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The first participant in a clinical trial for a vaccine to protect against the new coronavirus will receive an experimental dose on Monday, according to a government official.The National Institutes of Health is funding the trial, which is taking place at the Kaiser Permanente Washington Health Research Institute in Seattle. The official who disclosed plans for the first participant spoke on condition of anonymity because the move has not been publicly announced.Public health officials say it will take a year to 18 months to fully validate any potential vaccine. Testing will begin with 45 young, healthy volunteers with different doses of shots co-developed by NIH and Moderna Inc. There’s no chance participants could get infected from the shots, because they don’t contain the virus itself. The goal is purely to check that the vaccines show no worrisome side effects, setting the stage for larger tests.Dozens of research groups around the world are racing to create a vaccine as COVID-19 cases continue to grow. Importantly, they’re pursuing different types of vaccines — shots developed from new technologies that not only are faster to produce than traditional inoculations but might prove more potent. Some researchers even aim for temporary vaccines, such as shots that might guard people’s health a month or two at a time while longer-lasting protection is developed.Also in the works: Inovio Pharmaceuticals aims to begin safety tests of its vaccine candidate next month in a few dozen volunteers at the University of Pennsylvania and a testing center in Kansas City, Missouri, followed by a similar study in China and South Korea.Even if initial safety tests go well, “you’re talking about a year to a year and a half” before any vaccine could be ready for widespread use, according to Dr. Anthony Fauci, director of NIH’s National Institute of Allergy and Infectious Diseases.That still would be a record-setting pace. But manufacturers know the wait — required because it takes additional studies of thousands of people to tell if a vaccine truly protects and does no harm — is hard for a frightened public.President Donald Trump has been pushing for swift action on a vaccine, saying in recent days that the work is “moving along very quickly” and he hopes to see a vaccine “relatively soon.”Today, there are no proven treatments. In China, scientists have been testing a combination of HIV drugs against the new coronavirus, as well as an experimental drug named remdesivir that was in development to fight Ebola. In the U.S., the University of Nebraska Medical Center also began testing remdesivir in some Americans who were found to have COVID-19 after being evacuated from a cruise ship in Japan.For most people, the new coronavirus causes only mild or moderate symptoms, such as fever and cough. For some, especially older adults and people with existing health problems, it can cause more severe illness, including pneumonia. The worldwide outbreak has sickened more than 156,000 people and left more than 5,800 dead. The death toll in the United States is more than 50, while infections neared 3,000 across 49 states and the District of Columbia. The vast majority of people recover. According to the World Health Organization, people with mild illness recover in about two weeks, while those with more severe illness may take three weeks to six weeks to recover.___The Associated Press receives support for health and science coverage from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 3597

The Hurricane Center said there is a 100% chance of a tropical depression forming in the Gulf of Mexico. They say by Thursday night it's forecast to become a tropical storm and by Friday it could form into a hurricane.Tropical storm and storm surge watches have been issued for parts of Louisiana.The governor of Louisiana declared a state of emergency on Wednesday ahead of the storm. 397

The National Retail Federation does surveys on this every year and time and time again, gift cards are the most requested holiday gift. But every single year, 171

The keyboard has replaced the pen these days, and it is truly just as mighty. The owners of DJ’s Bar and Grill on the bypass in Winchester, Kentucky, can attest to that. “It’s alarming to think that this is the caliber of the general public, or the intelligence level we’re dealing with day to day,” said Danielle Ratliff. Three Decembers ago, a post appeared on Facebook about a restaurant refusing to serve ten of the 35 meals it had prepared for a group of veterans. The 25 who were there, wanted to serve the extra meals to homeless vets.The restaurant, which also goes by the name DJ’s, apparently refused. Since it’s an anniversary month for that post, it was re-shared and from coast to coast people got wind of it. Many, however, decided to not read all of it. They missed the fact that the post was from 2016. Missed the fact that it was directed at DJ’s of Pueblo, Colorado. “Armed” with that lack of knowledge, they decided to come after Gary Rison’s establishment in Clark County.“Even this morning, I responded to more negativity,” Rison said. He referred to an old restaurateur adage about how one negative review can reach 100 people, but one nice review might reach only five people. This had the same kind of impact. Comments to DJ’s (the one in Winchester, not Pueblo) Facebook page came from as far away Arkansas, and Nebraska. People there claiming DJ’s actions on that night to be “shameful,” and “disgraceful.” Rison and his daughter have responded to most of the comments, and many people deleted their negative posts once they had, you know, the facts. This story could’ve been as juicy as the steaks at DJ’s (Winchester, not Pueblo), if it had been even remotely accurate. 1709

The Bellagio hotel-casino on the Las Vegas Strip has unveiled a new, limited-run fountain show based on "Game of Thrones." It's a spectacle that has everyone talking not only in Las Vegas, but around the world. The megahit HBO series has taken TV by storm, getting viewers hooked on a medieval fantasy world.The final season of "Game of Thrones" premiers on April 14, and the quest for the throne begins at the Fountains of Bellagio.The new show didn't disappoint crowds who watched brand-new special effects and listened to a special score."I got goose bumps when I saw this. It was just epic to see it played out here at the Bellagio," said Ramin Djawadi, score composer for the series "Game of Thrones.""It was unbelievable to experience it," Djawadi said.This fountain show, which lasts only two weeks, is like no other in the attraction's 20-year history of dazzling crowds on the famed Las Vegas Strip."It was definitely different. There were so many different things going into it: the projection, the fire," said Peter Kopik, director of choreography and design for WET Design, the company behind the Fountains of Bellagio."For the two people out there who don't know what 'Game of Thrones' is," WET CEO Mark Fuller joked with Action News, "it is the absolutely ultimate experience in theater and storytelling."Crowds lining the Strip before the Sunday night premiere gave the show rave reviews."The fire was awesome. You could feel the flames," said Corey Olcsvary. "The lighting effects, seeing the dragon coming through, the fire and the ice kind of battling against each other, it makes me watch to catch up with the seasons," the Seattle resident told Action News.The show will take place nightly at 8 and 9:30 p.m. ending on April 13.WATCH FULL SHOW BELOW 1781