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SAN DIEGO (KGTV) — It's Halloween week in San Diego, which means ghouls and goblins will be out to celebrate.Thursday, San Diego Zombie Crawl and and Pillage the Village hit town, giving trick-or-treaters of all ages the chance to celebrate the holiday.Día de los Muertos events also kick off this weekend, with celebrations for families to honor their families and friends in Old Town, Oceanside, Escondido, and elsewhere.Outside of the seasonal festivities, San Diego Beer Week kicks off at several breweries around the county with beer releases and specials, food pairings, and more. And the Carlsbad Village Faire promises to provide families with plenty to explore in Carlsbad, and the Fall Back Festival takes visitors back in time in the Gaslamp District.Here's a look at events to check out this weekend in San Diego:THURSDAYSan Diego Zombie Crawl Where: Gaslamp District; Cost: and upOne ticket to the San Diego Zombie Crawl grants guests access to five days of fun at more than 20 parties throughout the Gaslamp District. Day 1-3 celebrate the Halloween season with some wicked parties downtown, while the second weekend will celebrate Dia de los Muertos. Guests get the welcome shots, access to the crawl's finale party, exclusive food and drink specials.Pillage the Village and Dog-O-WeenWhere: La Jolla; Cost: FreeTake the kids out trick-or-treating in La Jolla village and frolic with all the superheroes, ghosts, and princesses during Pillage the Village. Visit merchants for a special Halloween treat and bring your pooch for a Dog-O-Ween celebration as well.FRIDAYDía de los Muertos events in San DiegoWhere: Various locations; Cost: Varies(Friday - Saturday) San Diego will hosting several Día de los Muertos events around the county this weekend. Check out celebrations that honor friends and family in Old Town, Escondido, Oceanside, and Coronado. San Diego Beer WeekWhere: Various locations; Cost: Varies(Friday - Sunday) San Diego's 10-day celebration of beer returns as San Diego Beer Week brings more than a week of special beer releases, beer gardens, drink specials, food pairings, and much more to local breweries.SATURDAYEscondido Tamale FestivalWhere: Grape Day Park; Cost: FreeEnjoy all the tamales you can handle at this celebration of the delicious dish in Escondido. Attendees will enjoy tamales from tons of food vendors, craft beers, tamale contests, a car show, live entertainment, arts and crafts, and more.Bike the CoastWhere: Oceanside; Cost: - 0Go for a ride through North County and take in pristine views of San Diego's coastal communities during Bike the Coast. The route takes riders along a 25-mile, 50-mile, or 100-mile course to a finish line festival at Oceanside Pier with music and food.Ramona Art and Wine FestWhere: Begent Ranch; Cost: - Sip on fine wines and enjoy artisan cuisine in Ramona during the Art and Wine Festival. Local artists will showcase their works and hand-painted wine barrels will be auctioned off to benefit the Ramona H.E.A.R.T. Mural Project.SUNDAYRace for the CureWhere: Balboa Park; Cost: - Lace up and help fund research and awareness for breast cancer and breast cancer survivors during the annual Susan G. Komen Race for the Cure. Runners get a special race t-shirt and can enjoy opening an closing ceremonies honoring survivors and those who we've lost to the disease.Carlsbad Fall Village FaireWhere: Carlsbad Village; Cost: FreeCheck out decor, arts and crafts, and unique gifts from more than 750 vendors during Carlsbad's massive village fair. Kids can enjoy carnival rides and games, and families will enjoy live music, delicious international foods, and a beer and wine garden.Fall Back FestivalWhere: Gaslamp District; Cost: FreeIt's time to fall back and the Gaslamp District is celebrating with a street fair featuring historical activities from way back. Kids can pan for gold, observe blacksmiths displaying their trade, or saddle up for a pony ride in the heart of San Diego. 4001

SAN DIEGO (KGTV) - Mariah Sunshine Coogan's family says she lived up to her middle name. "She would walk into a room, and she would just light it up," her mother, Stacey Coogan, told 10News. The 23-year-old died Monday night when a plane carrying her and six others crashed in Scottsdale, Arizona. The Piper PA24 plane crashed at around 8:45 p.m. local time, shortly after it took off from the Scottsdale Airport.RELATED:  445

SAN DIEGO (KGTV) — In the race for a coronavirus vaccine, scientists often say we need more than one winner.That’s in part because different vaccines use different strategies to provoke the immune system, and each strategy has different strengths.Take the inactivated virus vaccine, an approach currently used in the vaccine against the poliovirus. In this approach, scientists take a live virus, kill it with chemicals or heat, and then introduce that viral corpse into a person.There are three groups in the final phase of human trials using inactivated coronavirus, primarily in China, according to a tracker from the Milken Institute.“The immune system can tell the difference between something that's a real threat and something that's not a threat, and so if you get injected with a dead virus your immune system has the tendency to not pay a lot of attention to that,” said Dr. Shane Crotty of the La Jolla Institute for Immunology.The downside of the inactivated virus approach is that it only elicits two out of the three of the parts of the immune system, Dr. Crotty said. It’s capable of producing antibodies and helper T-cells, but not killer T-cells.The modern take on the inactivated virus approach is called a viral vector vaccine.In this strategy, scientists combine elements of the coronavirus with a common cold virus called an adenovirus that won’t make you sick. Since the virus is alive, it can elicit all three kinds of immune responses, Dr. Crotty said.“There are no licensed vaccines right now that use that strategy, but there are all kinds of vaccine trials that have been done around the world with those types [of vaccines] showing that they're straightforward to manufacture. They're very safe,” he said.The University of Oxford is testing a viral vector vaccine for COVID-19 in a Phase 3 clinical trial.Then there are subunit vaccines. These include just a section -- or subunit -- of the virus’ protein.UC San Diego is working on a coronavirus candidate vaccine using this approach.There are subunit vaccines currently on the market for tetanus and other viruses.“Working with proteins is more challenging, just from a laboratory and manufacturing perspective,” Dr. Crotty said.Enter the next phase of vaccine development. Instead of using the virus itself or fragments of it, Inovio Pharmaceuticals is working on a vaccine strategy using just the virus’ genetic information.DNA-based vaccines simply introduce a genetically engineered blueprint of the virus into a person, and the cells do the rest.“Some people get confused about this. They think it’s a genetic vaccine that changes their DNA and becomes part of them, and that’s definitely not the case.” Dr. Crotty said. “They don’t become part of you. Your body chews them up.”Researchers have been working on DNA-based vaccines for about 20 years, Crotty said, but none are currently licensed for use.San Diego-based Arcturus Therapeutics is using an RNA-based approach, along with other companies like Pfizer and Moderna that have entered Phase 3 trials.Messenger RNA reads the DNA instructions and helps translate them into proteins.Dr. Crotty said the DNA and RNA approaches have similar drawbacks and benefits: they’ve never been approved for us, but both can be developed rapidly because they don’t require access to the physical virus.Around the world, there are more than 200 coronavirus vaccines currently in development, according to the Milken Institute. 3459

SAN DIEGO (KGTV) - It’s more affordable to rent than buy a home in San Diego, according to a report released Thursday. The 2020 Rental Affordability Report consisting of census data compiled by ATTOM Data Solutions broke down the figures for counties nationwide. Although the price of owning a median-priced three-bedroom home was more affordable than renting in 53 percent of U.S. counties studied, renting was a better financial decision in highly populated suburban or urban areas. RELATED: San Diego expected to be California's hottest housing market in 2020, despite coolingIn counties with a population of more than one million people, including San Diego, renting was a more affordable option 84 percent of the time. Los Angeles County and the counties of Phoenix, Las Vegas, San Francisco, and Seattle were also included in the figure. San Diego made the list of major counties where rents consume the highest percentage of average wages. 1. Santa Cruz County: 82.1 percent2. Marin County: 75.3 percent3. Park County, CO (Denver): 74.3 percent4. Honolulu County, HI: 74.2 percent5. Kauai County, HI: 73.7 percent6. Kings County, NY (Brooklyn): 65.3 percent7. Orange County: 64.7 percent8. San Diego County: 59.6 percent9. Contra Costa County: 58.4 percent10. Queens County, NY: 57.4 percentSan Diego was also one of the counties where home prices rose faster than wages and wage growth outpaced rent growth. RELATED: Making It in San Diego: City may weigh 'vacancy tax' targeting empty homesRegions where buying is the best idea included Miami, Tampa, Detroit, Cleveland, and Pittsburgh. </noscript><object class="tableauViz" style="display:none;"> </noscript> “Home ownership is a better deal than renting for the average wage earner in a slim majority of U.S. housing markets. However, there are distinct differences between different places, depending on the size and location from core metro areas,” said Todd Teta, chief product officer with ATTOM Data Solutions. “For sure, either buying or renting is a financial stretch or out of reach for individual wage earners throughout most of the country in the current climate. But with interest rates falling, owning a home can still be the more affordable option, even as prices keep rising.” RELATED: Making it in San Diego: Key saving steps helped renter buy her first homeThe report included 2019 and 2020 data from the U.S. Department of Housing and Urban Development, Bureau of Labor Statistics, and public record sales data from ATTOM Data Solutions. Read the full study here. 2585

SAN DIEGO (KGTV) - It’s more affordable to rent than buy a home in San Diego, according to a report released Thursday. The 2020 Rental Affordability Report consisting of census data compiled by ATTOM Data Solutions broke down the figures for counties nationwide. Although the price of owning a median-priced three-bedroom home was more affordable than renting in 53 percent of U.S. counties studied, renting was a better financial decision in highly populated suburban or urban areas. RELATED: San Diego expected to be California's hottest housing market in 2020, despite coolingIn counties with a population of more than one million people, including San Diego, renting was a more affordable option 84 percent of the time. Los Angeles County and the counties of Phoenix, Las Vegas, San Francisco, and Seattle were also included in the figure. San Diego made the list of major counties where rents consume the highest percentage of average wages. 1. Santa Cruz County: 82.1 percent2. Marin County: 75.3 percent3. Park County, CO (Denver): 74.3 percent4. Honolulu County, HI: 74.2 percent5. Kauai County, HI: 73.7 percent6. Kings County, NY (Brooklyn): 65.3 percent7. Orange County: 64.7 percent8. San Diego County: 59.6 percent9. Contra Costa County: 58.4 percent10. Queens County, NY: 57.4 percentSan Diego was also one of the counties where home prices rose faster than wages and wage growth outpaced rent growth. RELATED: Making It in San Diego: City may weigh 'vacancy tax' targeting empty homesRegions where buying is the best idea included Miami, Tampa, Detroit, Cleveland, and Pittsburgh. </noscript><object class="tableauViz" style="display:none;"> </noscript> “Home ownership is a better deal than renting for the average wage earner in a slim majority of U.S. housing markets. However, there are distinct differences between different places, depending on the size and location from core metro areas,” said Todd Teta, chief product officer with ATTOM Data Solutions. “For sure, either buying or renting is a financial stretch or out of reach for individual wage earners throughout most of the country in the current climate. But with interest rates falling, owning a home can still be the more affordable option, even as prices keep rising.” RELATED: Making it in San Diego: Key saving steps helped renter buy her first homeThe report included 2019 and 2020 data from the U.S. Department of Housing and Urban Development, Bureau of Labor Statistics, and public record sales data from ATTOM Data Solutions. Read the full study here. 2585