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JUPITER, Fla. — Groundbreaking research out of the Scripps Research Institute in Jupiter, Florida found a genetic explanation for the pain processing and sensory issues some children living with autism face."To see the biology in the lab turn out that has parallels to what’s going on in these children takes it so far beyond just an academic endeavor," said Dr. Gavin Rumbaugh, a neuroscientist at Scripps. "You go home every day thinking, unbelievably, I may actually be making a difference in someone's life."One of those children who Rumbaugh hopes to help with his research is 10-year-old Beckett, who lives in Texas."We wanted to understand generally in the lab how genes like SYNGAP1 affect the way the brain functions and we thought what better way was then to look and see how this gene may directly affect sensory processing, and then further on ask the question, 'Does the change in sensory processing actually lead directly to learning, memory and behavioral impairment?' " he said.Beckett has a genetic mutation of SYNGAP1, which researchers have now found causes certain issues he faces, particularly, having an extremely high pain threshold while also experiencing heightened sensitivity to another kind of stimuli. Beckett and other children living with this genetic mutation also often have epilepsy."It's all about quality of life. Everybody deserves to live their best life and that's my mission," said Monica Weldon, Beckett's mom.Weldon said the research being done in Jupiter could change her son's life and the lives of hundreds of other children around the world with the same genetic abnormality and symptoms, some of whom whose families she's connected with online."That is the power I believe of a patient group that is motivated to find treatments for their loved ones," Weldon said. "Also, you've got scientists who are listening. They're willing to listen and they're willing to learn."The next step in Rumbaugh's research is to look at treating the symptoms from the genetic mutation. 2043

re incredibly difficult issues and like the rest of the country, I experienced them actually in a very emotional way."Ivanka Trump met with her father last month to discuss the images of immigrant families being separated at the US-Mexico border, White House spokesman Hogan Gidley told CNN at the time."She offered the President her support and she said she would talk to any member of Congress to help find a legislative solution to the issue," Gidley said.The-CNN-Wire 1812

JAMUL (CNS) - A woman was killed in Jamul late Friday by a hit-and-run driver who officers were ultimately able to track down and arrest, the California Highway Patrol said Saturday.Around 7:20 p.m. Friday, a 65-year-old woman was crossing Route 94 near Rancho Miguel Road when she was struck by a white Toyota Corolla heading west on the highway, CHP officers said.The Corolla driver at first pulled over and got out of the car, then hopped back in and fled the area, continuing west on Route 94, officials said.The victim was taken by ambulance to a hospital, where she succumbed to her injuries, according to the CHP.Neither the driver nor the victim were publicly named.MAP: Track crime happening in your neighborhoodInvestigators were looking for possible witnesses, and asked anyone who saw the crash to call the California Highway Patrol El Cajon office at (619) 401-2000. 887

Kenny Bachman made a responsible decision. After a night of drinking in Morgantown, West Virginia, Bachman opted to use an Uber.Little did Bachman know that rather than returning to his friends' place in Morgantown, Bachman was on a 300-mile journey back to his New Jersey home, according to NJ.com.According to the NJ.com report, Bachman passed out in the passenger seat of a 2011 Honda Odyssey, hours into his costly journey home. When he awakened, instead of just getting out and be stranded in the middle of no where, he decided to keep going."I just woke up," Bachman told NJ.com. "And I'm thinking, 'Why the f--- am I in the car next to some random a** dude I don't even know?"Besides the accidental 300-mile trip, Bachman had to pay extra because he had mistakenly requested an UberXL, and it was surge pricing. Had it not been surge pricing, Bachman would have paid just 9.14, NJ.com reported. Bachman told NJ.com that his driver did not have money to pay for the unexpected tollbooths, so Bachman stopped at a CVS ATM to give the driver cash to use for tolls on the return trip.Although Bachman gave the driver 5 Stars, he protested the charge to Uber, claiming he never put his home address in New Jersey into the app. Uber told NJ.com that the dispute has been resolved, and that Bachman agreed to pay the fare.  1419

Joe Biden was officially nominated as the Democratic nominee for president on Tuesday at the virtual Democratic National Convention. Delegates cast their votes virtually as the in-person convention was canceled due to the coronavirus pandemic. Tuesday's roll call was merely a formality as Biden accumulated more than 50% of pledged delegates during the primaries. Biden is now the nominee-in-waiting, and he will accept the party's nomination on Thursday from Wilmington, Delaware. 490

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