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State officials said dry conditions and strong winds have combined to create potential fire dangers."These fires are going to continue to be quite explosive under these conditions, with that kind of wind pushing it, and all the dry fuels that are available," Finch-Walker told CNN. "The fire is rapidly spreading and growing and we will continue to see extreme fire behavior until we can get through this event.""We've got historic conditions as far as fire. We haven't seen these kinds of conditions in a decade," said Matt Lehenbauer, emergency management director for Woodward County."We've had half an inch of rain in six months," Lehenbauer said.Gusts were expected to pick up Friday, which could lead to additional evacuations as winds could "push the fire into more populated area," Lehenbauer said.State Highway 34 was closed at the US-60 junction at Vici south to Camargo because of fire conditions. Both lanes of westbound I-40 were closed at Erick because of fires in Texas. Motorists traveling to Texas were advised to not travel any farther than Elk City.The fires' spread comes as the United States faces a trio of dangerous weather possibilities this weekend: Besides the critical fire danger in Oklahoma and the Southern Plains, severe storms and tornadoes are forecast in the Mississippi River Valley, and heavy snow is expected for the Northern Plains and Upper Midwest.Clarification: There is one fire in Dewey County, Oklahoma, where the town of Vici is located. 1482

Supporters of right-to-try argue that the legislation is needed because most terminal patients are too sick to be selected to participate in clinical trials and it takes too long for promising treatments to be approved.Joffe argued that the right-to-try approach to providing access to unapproved drugs early in their development could put patients in harm's way, as patients receiving the drug are often in very fragile health, doctors often lack the information needed to administer the drugs safely, and little may be known about their risks and benefits, he said.Joffe pointed to certain stem cell therapies as treatment approaches that appear promising but have turned dangerous when unregulated."Another thing I'm worried about is that there's going to be a bunch of shady actors that are going to pop up that are going to start to try to take advantage of the right-to-try law to say 'we can provide these sort of experimental therapies, if you want to call them that, to patients without needing to go through the FDA,'" Joffe said."We've already seen some of that in the stem cell clinics popping up around the country that try to provide stem cell treatments for a host of problems: eye problems, heart problems," he said. "While there are legitimate efforts to develop effective stem cell therapies, a lot of these clinics that are popping up around the country that are poorly regulated are taking people's money and they are hurting people."On the other hand, the treatments available under right-to-try laws are already in clinical trials, Coleman said, adding that "this law isn't replacing the existing FDA expanded access program; it's just opening up another avenue.""No person is going to be forced to take an investigational drug. No doctor is going to be forced to request an investigational drug, and no drug company is forced to provide an investigational drug, if they don't think it's the right fit for a patient," she said."It's only for people who say, 'I understand the risk. I know this drug is not fully approved. It may not help me, but my doctor and the drug company think it could, and I want to try,'" she said. "Basically, if the FDA says that a drug is safe enough to be used in trials on humans, then it's safe enough for a dying person to make their own choice about whether or not they would like to try it when they can't get into a clinical trial."  2395

Shoots said, “The spark has to be in the right spot and sometimes the conditions line up. And it can be the worst-case scenario and they aren’t. We catch some breaks and we are able to get in there and have resources in these fires.”Even though the numbers are down, Cal Fire wants everyone to stay vigilant and stay fire ready because fire season is far from over. 365

Smaller ceremonies and remembrances will also be held throughout the day. At 5:46 a.m., U.S. Customs and Border Protection will temporarily close the Otay Mesa and San Ysidro ports of entry for roughly 10 minutes to honor the victims of the attacks.In addition, prior to the San Diego Padres' 7:10 p.m. game against the Chicago Cubs, the team will hold a salute to local first responders and a ceremony to honor the victims of the attacks. 439

Some saw the memo as a direct affront to Kushner, who has had access to highly classified information for over a year but still does not have a permanent security clearance. Kushner is one of the few White House officials who regularly receives the President's Daily Brief, a daily roundup of issues that the intelligence community determines the President needs to be aware of each morning. 391

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