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WASHINGTON, April 25 (Xinhua) -- The U.S. National Aeronautics and Space Administration (NASA) and the U.S. Agency for International Development (USAID) have agreed to expand their joint efforts to overcome international development challenges such as food security, climate change, and energy and environmental management.NASA Administrator Charles Bolden and USAID Administrator Rajiv Shah signed a five-year memorandum of understanding on Monday, at NASA Headquarters. The agreement formalizes ongoing agency collaborations that use Earth science data to address developmental challenges, and to assist in disaster mitigation and humanitarian responses. The agreement also encourages NASA and USAID to apply geospatial technologies to solve development challenges affecting the United States and developing countries."Technologies for NASA missions have long improved life here on Earth. Together with USAID, we'll meet even more sustainable development challenges here on the ground, solving problems for the world community," Bolden said in a statement. "As we explore space, we'll also be exploring solutions to important health, nutritional and safety challenges in developing countries."The agencies will continue collaborations to stimulate innovative science and technology solutions to international development challenges by using Earth science data, research results, computer models, visualization applications and remote- sensing techniques.USAID is the lead federal development agency implementing U.S. development efforts through field-based programs and projects around the world. NASA has broad experience with Earth science research, development of Earth science information products, and technology applications."Through our partnership with NASA, we can apply the latest, cutting-edge technology to deliver meaningful results for people in developing countries in areas like health, food security and water," Shah said. "It's a prime example of our efforts to use the power of science and technology to tackle today's pressing development challenges."Since 2003, NASA and USAID have worked together building and expanding the SERVIR program, which allows people in developing regions to use Earth observations for addressing challenges in agriculture, biodiversity conservation, climate change, disaster response, weather forecasting, and energy and health issues.The agencies also collaborate on the LAUNCH program, which supports science and technology innovators in the nonprofit and private sectors. The program's goal is improving innovations to achieve greater impact on sustainability issues.

WASHINGTON, April 6 (Xinhua) -- A study led by researchers at the University of Michigan (U-M) showed in animal studies that new cancer drug compounds they developed shrank tumors, with few side effects.The study, done in two mouse models of human cancer, looked at two compounds designed to activate a protein that kills cancer cells. The protein, p53, is inactivated in a significant number of human cancers. In some cases, it is because another protein, MDM2, binds to p53 and blocks its tumor suppresser function. This allows the tumor to grow unchecked. The new compounds block MDM2 from binding to p53, consequently activating p53."For the first time, we showed that activation of p53 by our highly potent and optimized MDM2 inhibitors can achieve complete tumor regression in a mouse model of human cancer," says lead study author Shaomeng Wang, director of the Cancer Drug Discovery Program at the U-M Comprehensive Cancer Center.Wang presented the study Wednesday at the American Association for Cancer Research 102nd annual meeting.Many traditional cancer drugs also activate p53 but they do so by causing DNA damage in both tumor cells and normal cells, causing side effects. These new MDM2 inhibitors activate p53 while avoiding the DNA damage common with other drugs. In this study, which was done in collaboration with Ascenta Therapeutics and Sanonfi-Aventis, researchers showed that these new drugs shrank tumors without significant side effects.Because p53 is involved in all types of human cancer, the new drug has potential to be used in multiple types of cancer. Further, the researchers also identified certain markers in tumors that predict which ones will be particularly sensitive to the MDM2 inhibitor, which would allow physicians to target the drug only to patients most likely to benefit.

BEIJING, Feb. 27 (Xinhua) -- A total of 2.64 billion trips in China were recorded by road or ships during the 40-day Spring Festival transportation season which ended Sunday, the Ministry of Transport said.The figure was 13.6 percent higher than the same period last year, noted ministry spokesman He Jianzhong.To ensure smooth transportation, 840,000 buses were put into use each day during the busy season, as well as 13,089 ships, He said.Statistics on railway transportation are not yet available.However, statistics from the Beijing railway administration showed 20.63 million tourists had left Beijing during the transportation season from Jan. 19 to Feb. 27, up 3.9 percent year on year.The busy Spring Festival transportation season runs for 40 days and is calculated in two phases: 15 days before and 25 days after the Spring Festival.

ACCRA, Feb. 12 (Xinhua) -- China would in the coming years inject more capital to support the infrastructure needs of Ghana, Chinese Ambassador to Ghana Gong Jianzhong has said.Briefing the media here on Friday night to announce the visit to Ghana by Chen Deming, the Chinese Minister of Commerce, Ambassador Gong said that China is willing to join in the infrastructure development of Ghana."We are willing to join Ghana in improving its infrastructure base. We will be happy to give our contribution towards the infrastructure development of Ghana," he said.The forthcoming two-day visit by the Chinese minister would afford the two countries to further cement, promote and syncretize the bilateral trade and economic corporation existing between them for more than five decades.The ambassador said the Chinese Embassy in Ghana is committed to offering quality service to Ghanaians engaging in bilateral exchanges and cooperation in different fields.Currently, China has supported the West African country in the construction of various roads, rails, school blocks, hospitals, among others.He called on the Chinese firms in Ghana to raise investments and take corporate social responsibilities in local communities where they are operating.

You can think of NASA's Discovery program as a sort of outer-space American Idol: every few years the agency invites scientists to propose unmanned planetary missions. The projects have to address some sort of fundamental science question, and (this is the tough part) they have to be relatively cheap to pull off — say, half a billion dollars or so. Then the proposals go through a grueling competition before judges who aren't as nasty as Simon Cowell but who are every bit as tough. The one left standing at the end gets the equivalent of a recording contract: NASA supplies the funding and the launch vehicle, and away the winner goes — to orbit Mercury, as the Messenger spacecraft is doing right now; or to rendezvous with a couple of asteroids, as the Dawn mission will start doing this July; or to smash into a comet on purpose, a feat achieved by Deep Impact in 2005, a mission not to be confused with the movie of the same name. Now it's time for the next contenders. NASA has just announced that the first round of the latest Discovery competition is over, with three entries out of 28 moving on to the finals. They are, in increasing distance from Earth: the Geophysical Monitoring Station (GEMS) lander, which would use seismometers to study the interior of Mars; the Comet Hopper, which would do just that, leaping from place to place across the surface of Comet 46P/Wirtanen to see how different parts of the tumbling body react to heating by the sun; and the Titan Mare Explorer (TiME), which would plop into a sea of liquid hydrocarbons on Saturn's moon Titan — the first oceangoing vessel ever to set sail on another world. If you had to come up with a theme that ties all three missions together, it would be "origins." The Titan explorer, for example, will be studying a place that — in a crude way, at least — resembles the early planet Earth at a time when life arose here. Titan, with a thick atmosphere and a bizarro-world form of weather featuring toxic winds and hydrocarbon rain, is home to a mix of complex chemistry, complete with organic molecules. The oceans provide a medium in which the molecules can move around and interact with each other. It's even conceivable, though clearly a long shot, that some form of microscopic life already exists on this frigid moon. The Mars lander, by contrast, would visit a place where the seas — plain water in this case — vanished long ago. But the mission of GEMS goes far deeper than that. By analyzing Marsquakes on the Red Planet, GEMS will try to get a handle on what the interior of Mars is like. Scientists don't currently know whether the planet's core is liquid, like Earth's, or solid, or some mushy consistency in between. It all depends on how efficiently Mars has cooled since it formed 4.5 billion years ago, and that depends in turn on the planet's internal structure. "That's the mission," says Bruce Banerdt, of NASA's Jet Propulsion Laboratory, the lead scientist for GEMS. "We want to understand how Mars was built." Along with sensitive seismographic equipment, GEMS will drill down about 20 ft. (6 m) with a thermometer-equipped probe, trying to figure out how quickly the temperature rises with depth. "That will let us extrapolate all the way down to the center," Banerdt says, "which will tell us how fast Mars is cooling."