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GENEVA — The U.N. health agency says the world’s largest randomized trial of COVID-19 treatments found “conclusive evidence” that remdesivir, a drug used to treat U.S. President Donald Trump when he fell ill, has little or no effect on severe cases. The World Health Organization has announced long-awaited results of its six-month “Solidarity Therapeutics Trial” that endeavored to see if existing drugs might have an effect on the coronavirus. The study, which was not peer-reviewed, found that four treatments tested — remdesivir, hydroxychloroquine, lopinavir/ritonavir and interferon — had “ little or no effect on 28-day mortality or the in-hospital course of COVID-19 among hospitalized patients.” Remdesivir was the only drug of the four that had not largely been ruled out as ineffective in fighting COVID-19. 826

Have you ever wanted to own a Jelly Belly factory? Well, the man behind the Jelly Belly name, David Klein, is offering people the chance to do just that.According to a press release, Klein is getting ready to retire and wants to allow someone to win thousands of dollars, plus their very own candy factory.Klein and his partner have hidden "gold-style tickets in the form of necklaces" across the nation to host treasure hunts in each state.To join the search, or to receive valuable clues, you must purchase a .99 ticket for each state."The biggest and best part of these treasure hunts is that anyone who joins at least one treasure hunt will be eligible to search for THE ULTIMATE TREASURE, which will be the key to one of his candy factories and an all-expenses-paid trip and education to a candy-making university," Klein said.Klein said that each treasure hunt is valued at ,000, and only 1,000 people can participate in each treasure hunt.The Jelly Belly Candy Company released the following statement to clear up any misconceptions about the contest Klein is hosting: 1088

Hoover police can't seem to get their story straight on why an officer killed a man at an Alabama mall.First, they said a 21-year-old suspect shot and wounded two other people. Then they said?Emantic Bradford didn't pull the trigger, but brandished a gun. Now we've learned Bradford didn't necessarily do that, either.All the while, the real assailant who opened fire at the mall is still on the loose.Here's a quick breakdown of shifting police narrative: 469

GRAND RAPIDS, Mich. — As we get closer to a potential COVID-19 vaccine approval in the U.S., doctors are hoping the public actually gets the vaccine once it’s available.Recent polling from Pew Research shows about 60% of Americans say they would ‘definitely’ or ‘probably’ get a COVID-19 vaccine.Local infectious disease doctors tell WXMI that that number will be just enough to put a serious dent in infections, but the more immunity, the better.Dr. Andrew Jameson, the Division Chief for Infectious Disease at Mercy Health said, “I am optimistic for the first time in a while.”Dr. Jameson added that he’s seeing a bit of light at the end of a very long tunnel with a COVID vaccine approval potentially just days away.“I can tell you right now from what I’ve seen, from an efficacy standpoint, from a safety standpoint, I am going to be definitely getting the vaccine personally and I have zero issues of giving my family the vaccine when it’s available,” Dr. Jameson said.With two COVID-19 vaccines on deck for approval with the FDA, one from Pfizer and one from Moderna, Dr. Jameson is hoping that people feel confident in getting it once they’re able.“If we get about 60% of people immunized and then we also have the natural immunity out there giving us a little bit of extra help, I think that is going to be a huge impact,” Dr. Jameson said.Dr. Jameson said he also understands that people may be wary of such a new vaccine.“Unfortunately, we’ve had a fair amount of skepticism in the community about vaccines before all of this, and now in the setting of this being moved forward pretty quickly, I think there’s probably a little bit of a natural skepticism,” he said.He said the biggest reason he’s heard for not wanting the vaccine is that things are just moving too fast.“Before this, the fastest that we ever had a vaccine get from the beginning to the end to where people were getting it, was four years, and this one is going to be about 10 months,” Dr. Jameson said.Dr. Jameson called the trial and manufacturing process of both companies vaccines, ‘the most transparent’ he’s ever seen and trusts the FDA to leave no stone unturned before approval.“They get all the notes from the doctors, they get all the patient encounter visits from the sites that are doing the vaccine, so they actually get all of the raw data and re-interpret it and re-analyze it themselves for efficacy, so they don’t just believe what the drug manufacturers tell them,” he explained.He wants people to also understand potential vaccine side effects, to make sure they come back for their second dose. Both Moderna and Pfizer vaccines require two doses given several weeks apart to reach full effectiveness.“If I know that my arm is going to hurt, and I might have a headache, and I might feel run-down for a day or two, if I know that, it’s very different than if that’s a surprise to me,” he said.The FDA is scheduled to meet on Thursday to review the Pfizer vaccine and then again on Dec. 17 to look over Moderna’s vaccine.This story was first reported by Annie Szatkowski at WXMI in Grand Rapids, Michigan. 3109

Home gardeners with some extra time during the coronavirus pandemic might consider adding a personal touch to their yards. An ordinary landscape can be transformed with some imagination, design, and perhaps the help of a local agriculture extension service, landscape professional or private nursery. Adding arbors or pergolas can entice visitors into the garden. Flowering trees, pots, paths and landscape timber might keep them there longer. Experts say benches and tables are a must for an outdoor hangout, and having limited room shouldn’t be a deterrent. Adding the right flowering plants can convince hummingbirds and butterflies to stay longer. 659