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SAN DIEGO (KGTV) -- We’ve known for a while that COVID-19 hits people over 65 especially hard, but a study published Wednesday from researchers in San Diego offers new insight into why that happens.The numbers are staggering: if you’re 65 or older, your risk of winding up in the hospital from COVID-19 is five to 11 times higher than someone under 30. Your risk of death is at least 90 times higher, according to data from the Centers for Disease Control and Prevention.Researchers at the La Jolla Institute for Immunology say the reason why older people fare so much worse appears to be from a lack of T-cells, a type of white blood cell that can decline with age.“Some viruses get controlled by one part of the immune system. Some viruses get controlled by another. In this case it seems that T-cells really do a lot of the work,” said Dr. Shane Crotty, one of the authors of the study published Wednesday in the journal Cell.Dr. Crotty and his colleagues looked at 50 people infected with the virus, and they measured the three elements of the adaptive immune system in detail: antibodies, helper T-cells and killer T-cells.Then they compared the measurements to how people fared against the virus. Some patients in the study group had severe cases, others had mild infections.The researchers found that people with all three branches of the adaptive immune system tended to fully recover. People with severe cases of the virus often lacked one or more of the immune branches, and it was particularly evident in older people.“Our data indicated that of the older individuals, it was particularly the ones that had fewer T-cells to start that look like they really struggled to control this virus,” Dr. Crotty said.As we age, we have fewer T-cells to send after invading pathogens. “That collection of T-cells gets smaller. So it’s harder to recognize a new virus,” Crotty said.Among the 748 deaths in San Diego County reported as of Wednesday, 87% were people aged 60 and older.The findings from LJI may have implications in the search for a vaccine against COVID-19. The data suggests that vaccine-makers may want to target a drug that elicits all three branches of the immune response, Dr. Crotty said. Some vaccine approaches, such as inactivated virus vaccines, only elicit two of three branches, not killer T-cells. However, Crotty said it was too soon to rule any candidates. Two strong branches produced by a vaccine could potentially cover for the lack of a third, he said.Crotty said the findings could help vaccine-makers interpret results from the clinical trials and find the right dosing.“Is a given vaccine a good vaccine, and you just need a booster immunization?” he said. “Does it work well in one population but it doesn’t help in the elderly because it doesn’t generate a T-cell response, for example? Those are the scenarios when this type of knowledge will come into play.” 2906
SAN DIEGO (KGTV) — Two people escaped uninjured after a sailboat crashed into an Ocean Beach jetty, before the vessel itself was crushed by high surf.The 25-foot long boat collided into the North Channel jetty in Ocean Beach with the two individuals on board, according to San Diego Fire-Rescue Department spokeswoman Monica Mu?oz. San Diego Lifeguards used a personal water craft to reach the vessel and safely pull the two individuals after they were forced to jump from the boat. The boat was attempting to leave the jetty area when a large wave forced them to pull a U-turn. SAN DIEGO FORECAST: Wednesday's rains to strengthen heading into ThursdayWind caught the sails and instead sent the vessel back into the jetty, according to witnesses at the scene.Those two people were uninjured in the wreck though the sailboat was crushed by high surf and sunk within the channel's entrance, according to Mu?oz.The boat's owner is now responsible for making arrangements to tow the boat from the channel.RELATED: Where to get free sandbags to protect your home from floodingA storm system forecasted for San Diego County has brought high sets to local beaches Wednesday. High surf forced the Ocean Beach Pier to close and lifeguards to ask swimmers to stay out of the water, as waves could be seen crashing against the pier. 1329

SAN DIEGO (KGTV) — Who said vinyl was dead?April 13 marks Record Store Day (RSD) in the U.S., as stores across the country plan to take part in the celebration of records with special releases.Releases from artists including Bob Dylan, David Bowie, Foo Fighters, Prince, Sly & The Family Stone, Weezer, and many more will hit record store shelves for the musical holiday. RELATED: Wonderfront to bring 70 bands, three-day festival to San Diego waterfrontThis year's RSD ambassadors, Pearl Jam, will also have a special release available, according to the organization Record Store Day, which promotes the day every April as well as independent record stores year-round.A full list of RSD releases can be found here.In San Diego, several local stops are celebrating with the special RSD releases — and there are plenty of other stops to visit to support independent retailers:Spin Records - 370 Grand Ave., Carlsbad (p)Lou's Records - 434 North Coast Highway 101, Encinitas (p)Gary's Record Paradise Vol. II - 1911 Sunset Dr., Suite 5, EscondidoThe Old Well - 2102 3rd St., JulianRed Brontosaurus Records - 9500 Gilman Dr., La JollaCow - 5040 Newport Ave., San Diego (p)FeeLit - 909 E St., San Diego (p)Five Space Shop - 2579 University Ave., San DiegoFolk Arts Rare Records - 3072 El Cajon Blvd., San Diego (p)M-Theory - 827 W. Washington St., San Diego (p)Nickelodeon Records - 3335 Adams Ave., San Diego (p)Normal Records - 4201 30th St., San Diego (p)Record City - 3757 Sixth Ave., San Diego (p)Taang! Records - 3830 5th Ave., San DiegoThe Vinyl Room - 3333 Midway Dr., Suite 105, San DiegoVinyl Junkies Record Shack - 2235 Fern St., San Diego (p)Old Town Records - 42012 Main St., Temecula (p)Spindles Music Shack - 27519 Ynez Rd., Temecula (p)Stores with a (p) signify they plan to sell commercial Record Store Day releases to customers, according to RecordStoreDay.com.Some local shops will not only offer up special record releases, but live entertainment too.Vinyl Junkies plans to host a live DJ set by LOL Tolhurst, former drummer for The Cure, and other DJs. Live music from other artists, including Rob Crow, Systems Officer, and Mario Rubalcaba is also scheduled.M-Theory Music will also celebrate Record Store Day with live in-store performances by Nate Legend, Ariel Levine, Thnuderegg, Tape Waves, and more. The first 250 people in line also get a free tote bag. 2391
SAN DIEGO (KGTV) — Two people escaped uninjured after a sailboat crashed into an Ocean Beach jetty, before the vessel itself was crushed by high surf.The 25-foot long boat collided into the North Channel jetty in Ocean Beach with the two individuals on board, according to San Diego Fire-Rescue Department spokeswoman Monica Mu?oz. San Diego Lifeguards used a personal water craft to reach the vessel and safely pull the two individuals after they were forced to jump from the boat. The boat was attempting to leave the jetty area when a large wave forced them to pull a U-turn. SAN DIEGO FORECAST: Wednesday's rains to strengthen heading into ThursdayWind caught the sails and instead sent the vessel back into the jetty, according to witnesses at the scene.Those two people were uninjured in the wreck though the sailboat was crushed by high surf and sunk within the channel's entrance, according to Mu?oz.The boat's owner is now responsible for making arrangements to tow the boat from the channel.RELATED: Where to get free sandbags to protect your home from floodingA storm system forecasted for San Diego County has brought high sets to local beaches Wednesday. High surf forced the Ocean Beach Pier to close and lifeguards to ask swimmers to stay out of the water, as waves could be seen crashing against the pier. 1329
SAN DIEGO (KGTV) - Huey Lewis and The News fans disappointed by the band’s canceled concerts have a chance to enjoy its hit songs at a musical, Heart of Rock and Roll, set to debut at San Diego’s Old Globe Theatre in September.Lewis, the band’s lead singer and namesake, announced Friday he was dealing with the sudden loss of his hearing."Two and a half months ago, just before a show in Dallas, I lost most my hearing," Lewis said in a message to his fans Friday. "Although I can still hear a little, one on one, and on the phone, I can't hear music enough to sing."Lewis went on to explain that doctors believe he has the inner ear disorder Meniere's disease and said he should not perform until he improves."Needless to say, I feel horrible about this, and wish to sincerely apologize to all the fans who've already bought tickets and were planning to come see us," Lewis added. "[I] hope that one day soon I'll be able to perform again."Fans will be able to hear the 80s rocker’s hits in Heart of Rock and Roll, which runs September 6 through October 21. The show will feature the band’s hit songs, including “The Power of Love”, “Hip to Be Square”, and “If This Is It”. Lewis made the announcement with the help of Jimmy Kimmel.“Huey’s talent has drawn a brilliant team of theatrical visionaries together, led by the witty and imaginative director Gordon Greenberg, and they’ve made a musical that’s about as great a night out as I can imagine. I can’t wait to share it with San Diego’s audiences,” said Erna Finci Viterbi Artistic Director Barry Edelstein.Anyone who already purchased tickets to the canceled concerts via credit card will receive an email with refund details. If you purchased your tickets via cash or check, you'll have to bring your original tickets to the point of purchase for a refund. 1852
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