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HONG KONG, July 19 (Xinhua) -- A gene controlled by male hormone was critical for the growth of liver tumor, leading to a higher incidence of the disease in men than in women, according to the Chinese University of Hong Kong which made the results public on Tuesday.There is a significant gender bias in liver cancer incidence. In Hong Kong, men are three times more likely to develop liver cancer than women. Such phenomenon prompted researchers from the university to carry out a genomic location analysis in liver cancer cells starting from 2008.The researchers discovered, out of 17,000 human genes, that a gene called Cell Cycle-Related Kinase (CCRK) was directly controlled by androgen receptor. They further found that CCRK was critical for the induction of signaling pathway leading to abnormal liver cell growth and tumor formation.The results also reveal that 70 percent of patients with liver cancer were found to produce high levels of CCRK. More importantly, these patients were more likely to have late-stage cancers and lived shorter than those with low CCRK level.Using mouse models, the researchers found that either lowering the level or blocking the signaling pathway of CCRK in liver cancer cells could significantly reduce the tumor growth rate.The study has validated that CCRK is an important gene that has potential to cause liver cancer and the gene can be tested as a new targeted therapy in future.Vice-Chancellor of the university Joseph Sung, who is also team leader of the research project, said the results explained why men have a higher risk of liver cancer than women and helped push ahead with the development of a novel treatment of the disease.The above study results were published online in July in Journal of Clinical Investigation.
SAN FRANCISCO, Sept. 22 (Xinhua) -- Former eBay Chief Executive Officer and California governor candidate Meg Whitman on Thursday was named Hewlett-Packard's new CEO, replacing Leo Apotheker who served 11 months on the job."We are fortunate to have someone of Meg Whitman's caliber and experience step up to lead HP," said the California-based company in a statement."We are at a critical moment and we need renewed leadership to successfully implement our strategy and take advantage of the market opportunities ahead," said the troubled tech giant.It noted that the job of the HP CEO now requires additional attributes to successfully execute on the company's strategy, adding Whitman "has the right operational and communication skills and leadership abilities to deliver improved execution and financial performance.""I am honored and excited to lead HP. I believe HP matters -- it matters to Silicon Valley, California, the country and the world," said Whitman in a statement.Whitman, 55, joined the HP board in January and served as president and CEO of eBay from 1998 to 2008, when she led the company through its initial public offering and massive growth.During her last years at eBay, she is blamed for not being able to halt the sales slowdown and overpaying for the 2005 acquisition of Skype with 4.1 billion dollars. In 2009, Skype was sold by eBay at a valuation of 2.75 billion dollars.Whitman won the Republican nomination for governor of California in 2010. She lost the election to Gov. Jerry Brown after spending more than 140 million dollars of her own fortune on the campaign. EnditemHP said the appointments are effective immediately, following the decision that Apotheker stepped down as president and CEO and resigned as a director of the company.Multiple U.S. media reported on Wednesday that Apotheker was to be ousted, sending HP shares soaring on the market and in the after-hour trading.Apotheker, 58, was named HP CEO 11 months ago to replace Mark Hurd, who was ousted due to a scandal over a personal relationship with a company contractor and then became co-president of Oracle. Before HP, Apotheker had served as CEO of German software giant SAP for 10 months.On Aug. 18, Apotheker announced that HP will shut down its mobile business, spin off its core personal computer business and transfer into a cloud-based software and services provider for businesses including a 10.3 billion-dollar acquisition of British software company Autonomy.Shares of the company plunged 20 percent the following day, the worst one-day loss since Black Monday in 1987.On Sept. 30, 2010, the day before Apotheker's appointment as HP CEO, the tech giant's stock closed at 42.04 dollars. On Tuesday, the price closed at 22.47 dollars, a decrease of 46.6 percent in less than a year.On Monday, HP was reported to begin sending over 500 employees pink slips in the WebOS division, after announcing to stop making WebOS devices in August.
CANBERRA, Sept. 23 (Xinhua) -- A genetic study on Friday found Aboriginal Australians are descended from the first people to leave Africa up to 75,000 years ago.Researchers from the University of Western Australia, Murdoch University and an international team analyzed genetic material of a 100-year-old West Australian Aboriginal man's hair, and found he was directly descended from a migration out of Africa into Asia.The study revealed that Australian Aboriginal ancestors split from the first modern human populations to leave Africa, between 64,000 and 75,000 years ago, at least 24,000 years before other human migrations.According to Dr. Joe Dortch, an archaeologist at the University of Western Australia, the discovery rewrites the history of the human species by confirming humans moved out of Africa in waves of migrations rather than in one single out-of-Africa diaspora.It also rewrites the story about how Aborigines arrived in Australia some 50,000 years ago."So far there are no [archaeological] sites that are over 50, 000 years old so it puts a time limit on that and focuses our future efforts," he said in a statement released on Friday.Dr. Dortch believes the finding will foster a sense of pride in modern Australian Aborigines."No-one else in the world can say 'I am descended from people who have been here 75,000 years'."Associate Professor Darren Curnoe, leader of the Human Evolutionary Biology Lab in the School of Biological, Earth & Environmental Sciences at the University of New South Wales, said the study powerfully confirms that Aboriginal Australians are one of the oldest living populations in the world, certainly the oldest outside of Africa."Australians are truly one of the world's great human populations and a very ancient one at that, with deep connections to the Australian continent and broader Asian region. About this now there can be no dispute," he told Xinhua in an email note.Meanwhile, Professor Alan Cooper, Director of the Australian Centre for Ancient DNA (ACAD) at the University of Adelaide, said while this is a major step forward, the key unresolved question remains the unique story of Aboriginal history within Australia, such as what has happened in those 50,000 years of life in the harsh Australian environment."Unfortunately, the information from a single individual tells us very little about this fascinating, and critically important part of human history. Aborigines are one of the oldest continuous human populations outside Africa, as they note in the paper, and due to the geographic isolation and limited archaeological records remain one of the most mysterious chapters in human history," he told Xinhua on Friday.The study is published on Friday in the journal Science.Indigenous Australians are the original inhabitants of the Australian continent and nearby islands. They together make up more than 2.5 percent of Australia's population.
CHENGDU, Sept. 20 (Xinhua) -- A United Nations official said Tuesday that she hopes China will take every opportunity to reinforce, support and lead the UN's agenda and "infuse it with strength and wisdom.""The more China gives, the better the UN can become," said Renata Lok-Dessallien, UN Resident Coordinator and United Nations Development Program (UNDP) Resident Representative in China, at the Seminar in Memory of the 40th Anniversary of the Resumption of Lawful Rights of China in the United Nations.The three-day seminar from Sept. 19 to 21 is being held in the city of Chengdu in southwest China's Sichuan Province. About 100 UN and Chinese officials are gathering to discuss China's role in the UN, as well as the UN's role in global diplomacy.Lok-Dessallien said that the General Assembly Resolution of Oct. 25, 1971 was an "important milestone in China's international relations and in the history of the United Nations.""It restored the rights of the People's Republic of China in the United Nations and marked China's entry to the world stage," she said.Steven Sabey, a senior policy advisor from the UNDP's China office, said that China plays an important role in facilitating cooperation about the member states of the United Nations."China needs the United Nations, and the United Nations also needs China," said Wu Hailong, China's assistant minister of foreign affairs."We must recognize that as the largest developing country in the world, China needs to manage its domestic affairs first, as this can have a positive effect on humanity as a whole," Wu said.As China's role in the world continues to grow and evolve, the UN's role in China will also grow, according to Lok-Dessallien."As China's development trajectory continues to evolve, we are entering significantly new territory in the UN-China relationship," she said.Sabey said that he hopes China will strengthen its cooperation with the United Nations in order to further improve intercultural communication and allow China to contribute more to other developing countries."The United Nations is committed to continuing to deepen and strengthen our partnership as we tackle the many global challenges ahead," said Lok-Dessallien.
WASHINGTON, June 6 (Xinhua) -- Forests in many regions are becoming larger carbon sinks thanks to higher density, U.S. and European researchers say in a new report.In Europe and North America, increased density significantly raised carbon storage despite little or no expansion of forest area, according to the study, led by Aapo Rautiainen of the University of Helsinki, Finland, and published Monday in the on- line, open-access journal PLoS One.Even in the South American nations studied, more density helped maintain regional carbon levels in the face of deforestation.The researchers analyzed information from 68 nations, which together account for 72 percent of the world's forested land and 68 percent of reported carbon mass. They conclude that managing forests for timber growth and density offers a way to increase stored carbon, even with little or no expansion of forest area."In 2004 emissions and removals of carbon dioxide from land use, land-use change and forestry comprised about one fifth of total emissions. Tempering the fifth by slowing or reversing the loss of carbon in forests would be a worthwhile mitigation. The great role of density means that not only conservation of forest area but also managing denser, healthier forests can mitigate carbon emission," says Rautiainen.