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The Trump Administration pushed through a million contract to study whether the active ingredient in Pepcid is an effective treatment for Covid-19. That contract is now under scrutiny after a government whistleblower accused a senior administration official of rushing the deal through without the scientific oversight necessary for such a large federal award. The Food and Drug Administration gave the clinical trial speedy approval even as a top agency official worried that daily injections of high doses of famotidine for already sick patients pushed the levels of what was considered safe “to the limits,” internal government emails show. And the doctors who initially pushed the Pepcid idea are locked in a battle for credit and sniping over allegations of scientific misconduct.The origins of the interest in famotidine are under dispute, but there were reports out of China that patients who took the drug survived the virus, while patients who took other heartburn medications were not surviving. Initial observational studies in the U.S. were promising, however scientists urged more research was needed. Meantime, the trial itself that was part of the million contract is on pause due to a shortage of hospitalized COVID-19 patients in New York, delaying it indefinitely. A vaccine or effective treatment could be available before the study is complete. 1380

The teenager who allegedly used a shotgun and a revolver to kill 10 people and wound 10 others at a Texas high school Friday admitted he didn't shoot people he liked and meant to kill the ones he did target, a probable cause affidavit says.Suspect Dimitrios Pagourtzis, 17, has cooperated with police, said Galveston County Magistrate Mark Henry said. Henry denied bail for the student, who is accused of capital murder of multiple people and aggravated assault on a public servant.Students at Santa Fe High School, not far from Houston in southeastern Texas, scrambled for safety after they heard shots just after class began Friday morning. Nine students and one teacher were killed, a law enforcement official told CNN.Pagourtzis said little during a video court appearance, answering "Yes, sir" when asked whether he wanted a court-appointed attorney. He was not asked to enter a plea.The probable cause affidavit says he told an investigator he spared people he liked because he wanted his story told.The alleged shooter used a shotgun and a .38 revolver that were legally owned by his father, Gov. Greg Abbott told reporters. Two school resource officers were on the campus and confronted the shooter "early on in the process," Abbott said.Live updates on the school shootingLatest developments? A student who survived being shot in the head tweeted: "I'm so greatful and blessed that god spared me today." Rome Shubert showed CNN affiliate KTRK where a bullet went in the back of his head and came out near his left ear.? A Pakistani exchange student, Sabika Sheikh, was killed, the county's embassy in Washington said.? One classmate told CNN the alleged shooter was "really quiet and he wore like a trench coat almost every day."? Abbott said investigators have found journals on a computer and cell phone owned by the suspect.? The governor offered his sympathies to the victims then called for lawmakers and others to come together to prevent more tragedies. "We need to do more than just pray for the victims and their families. It's time in Texas that we take action to step up and make sure this tragedy is never repeated ever again."? Retired Houston Police officer John Barnes was one of the people shot at Santa Fe High School, a hospital official said. Houston's police chief tweeted that he visited the hospital where Barnes was being treated and that Barnes was "hanging in there." The officer was working as a Santa Fe officer, a police union official tweeted.What we know about the shootingEarly morning attackGunfire erupted at the school, about 20 miles outside Galveston, not long after classes began around 7:30 a.m. CT, officials said. Authorities later found explosive devices -- including pipe bombs and pressure cookers -- in and near the school, the law enforcement official said.The suspect is believed to be a student. A second person -- also believed to be a student -- has been detained as well, Harris County Sheriff Ed Gonzalez said earlier.The male that Gonzalez described as a suspect was injured, a law enforcement official said on condition of anonymity.Investigators believe that the second person, an 18-year-old, may be an accomplice but not a shooter, a law enforcement official said.Two law enforcement officers are among the injured, according to a law enforcement source.One man is in critical condition with a gunshot wound in one of his arms, said David Marshall, chief nursing officer for University of Texas Medical Branch hospital.This is the 22nd US school shooting since the beginning of the year, and the third instance in eight days in which a gunman was on a school campus.Witnesses described students running from the school as they heard gunshots; they also described hearing an alarm at the school, though the sequence of events wasn't immediately clear.Authorities found explosive devices in the high school and in adjacent areas, said Walter Braun, Santa Fe Independent School District police chief. It wasn't immediately clear if any had exploded.Because the devices were found, Braun urged people in the city of about 13,000 people to "not touch any items that look out of place, and call 911" if they see something suspicious.Investigators Friday afternoon were searching a trailer where they believe the devices were assembled, a law enforcement source said.The school has been cleared of all students and staff, who have been directed to a nearby facility to reunite with their families, Braun said.Witness: Shooter fired gun in an art classAn armed person walked into an art class at the school and began firing what looked like a shotgun, a witness told KTRK.The witness told KTRK she saw a girl shot in the leg.Victims were being treated at three hospitals, authorities said. Eight people went to Clear Lake Regional Medical in Webster, Texas; two patients were treated at Mainland Medical Center in Texas City; and four patients went to John Sealy University of Texas Medical Branch in Galveston. It is unclear whether they were all wounded.Six of the eight patients at Clear Lake Regional were discharged by Friday afternoon.Witnesses describe hearing an alarm as well as gunfireAngelica Martinez, a 14-year-old student, told CNN she and her schoolmates were being evacuated at one point "like it's a fire drill.""We were all standing (outside), but not even five minutes later, we started hearing gunshots," she said. "And then everybody starts running, but, like, the teachers are telling us to stay put, but we're all just running away.""I didn't see anybody shooting, but like (the gunshots) were kind of spaced," Angelica said, adding she heard about four shots.A witness who spoke to KTRK also said she heard an alarm. She didn't specify if that was before or after the gunfire she described in the art class.She said she couldn't describe the shooter."I didn't look. I just ran," she said.Another student, Dakota Shrader, told CNN affiliate KPRC that she heard gunshots only after hearing an alarm in the school."I was in the history hallway, and as soon as we heard the alarms, everybody just started leaving following the same procedure as ... (a) practice fire drill," Shrader said, breaking into tears. "And next thing you know, we just hear ... three gunshots, loud explosions, and all the teachers are telling us to run."MaKenna Evans, a 16-year-old sophomore, told CNN she was in geometry class when the shooting started.First, she heard a fire alarm, she said. When the students got outside, her principal told them all to run.Evans said students hid behind a building across the street from the school.The high school has about 1,400 students, according to GreatSchools.org.Trump: Mass shootings have been 'going on too long in our country'Trump addressed the school shooting, saying that mass shootings have been "going on too long.""Unfortunately, I have to begin by expressing our sadness and heartbreak over the deadly shooting at Santa Fe High School in Texas," Trump said from the East Room of the White House. "This has been going on too long in our country. Too many years. Too many decades now."Trump said federal authorities are coordinating with local officials."We grieve for the terrible loss of life and send our support to everyone affected by this absolutely horrific attack," Trump said.Trump has ordered US flags at federal facilities be flown at half-staff.The-CNN-Wire 7385

The Trump administration is extending a ban on green cards issued outside the United States until the end of the year and adding many temporary work visas to the freeze, including those used heavily by technology companies and multinational corporations. The administration is casting the effort as a way to free up jobs in an economy reeling from the coronavirus. A senior official who spoke to reporters on condition of anonymity estimated the restrictions will free up to 525,000 jobs for Americans. Through the first 60 days of the program, the senior administration official said the White House projects that the visa ban saved around 50,000 American jobs, but could not specify the type of jobs. The ban does not impact refugees or people already in the United States, a senior official said. The ban, while temporary, would amount to major restructuring of legal immigration if made permanent. 909

The Supreme Court will allow absentee ballots in North Carolina to be received and counted up to nine days after Election Day, in a win for Democrats. The justices on Wednesday refused to disturb a decision by the State Board of Elections to lengthen the period from three to nine days, pushing back the deadline to Nov. 12. The board’s decision was part of a legal settlement with a union-affiliated group. Under the Supreme Court’s order, mailed ballots postmarked on or before Election Day must be received by 5 p.m. on Nov. 12 in order to be counted.The decision stands in contrast with a decision made by the Supreme Court earlier in the week not to extend the deadline in Pennsylvania for the state to count mail-in ballots received after Election Day. 766

The Seattle City Council unanimously approved a law on Tuesday that will raise the minimum pay for Uber and Lyft drivers.In a statement on the Seattle mayor's website, Mayor Jenny Durkan celebrated the city council passing her Fare Share Plan that would make ride-hailing companies pay their drivers the minimum hourly wage, which will go into effect Jan. 1, 2021."The pandemic has exposed the fault lines in our systems of worker protections, leaving many front line workers like gig workers without a safety net," Mayor Durkan said. "It is more important than ever that we add to the economic resilience of our community of drivers. The Fare Share plan guarantees that drivers will receive fair pay and can provide for themselves and their families."The ordinance guarantees drivers will earn at least <云转化_句子>.56 per minute and .33 per mile driven while transporting passengers.The measure uses a formula for drivers' compensation so they would be paid fairly when they're less busy. 994