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WASHINGTON, June 21 (Xinhua) -- A new study from Harvard School of Public Health (HSPH) and University of California, San Francisco, researchers suggests that men with prostate cancer who smoke increase their risk of prostate cancer recurrence and of dying from the disease. The study will be published Wednesday in the Journal of the American Medical Association."In our study, we found similar results for both prostate cancer recurrence and prostate cancer mortality," said Stacey Kenfield, lead author and a research associate in the HSPH Department of Epidemiology. "These data taken together provide further support that smoking may increase risk of prostate cancer progression."Kenfield and her colleagues conducted a prospective observational study of 5,366 men diagnosed with prostate cancer between 1986 and 2006 in the Health Professionals Follow-Up Study. The researchers documented 1,630 deaths, 524 (32 percent) due to prostate cancer, 416 (26 percent) due to cardiovascular disease, and 878 prostate cancer recurrences.The researchers found that men with prostate cancer who were current smokers had a 61 percent increased risk of dying from prostate cancer, and a 61 percent higher risk of recurrence compared with men who never smoked. Smoking was associated with a more aggressive disease at diagnosis, defined as a higher clinical stage or Gleason grade (a measure of prostate cancer severity). However, among men with non-metastatic disease at diagnosis, current smokers had an 80 percent increased risk of dying from prostate cancer.Compared with current smokers, men with prostate cancer who had quit smoking for 10 or more years, or who had quit for less than 10 years but smoked less than 20 pack-years before diagnosis, had prostate cancer mortality risk similar to men who had never smoked. Men who had quit smoking for less than 10 years and had smoked 20 or more pack-years had risks similar to current smokers."These data are exciting because there are few known ways for a man to reduce his risk of dying from prostate cancer," said senior author Edward Giovannucci, professor of nutrition and epidemiology at HSPH. "For smokers, quitting can impact their risk of dying from prostate cancer. This is another reason to not smoke."Prostate cancer is the most frequently diagnosed form of cancer diagnosed in the United States and the second leading cause of cancer death among U.S. men, affecting one in six men during their lifetime. More than two million men in the U.S. and 16 million men worldwide are prostate cancer survivors.
WASHINGTON, Sept. 14 (Xinhua) -- Controlling diabetes may someday involve mining stem cells from the lining of the uterus, Yale School of Medicine researchers report in a new study published Wednesday in the journal Molecular Therapy. The team treated diabetes in mice by converting cells from the uterine lining into insulin-producing cells.The endometrium or uterine lining, is a source of adult stem cells. These cells generate uterine tissue each month as part of the menstrual cycle. Like other stem cells, however, they can divide to form other kinds of cells.Led by Yale Professor Hugh Taylor, the researchers bathed endometrial stem cells in cultures containing special nutrients and growth factors. Responding to these substances, the endometrial stem cells adopted the characteristics of beta cells in the pancreas that produce insulin. Over the course of a three- week incubation process, the endometrial stem cells took on the shape of beta cells and began to make proteins typically made by beta cells. Some of these cells also produced insulin.After a meal, the body breaks food down into components like the sugar glucose, which then circulates in the blood. In response, beta cells release insulin, which allows the body's cells to take in the circulating glucose. In this study, Taylor and his team exposed the mature stem cells to glucose and found that, like typical beta cells, the cultured cells responded by producing insulin. The team then injected diabetic mice with the mature, insulin-making stem cells. The mice had few working beta cells and very high levels of blood glucose.Mice that did not receive the stem cell therapy continued having high blood sugar levels, developed cataracts and were lethargic. In contrast, mice that received the cell therapy were active and did not develop cataracts, but the animals' blood sugar levels remained higher than normal.The Yale team's findings suggest that endometrial stem cells could be used to develop insulin-producing islet cells, which are found in the pancreas. These islet cells could then be used to advance the study of islet cell transplantation to treat people with diabetes.Taylor said in a statement that the next step in the research will be to verify how long this treatment remains effective.
CANBERRA, Aug. 31 (Xinhua) -- Australia's new chief medical officer, Professor Chris Baggoley, on Wednesday said Australian should not be worried about reports that a mutant strain of the deadly bird flu virus is spreading across Asia and beyond.On Monday, the UN's Food and Agriculture Organization (FAO) said a mutant strain of the deadly avian influenza virus was spreading in Asia and issued a warning that the bird flu could spread from poultry to humans. It urged "heightened readiness and surveillance" as the mutant strain posed "unpredictable risks to human health."But Professor Baggoley, who took office on Tuesday, said Australia is well served by strict testing and customs regimes, adding that avian migration patterns also mean infected birds are highly unlikely to arrive in Australia."I don't think we should be worried," Prof Baggoley told Sky News."The country and the Australian government is certainly vigilant in relation to bird flu."Prof. Baggoley insisted the H5N1 virus remains overwhelmingly a disease of birds and it is very uncommon for humans to catch it. It is also exceedingly rare for humans to spread it among themselves.He said that even if bird flu did arrive and affected humans, Australia is ready to respond to any new and significant developments in bird flu."Australia tests migratory wild birds, looking for H5N1, and has been doing this for some years and has never found it," he said."On the human side of things, Australia has been preparing for a possible outbreak of H5N1 since 2004."We've got the laboratory capacity to diagnose influenza; we've got arrangements in place for a rapid production of an H5N1 vaccine for humans, and we've got ready access to antivirals."There have been no outbreaks of bird flu in Australia to date.The UN said the latest human death from bird flu occurred earlier this month in Cambodia, which has registered eight cases of human infection this year, all of them fatal.H5N1 has infected 565 people since it first appeared in 2003, killing 331.
LOS ANGELES, July 7 (Xinhua) -- Obesity rates in the United States climbed over the past year in 16 states, and not a single state reported a decline in the proportion of excessively overweight residents, according to a report released on Thursday.The report, published by HealthDay News, found that more than 30 percent of the people in 12 states are obese. Four years ago, only one state could make that claim.Twenty years ago, "there wasn't a single state that had an obesity rate above 15 percent, and now every state is above that," said Jeff Levi, executive director of Trust for America's Health, which compiled the report."We have seen a dramatic shift over a generation," he added. " This isn't just about how much people weigh, but it has to do with serious health problems like diabetes and hypertension. These are the things that are driving health care costs."With the exception of Michigan, the 10 most obese states are in the South. The Northeast and West reported the lowest obesity rates. In addition, in eight states, more than 10 percent of adults suffer from type 2 diabetes, according to the report.Mississippi, where 34.4 percent of the people are obese, has the highest obesity rate. Other states with obesity rates above 30 percent include: Alabama, Arkansas, Kentucky, Louisiana, Michigan, Missouri, Oklahoma, South Carolina, Tennessee, Texas and West Virginia. Thirty-eight other states have obesity rates above 25 percent.For the second year in a row, obesity rates rose in Illinois, Kentucky, Massachusetts, Missouri, Rhode Island and Texas.And, for the third year straight, more residents of Florida, Kansas, Maine, Oklahoma and Vermont tipped the scale toward obesity.Colorado, with an obesity rate of 19.8 percent, is the only state where the rate is less than 20 percent, the report found.The study also found that more than one-third of children and adolescents are obese or overweight, with the highest prevalence in the South. However, the new data indicate that obesity among children and adolescents may have leveled off, except among the heaviest boys.
BEIJING, Aug. 13 (Xinhua) -- The quality of the products China exported to the European Union (EU) improved during the first half of this year due to strict quality control measures, according to quality control authorities.The number of quality complaints made by the EU regarding Chinese imports declined by 45 percent in the first half of 2011, according to the General Administration of Quality Supervision, Inspection and Quarantine (AQSIQ).The administration attributed the improved quality to its nationwide crackdown on counterfeited and substandard products.The administration launched a nationwide quality checkup in the first half of this year. Of the 4,815 batches of products that the quality control authorities checked between January and June, just 9.4 percent failed quality tests, 1.7 percentage points lower than that of the same period of last year, according to the administration.A total of 218,000 counterfeiting cases have been investigated so far this year, involving goods worth a total of 9.5 billion yuan (1.49 billion U.S. dollars), the administration said.