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BERLIN, June 1 (Xinhua) -- Germany's disease control center reported on Wednesday 365 new cases of the fatal enterohemorrhagic E. coli (EHEC), which marked a sharp rise since its outbreak in the middle of May.Twenty-five percent of the new cases involved the hemolytic- uremic syndrome (HUS), a serious complication resulting from E. coli infection that affects the blood and kidneys, Germany's Robert Koch Institute said.Until now 17 people in Europe, one in Sweden, the other in Germany have been killed by the deadly disease, while the source of the infection was still not identified.According to the data of Robert Koch Institute, at present 470 patients are suffering from HUS due to the infection, raising concerns that the death toll could be even higher in the future.Germany's Agriculture and Consumer Protection Minister Ilse Aigner defended Germany's previous alert on cucumbers from Spain on Wednesday."The fatal strain of EHEC bacteria was indeed found on Spanish cucumbers. According to the European rules, a quick warning must be sent out," she told a local TV station.Laboratory tests in Hamburg on Tuesday overthrew the previous finding that Spanish cucumbers were the sources of the outbreak.As a result of the alert, Europe and Russia imposed bans on Spanish vegetables, leaving Spanish farmers a loss of 200 million euros (287.5 million U.S. dollars) a week.Spain has expressed its intention to take possible legal actions against authorities in Hamburg and ask for compensations from Germany and the European Union.

WASHINGTON, Aug. 17 (Xinhua) -- Latest research shows that the Moon could be younger than previous estimates. The findings were published online Wednesday in the Nature journal.The prevailing theory of the Moon's origin is that it was created by a giant impact between a large planet-like object and the proto-Earth. The energy of this impact was sufficiently high that the Moon formed from melted material that was ejected into space. As the Moon cooled, this magma solidified into different mineral components. Analysis of lunar rock samples thought to have been derived from the original magma has given scientists a new estimate of the Moon's age.According to this theory for lunar formation, a rock type called ferroan anorthosite, or FAN, is the oldest of the Moon's crustal rocks, but scientists have had difficulty dating FAN samples. The research team used newly refined techniques to determine the age of a sample of FAN from the lunar rock that was brought back to Earth by the Apollo 16 mission in 1972.The team analyzed the isotopes of the elements lead and neodymium to place the FAN sample's age at 4.36 billion years. This figure is significantly younger than earlier estimates of the Moon's age that range as old as the age of the solar system at 4. 568 billion years. The new, younger age obtained for the oldest lunar crust is similar to ages obtained for the oldest terrestrial minerals -- zircons from western Australia -- suggesting that the oldest crusts on both Earth and Moon formed at approximately the same time, and that this time dates from shortly after the giant impact.This study is the first in which a single sample of FAN yielded consistent ages from multiple isotope dating techniques. This result strongly suggests that these ages pinpoint the time at which the sample crystallized."The extraordinarily young age of this lunar sample either means that the Moon solidified significantly later than previous estimates, or that we need to change our entire understanding of the Moon's geochemical history," Carnegie Institute of Science's geochemist and study author Richard Carlson said.

CANBERRA, Sept. 7 (Xinhua) -- A team of Australian and U.S. scientists on Wednesday said they discovered a genetic defect, which can lead to Leigh syndrome, a rare disorder which affects the central nervous syndrome.The scientists tested more than 1000 genes by encoding proteins active in two individuals who suffer from the illness. They used a new technique known as next-generation DNA sequencing to examine the genes.The gene they discovered encodes an enzyme which is found in the mitochondria which are subsets of cells. Without this enzyme the mitochondria do not translate proteins efficiently, and this then causes Leigh syndrome.According to David Thorburn, from the Murdoch Children's Research Institute in Melbourne, the discovery shows the enormous potential of the new technology."These findings demonstrate the ability of sequencing technologies to improve diagnosis," Professor Thorburn said in a statement released on Wednesday."Although it isn't clear in the case of Leigh syndrome whether the precise molecular diagnosis will necessarily lead to therapies, the current findings represent a meaningful service."He added that diagnosis of the disease along with its specific genetic cause can also be informative about the risk a couple has of having another affected child. The diagnostic information can help in decisions about whether and how to pursue alternative means of having children, for instance through the use of donor sperm or eggs.The research team consisted of scientists from Australia's Murdoch Institute as well as the Broad Institute in the U.S.In Leigh syndrome, infants are born apparently healthy only to develop movement and breathing disorders that worsen over time, often leading to death by the age of three. The problem is that the mitochondria responsible for powering their cells cannot keep up with the demand for energy in their developing brains.

WASHINGTON, Sept. 12 (Xinhua) -- An enzyme that appears to play a role in controlling the brain's response to nicotine and alcohol in mice might be a promising target for a drug that simultaneously would treat nicotine addiction and alcohol abuse in people, U.S. researchers find.Over the course of four weeks, mice genetically engineered to lack the gene for protein kinase C (PKC) epsilon consumed less of a nicotine-containing water solution than normal mice, and were less likely to return to a chamber in which they had been given nicotine. In contrast, normal mice steadily increased their consumption of nicotine solution while the mice lacking PKC epsilon did not.The study conducted by researchers at the Ernest Gallo Clinic and Research Center, affiliated with the University of California, San Francisco, appeared Monday in the online edition of the Proceedings of the National Academy of Sciences.In normal mice, as in humans, nicotine binds to a certain class of nicotinic receptors located on dopamine neurons, which causes dopamine to be released in the brain. Dopamine creates a feeling of enjoyment, and thus prompts a sense of reward. Researchers found that mice lacking PKC epsilon are deficient in these nicotinic receptors.The finding complements earlier research in which researchers found that mice genetically engineered to lack the PKC epsilon enzyme drank less alcohol than normal mice and were disinclined to return to a chamber in which they had been given alcohol."This could mean that these mice might not get the same sense of reward from nicotine or alcohol," said Gallo senior associate director and investigator Robert Messing. "The enzyme looks like it regulates the part of the reward system that involves these nicotinic receptors."The reward system is a complex of areas in the brain that affect craving for nicotine, alcohol and other addictive substances.The next step in the research, said Messing, would be to develop compounds that inhibit PKC epsilon. The ultimate goal, he added, would be medications that could be used "to take the edge off of addiction by helping people get over some of their reward craving."

SAN FRANCISCO, Sept. 6 (Xinhua)-- Yahoo on Tuesday fired Chief Executive Officer Carol Bartz and replaced her temporarily with the company's chief financial officer."On behalf of the entire board, I want to thank Carol for her service to Yahoo during a critical time of transition in the company's history, and against a very challenging macro-economic backdrop," said Yahoo Chairman Roy Bostock in a news release.The Yahoo Board of Directors appointed CFO Timothy Morse as interim CEO who will manage the company's day-to-day operations until a permanent chief executive is chosen.Carol Bartz, chief executive of Internet company Yahoo Inc, is shown in this undated publicity photo released to Reuters January 13, 2009. Before Yahoo's formal announcement, several news organizations and tech blogs posted an email reportedly from Bartz sent from her iPad to all employees of the company."To all, I am very sad to tell you that I've just been fired over the phone by Yahoo's Chairman of the Board. It has been my pleasure to work with all of you and I wish you only the best going forward."Bartz, 63, took over the Yahoo CEO role from co-founder Jerry Young in January 2009, when the company was struggling to stay competitive and profitable in a market dominated by Google. However, Yahoo never reached the heights she had foreseen.In the most recent quarterly earnings report in June, Yahoo reported net revenue of 1.1 billion U.S. dollars, down 5 percent from last year.Morse, 42, was hired as executive vice president and CFO at Yahoo in July 2009. "It is an honor to be selected for this role," he said in a statement Tuesday.Yahoo said it is starting a search for a new permanent CEO and plans to hire a "nationally recognized executive search firm" to assist in the effort.

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