濮阳东方男科看病专业(濮阳东方妇科医院做人流手术可靠) (今日更新中)

WASHINGTON, Oct. 13 (Xinhua) -- U.S. researchers have corrected sickle cell disease in adult laboratory mice that had been bred to have the inherited blood disorder by activating production of a special blood component, according to a study published online Thursday in the journal Science.Sickle cell disease results from an abnormality in hemoglobin, the protein found in red blood cells that is responsible for transporting oxygen throughout the body. People living with sickle cell disease have two copies of an altered gene that produces sickle hemoglobin instead of normal adult hemoglobin. Sickle hemoglobin changes shape after releasing its oxygen, causing the red blood cell to become stiff, misshapen and sticky, and slowing blood flow to tissues. This process damages organs and causes pain.The study tested a new approach to increasing the production of a third form of hemoglobin -- fetal hemoglobin. Production of fetal hemoglobin predominates before birth, but turns off thereafter as adult hemoglobin production takes over. People with sickle cell disease are unable to make normal adult hemoglobin, and instead make sickle hemoglobin starting in infancy.An elevated level of fetal hemoglobin within the red blood cell reduces the tendency of sickle hemoglobin to change the shape of red blood cells. Considerable research has shown that the drug hydroxyurea increases production of fetal hemoglobin and reduces the number of pain crises and other complications of sickle cell disease in adults and children. However, not all patients respond well to hydroxyurea, and adverse side effects are a concern.The current study explores a more targeted approach to increasing fetal hemoglobin production. It builds upon earlier studies that discovered a protein called BCL11A normally suppresses the production of fetal hemoglobin soon after birth. The researchers viewed the BCL11A protein as a target for therapy and decided to see what would happen if they blocked production of the protein.The paper details how the research team silenced the mouse gene that produces the BCL11A protein in mice with sickle cell disease. Silencing the gene turned off production of the BCL11A protein and allowed the adult mice to continue to produce fetal hemoglobin. It appears to have eliminated disease symptoms without affecting other aspects of blood production."This discovery provides an important new target for future therapies in people with sickle cell disease," said Susan Shurin, acting director of the U.S. National Heart, Lung, and Blood Institute, which co-funded the study. "More work is needed before it will be possible to test such therapies in people, but this study demonstrates that the approach works in principle."Approximately 100,000 Americans live with sickle cell disease. It is most prevalent in people of African, Hispanic, Mediterranean, and Middle Eastern descent. There is no widely available cure for sickle cell disease. Bone marrow transplants have cured some patients, but the treatment is not without risk and most patients do not have relatives who can donate compatible and healthy bone marrow to them.

BEIJING, Dec. 12 (Xinhuanet) -- For many multinational firms, the past 10 years in China have not only marked the rise of the world's second-largest economy but have also been a decade of expansion and profit growth.As they look back at this "golden decade", which is often used to describe the days after China entered the World Trade Organization (WTO) in 2001, their early expectations and ambitions in a more liberalized Chinese market were found to be more than fulfilled.When German auto giant BMW set foot on the Chinese mainland by establishing its first office in Beijing in 1994, its products were still far too luxurious for ordinary Chinese.In 2001, only 6,500 vehicles were sold under the BMW and Mini brands in China.NYK Diana, a container ship, anchors at Qingdao Port in East China's Shandong province on Thursday, as workers load cargo.But sales started to pick up with China's WTO entry, when the removal of trade barriers brought unprecedented economic growth and a booming market.In 2010, the vehicle maker, which started a joint venture with the domestic Brilliance China Automotive in 2003, sold 169,000 vehicles in China.That record is set to be broken this year as more than 170,000 cars were sold only in the first three quarters."We are both beneficiaries and firm supporters of the open market system," said Christoph Stark, president and CEO of BMW's Greater China region.By liberalizing its market, China, which celebrated the 10th anniversary of its WTO accession on Sunday, has become a thriving market and a savior for foreign enterprises hit hard by the global downturn.In 2009, when General Motors declared bankruptcy in the United States amid the global recession, its Chinese branch saw sales rise 66.9 percent year-on-year to more than 1.8 million units.In 2010, China overtook the United States to become GM's largest national market.The list of similar companies is extensive, as China's decade-long membership of the WTO has helped the Asian powerhouse attract 347,000 foreign firms with investment of more than 0 billion in the past 10 years.Chong Quan, deputy representative for China's international trade talks, said foreign enterprises made more than 0 billion in profit in the 10-year period, with an average annual increase of 30 percent."The accession to the WTO has made China a more transparent, safe and predictable market, as well as an essential part of the global economy," said Dominique Poulique, president of Alstom China.The French power engineering and train company, with more than 30 entities and about 10,000 employees in China, is one of the major foreign suppliers to the Chinese rail transport market."Rapid changes took place in China in the past decade, with its massive investment in infrastructure construction and notable development in energy," Poulique said.Wang Zhile, director of the research center of transnational cooperation under the Ministry of Commerce, said increasing shared interests between China and multinationals are putting them into an inseparable community, one that has found win-win solutions in the past decade.There is also high-quality labor at a relatively low cost, including white-collar workers, he added.Admittedly, the huge market and rich resources have powered up multinational firms in global competition, especially during and after the financial crisis.Forty-nine percent of the responding multinational companies had higher expectations for China in the wake of the global financial crisis in 2008 and 2009, according to a recent survey by the Economist Intelligence Unit, a business information arm of the Economist Group.Although showing signs of a slowdown, China's economy is still widely expected to grow by more than 8 percent next year, at a time when debt and financial instability are weakening growth in other leading economies.Poulique said he expected China's rapid growth to continue into the next decade, especially in the infrastructure construction market."For Alstom, the top task here is to keep adapting to the changing business environment," he said.Many foreign companies are moving research and development facilities to China in the hopes of making it a base for talent and technology.In Shanghai, 347 multinationals have set up regional headquarters, with the establishment of 333 foreign-funded research and development centers.

BEIJING, Nov. 22 (Xinhuanet) -- Global AIDS deaths and new HIV infections have each dropped 21 percent since the peak of the AIDS pandemic in 1997, according to a UN report released Monday.One major factor responsible for the result is that life-saving HIV treatments have become more popular and got to 1.35 million more people in 2010 than in 2009.In middle-income and underdeveloped nations, these treatments have saved 2.5 million lives since 1995."We have seen a massive scale-up in access to HIV treatment, which has had a dramatic effect on the lives of people everywhere," said Michel Sidibe, executive director of the U.N. AIDS program.However, 53 percent of people who need HIV/AIDS treatments -- about 7.6 million people -- cannot get them, which accounted for 1.8 million AIDS deaths in 2010.There are now 34 million people living with HIV. And just in last year there were 2.7 million new infections.The decline in deaths and new infections means the AIDS pandemic is at a turning point, the UNAIDS report argues, adding smart investment can save millions of future deaths.

BEIJING, Jan. 05 (Xinhuanet) -- China's satellite television channels have aired fewer entertainment programs this year as broadcasting watchdog's curbs on "excessive entertainment" took effect.The State Administration of Radio, Film and Television has cut two-thirds of "racy" entertainment programs on China's 34 satellite channels since the campaign began, the spokesperson for the administration said on Tuesday.Since the regulation took effect on Jan 1, the total number of entertainment programs scheduled for prime-time -7:30 pm to 10 pm - broadcast a week dropped to 38 from 126 at the end of last year, according to a statement from the administration.Under the regulation, announced in October, each satellite channel can broadcast no more than two entertainment programs a week and the maximum length of the program may not exceed 90 minutes.The targeted programs, including dating shows, reality talent shows and emotional stories on the administration's list, were deemed "excessive entertainment" and showing "less taste"."Satellite channels should design programs with innovative content, promoting traditional virtues and socialist core values in their new entertainment programs," the authority said.The administration considers the move crucial to improving cultural content for the public by offering high-level programs.Meanwhile, the number of news programs on the satellite channels has grown to 193 a day, 33 percent more than in 2011.Currently, news programming on each satellite channel has surpassed two hours, and each channel has at least two 30-minute news programs during prime time.But popular dating shows such as If You Are the One, produced by Jiangsu Satellite TV, and reality shows such as China's Got Talent, aired by Shanghai-based Dragon TV, will remain on during prime time in the weekend.Li Hao, spokesman for Hunan Satellite TV, a broadcaster famous for its entertainment programs, told China Daily the regulation will improve the quality of entertainment programs."We have been exploring how to make entertainment shows more meaningful and valuable," he said, adding that the channel has shortened the length of its two entertainment programs from 110 to 90 minutes."We will supervise programs more strictly, and pay close attention to things such as the clothing and comments of hosts and guests," he added.Cheng Manli, a media professor at Peking University, welcomed the new regulation to limit "less tasteful" programs involving violence and money worship."After all, unhealthy programs may hurt young people who are not able to distinguish right from wrong, which also worries their parents," she said.However, Yu Guoming, a professor at the School of Journalism at Renmin University of China, did not think the regulation was the way to improve cultural development."Whether the entertainment program is good or not should be decided by viewers' reaction, instead of an administration's evaluation," he said. "Residents are under pressure and need to watch shows to relax in our society."Yu also said that a good entertainment program should respect residents' taste and give them more viewing choices, or else it could lead to rigid restrictions.Ma Yuqiang, who runs an online clothing retail company, said the new rule will not affect his daily life, because he can watch the entertainment programs that were taken off prime time on the Internet."I think the regulation will drive most young people to the Internet," Ma, 26, said.

来源：资阳报