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LOS ANGELES, May 30 (Xinhua) -- The American Academy of Pediatrics (AAP) warned on Monday that children should keep away from energy drinks which may be dangerous for minors.The AAP urged young children and teens to avoid energy drinks entirely, saying routine consumption of sports drinks should be limited or eliminated.Energy drinks include such popular brands as Red Bull, AMP and Rockstar, the AAP said in a report.These drinks, the report said, tend to be heavily caffeinated, potentially having several times the level of caffeine found in a cup of coffee.In addition, manufacturers often add sugar and herbal stimulants such as guarana and taurine to the drinks, which are popular among kids, according to the report."There's no place for energy drinks for kids," said report co-author Dr. Marcie Beth Schneider, an adolescent physician in Greenwich, Connecticut. "There's a place for sports drinks, but that place is very specific."The caffeine in energy drinks can lead to high blood pressure, high heart rate and insomnia, she said.The other ingredients can boost the power of the caffeine, she said, adding that the drinks will have a greater effect on children because they're smaller than adults."Kids don't need to have this," she said. "This is not something they should be drinking."Schneider declined to identify any energy drinks that may be better than others for kids who insist on drinking them. If kids use energy drinks because they're tired, she said, they should get more rest instead of chugging caffeine.Half of the nation's 5,448 reported caffeine overdoses in 2007 were in people under age 19, although it's not known how many of the cases were the result of energy drink consumption, according to statistics provided by the AAP.

WASHINGTON, July 5 (Xinhua) -- Adhering to a healthy lifestyle, including not smoking, exercising regularly, having a low body weight and eating a healthy diet, appears to lower the risk of sudden cardiac death (SCD) in women, according to a study to be published Wednesday in the Journal of the American Medical Association."Sudden cardiac death (defined as death occurring within one hour after symptom onset without evidence of circulatory collapse) accounts for more than half of all cardiac deaths, with an incidence of approximately 250,000 to 310,000 cases annually in the United States," the authors write as background information in the study.Using data collected as part of the Nurses' Health Study, Stephanie Chiuve, of Brigham and Women's Hospital and Harvard Medical School, and colleagues examined the association between a healthy lifestyle and risk of SCD.A total of 81,722 women who participated in the Nurses' Health Study from June 1984 to June 2010 were included in the new study, and lifestyle factors were assessed via questionnaires every two to four years. A low-risk lifestyle was defined as not smoking, having a body mass index (BMI) of less than 25, exercise duration of 30 minutes/day or longer, and consuming a diet closely related to a Mediterranean-style diet (emphasizes high intake of vegetables, fruits, nuts, legumes, whole grains and fish, with moderate alcohol intake).During the 26 years of follow-up, there were 321 cases of SCD among women (average age 72 years at the time of the SCD event) in the study. All four low-risk factors were significantly and independently associated with a lower risk of SCD. Not smoking, exercising and eating a healthy diet each were inversely associated with risk of SCD. BMI also was associated with the risk of SCD, with women having a BMI between 21 and 24.9 at lowest risk.Women at low risk for all four lifestyle factors had a 92 percent lower risk of SCD when compared with women at low risk for none of the four lifestyle factors."In this cohort of female nurses, adherence to an overall healthy lifestyle was associated with a lower risk of SCD and may be an effective strategy for the prevention of SCD," the authors write.

WASHINGTON, Aug. 2 (Xinhua) -- The weakness of aging is associated with leaky calcium channels inside muscle cells and a drug already in Phase II clinical trials for the treatment of heart failure might plug those leaks, according to a report published Tuesday in the online edition of Cell Metabolism.Earlier studies by the research team led by Andrew Marks of Columbia University showed the same leaks underlie the weakness and fatigue that come with heart failure and Duchenne muscular dystrophy."It's interesting, normal people essentially acquire a form of muscular dystrophy with age," Marks said. "The basis for muscle weakness is the same." Extreme exercise like that done by marathon runners also springs the same sort of leaks, he added, but in that case damaged muscles return to normal after a few days of rest. A microscopic view shows smooth muscle cells derived from human embryonic stem cells showing the nuclei (blue) and proteins of the cytoskeleton (green) in this handout photo released to Reuters by the California Institute for Regenerative Medicine, March 9, 2009The leaks occur in a calcium release channel called ryanodine receptor 1 (RyR1) that is required for muscles to contract. Under conditions of stress, those channels are chemically modified and lose a stabilizing subunit known as calstabin1.Calcium inside of muscle cells is usually kept contained. When it is allowed to leak out into the cell that calcium itself is toxic, turning on an enzyme that chews up muscle cells. Once the leak starts, it's a vicious cycle. The calcium leak raises levels of damaging reactive oxygen species, which oxidize RyR1 and worsen the leak.The researchers made their discovery by studying the skeletal muscles of young and old mice. They also showed that 6-month-old mice carrying a mutation that made their RyR1 channels leaky showed the same muscular defects and weakness characteristic of older mice.When older mice were treated with a drug known as S107, the calcium leak in their muscles slowed and the animals voluntarily showed about a 50 percent increase in the amount of time spent wheel running. Now in clinical trials for patients with heart failure, the drug is known to work by restoring the connection between costabilin and RyR1.Despite considerable effort to understand and reverse age- related muscle wasting, there are no established treatments available. The new work suggests there may be hope in approaching the problem from a different angle."Most research has focused on making more muscle mass," Marks said. "What's different here is that we are focused not on muscle mass but on muscle function. More muscle doesn't help if it is not functional."

WELLINGTON, July 26 (Xinhua) -- Children born early are less likely to develop serious behavioral problems than previously thought because previous studies may have relied too much on the opinions of "sensitive" parents, according to a controversial New Zealand research.The study by the Child Development Research Group at the University of Canterbury looked at the emotional and behavioral adjustment of children born very preterm (VPT).It showed that by age 6 children born very preterm (less than 33 weeks) were at an increased risk of emotional and attentional problems when compared with their full term peers, said a statement from the university.However, the findings suggested the risks may be lower than previous studies had suggested, because previous studies primarily relied on parents to provide information on their children's conditions, said lead author Samudragupta Bora."While parents are an important source of information about their child, it is also important to gather information from other significant people in the child's life such as their classroom teacher," said Bora.Bora and other members of the research team, found that parents reported higher rates of emotional and attention problems in their children than teachers did."Having a baby born prematurely is an extremely stressful experience for parents. During their baby's stay in the neonatal unit most parents will have been alerted to the possibility of their child developing problems such as behavioral difficulties in the future due to being born too early. Therefore, very understandably, many parents of these children are very sensitive to the possibility of developmental problems," he said."The use of multiple informants - parents, teachers and clinical observation - to assess VPT children's well-being is important to minimize the effects of report source bias and the over or under-identification of adjustment problems in children born VPT," said Bora."This is controversial because it shows that reliance on parents or teachers alone can lead to data validity issues."Although children born VPT were at higher risk of showing emotional and attentional problems, the risks of more severe problems were relatively modest, said Bora.The findings have been published the Journal of Paediatrics and Child Health.

BEIJING, Aug. 13 (Xinhua) -- Chinese rating agency Dagong Global Credit Rating Co. on Saturday defended its AAA rating given to the Ministry of Railways, which has been under public fire over a train collision last month.The ministry received the long-term credit rating after launching on Monday its first bond sales since the crash on July 23 that killed 40 people near the Wenzhou city of eastern Zhejiang province.It sold 20 billion yuan worth of three-month bills on offer in the interbank market, with a yield of 5.55 percent, a relatively high rate for short-term government paper.The rating was assigned because of the ministry's status as a government agency backed by the central government revenue, its sufficient capital flows and strong financing ability, Dagong said in an email to Xinhua.The agency made the elaboration in response to market doubts as the ministry is already heavily indebted and the accident has stirred up skepticism about the its credibility and the safety of fast-expanding railways.Adding to doubts is that the AAA rating of the ministry is even a notch above China's local currency debt rating of AA+, which was also rated by Dagong.Government data showed the ministry's debts exceeded 2 trillion yuan (313 billion U.S. dollars) as of the end of June, raising its debt ratio to 58.53 percent, slightly up from the end of the first quarter of this year.Dagong said in the statement that the debt-to-asset ratio is medium level, lower than the alert line for the ministry which is 75 percent.The ministry has large-scale assets of good quality and relatively large room for fund-raising, Dagong said.The ministry has "extremely strong" repayment ability as it is backed by the state's credit, Dagong said, referring it as one of the three authorities that are allowed to issue bonds, along with the Ministry of Finance and the People's Bank of China.In July, the ministry issued 20 billion yuan of one-year commercial papers with a coupon rate of 5.18 percent, but only 18.73 billion yuan of the total was bought.Analysts said it has become more difficult for the ministry to borrow money because of tightened market liquidity and concerns over the ministry's debt burden.China's top four banks said at the end of last month that they will continue to offer loans to the ministry based on market conditions and risk appraisal. Credit from the four largest state-owned banks including the Industrial and Commercial Bank of China and the Construction Bank of China has been the major source funding the construction of China's fast-growing railways in recent years.

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