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LOS ANGELES, July 18 (Xinhua) -- At least 70 genetic mutations may be involved in the formation of colon cancer, far more than scientists previously thought, a new study suggests.The study by researchers at University of Texas (UT) Southwestern Medical Center contradicts previous thinking that only a few mutated genes may play a role in the development of colon cancer."The ways we've been treating patients up to now is to just go after one target when we should be going after three to four different pathways simultaneously," said Dr. Jerry W. Shay, vice chairman and professor of cell biology at UT Southwestern.The new study identified 65 candidate genes and at least five passenger genes whose mutations play significant roles in cancer development. Inactivating the function of any of these tumor- suppressing genes led to a key step in cancer development called anchorage-independent growth, meaning cells piled up on top of each other rather than aligning neatly.According to previous studies, there were 151 candidate genes and that mutations in just eight to 15 of them would lead to cancer. There were 700 other genes classified as passenger genes whose mutations were incidental to cancer growth.Current cancer treatments target just one or two known cancer- driver genes. While patients may get transient tumor burden reduction, almost universally tumor growth returns."Those numbers are dead wrong," Dr. Shay said, suggesting a new approach to colon cancer treatments targeting multiple genes and pathways simultaneously.The next step is further research to classify more accurately which genes drive cancer and which are merely passengers, the researchers said.Study findings were published in the July 2011 Cancer Research (Priority Reports).

WASHINGTON, Sept. 27 (Xinhua) -- At least 13 people had been killed amid 72 sickened in 18 states in listeria outbreak traced to Colorado cantaloupes, making it the most deadly U.S. outbreak of food-borne infection since 1998, the Centers for Disease Control and Prevention (CDC) said Tuesday in a statement posted on its website.Of the 13 deaths, four were in New Mexico, two were in Colorado, two were in Texas, and there was one each in Kansas, Maryland, Missouri, Nebraska and Oklahoma.Victims range in age from 35 to 96 years, with an average age of 78. All of the illnesses started on or after July 31.The figures were the latest confirmed as of Monday morning, according to the CDC. But they may well rise in the still-widening outbreak as state and local officials are investigating three additional deaths that may be connected.In 1998, 21 people died from listeria linked to tainted hot dogs, according to a CDC online database.The Food and Drug Administration on Sept. 14 warned consumers not to eat cantaloupes from Colorado's Rocky Ford region shipped by Jensen Farms. The cantaloupes with the brand name Rocky Ford were distributed from July 29 to Sept. 10 in at least 17 states.Listeria is a common bacterium that typically causes mild illness in healthy people, but can cause severe illness in older people and those with compromised immune systems. It also can cause miscarriages and stillbirths in pregnant women and severe infections in new babies.Listeria infections lead to about 1,600 serious illnesses each year and about 260 people die, according to the CDC.The CDC estimates that about 48 million people in the U.S. each year get sick from tainted food, with about 128,000 hospitalized and 3,000 deaths.

WASHINGTON, July 8 (Xinhua) -- U.S. President Barack Obama on Friday hailed space shuttle Atlantis' final flight in NASA's shuttle program, saying Americans across the country watched with pride as America reached for the heavens once more.Obama expressed his "sincere gratitude" to Atlantis astronauts and space workers because they "helped our country lead the space age.""Today's launch may mark the final flight of the space shuttle, " Obama said in a statement. "But it propels us into the next era of our never-ending adventure to push the very frontiers of exploration and discovery in space."Friday's flight is the 33rd voyage for Atlantis. Its return to the earth later this month will mark the end of the 30-year shuttle program."What a truly awesome day today," said NASA Associate Administrator for Space Operations Bill Gerstenmaier at the STS- 135 postlaunch news conference. "What you saw is the finest launch team and shuttle preparation teams in the world.""It truly was an awesome, spectacular launch," added Kennedy Space Center Director Bob Cabana, who looked ahead to plans for future development beyond the shuttle program as space station operations continue.Atlantis will be the last shuttle to be retired. Discovery was first in March, followed by Endeavour at the beginning of June. Each shuttle will head to a museum.When the U.S. space shuttle program officially ends later this year, the Russian space program's Soyuz capsule will be the only method for transporting astronauts to and from the station.

BEIJING, June 12 (Xinhua) -- A senior Chinese official has called the country's police to better serve the people when the Communist Party of China (CPC) is meeting the 90th founding anniversary.Zhou Yongkang, member of the Standing Committee of the Political Bureau of the CPC Central Committee, made the remark on Sunday evening in meeting with top 10 favorite police officers selected through a nationwide vote.The Ministry of Public Security (MOPS) and the China Central Television have jointly conducted My Favorite Police Officer Competition in the past eight years.This year's winners include 75-year-old detective Wu Guoqing, network security police officer Li Qing from Jiangsu Province, traffic police officer Wu Hao of Miao Nationality from Hunan Province, female SWAT team leader Pan Qin from Guizhou Province.Zhou said that this year's competition attracted more than 150 million online voters which means more and more people are supporting the activity, and all winners should cherish the honor and better serve the people on their own posts.The official called on police officers around the country to learn from the 10 favarite officers and other winners in the competition who have all made outstanding contribution to the security of the people and society.

来源：资阳报