2019 through a partnership between the local government and the National Institutes of Health.A vaccine for Ebola virus was approved by the FDA in December 2019.Regeneron is also the company behind an experimental antibody cocktail that was given to President Donald Trump following his diagnosis of COVID-19, and which he said “cured” him. Trump was also prescribed the antiviral drug remdesivir and the steroid dexamethasone at the time.Regeneron’s COVID-19 treatment is a mix of two powerful antibodies that are believed to boost the immune response to the coronavirus. Early results seem promising, according to initial tests and a press release from the company.The company has submitted an application to the FDA to get emergency approval of their COVID-19 treatment. 1525

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