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WASHINGTON, Dec. 7 (Xinhua) -- Drugs that affect the levels of an important brain protein involved in learning and memory reverse cellular changes in the brain seen during aging, according to an animal study published Wednesday in the Journal of Neuroscience. The findings could one day aid in the development of new drugs that enhance cognitive function in older adults.Aging-related memory loss is associated with the gradual deterioration of the structure and function of synapses (the connections between brain cells) in brain regions critical to learning and memory, such as the hippocampus.Recent studies suggested that histone acetylation, a chemical process that controls whether genes are turned on, affects this process. Specifically, it affects brain cells' ability to alter the strength and structure of their connections for information storage, a process known as synaptic plasticity, which is a cellular signature of memory.In the current study, Cui-Wei Xie, of the University of California, Los Angeles, and colleagues found that compared with younger rats, hippocampi from older rats have less brain-derived neurotrophic factor (BDNF) -- a protein that promotes synaptic plasticity -- and less histone acetylation of the Bdnf gene. By treating the hippocampal tissue from older animals with a drug that increased histone acetylation, they were able to restore BDNF production and synaptic plasticity to levels found in younger animals."These findings shed light on why synapses become less efficient and more vulnerable to impairment during aging," said Xie, who led the study. "Such knowledge could help develop new drugs for cognitive aging and aging-related neurodegenerative diseases, such as Alzheimer's disease," she added.
BEIJING, Nov. 5 (Xinhua) -- China said Saturday that positive and balanced outcomes were achieved at the sixth summit of the Group of Twenty (G20) held earlier this week in the southern French city of Cannes."All the sides were committed at the summit to further coordinating their macro-economic policies, stabilizing the financial market, prompting economic growth, improving global economic governance and working together to maintain the hard-won momentum of the economic recovery," said Ma Zhaoxu, spokesman of the Chinese delegation after President Hu Jintao returned from Cannes, where Hu and the leaders of other G20 members' met to tackle major issues affecting global economic recovery and financial stability.The Chinese spokesman mentioned the Declaration, the Communique and the Action Plan issued after the meeting as "three outcome documents" of the G20 Cannes summit.Ma said priority was given to the European sovereign debt issue at the meeting."All the sides noted that the European Union has recently put forward a new series of measures and ideas to address the sovereign debt issue and hope that these measures will help Europe to stabilize the financial market, overcome the current difficulties and spur the economic recovery and development," he said.The Cannes Action Plan approved at the summit was meant to coordinate the macro-economic policies of all the members to endorse economic recovery and summon market confidence, said the spokesman. "It (the passage of the Action Plan) fully displays the resolution of the G20 to work hand in hand to promote a robust, sustainable and balanced world economy."Ma also hailed the "important consensus" reached at the summit in terms of the reform of the international monetary and financial system, the vibration of commodity price, international trade and development among others."It was emphasized at the summit that to address the issue of development is a key task to advance the global economic recovery and growth in the future," he said.Ma said emerging economies played an "important and constructive" role during the G20 summit.The continuing economic growth of emerging nations have injected vitality into the stability and recovery of the world economy as the international financial market is striving in turmoil, he said.Developing countries, represented by the emerging ones in the G20, have become constructive participants of global economic governance, said the spokesman, "which is a great progress of the era and indicates an in-depth readjustment and a historic change in the international economic order," he added.
ting fuel and benefits to agriculture from extended growing seasons."Global mitigation leading to a low climate change future reduces costs to Canada in the long term. This reinforces the argument that Canada would benefit environmentally and economically from a post 2012 international climate arrangement that systematically reduced emissions from all emitters - including Canada - over time," the report says.It recommends cooperation between governments, scientists and businesses to find ways to mitigate climate change and adapt to it.Canada's Minister of the Environment Peter Kent said the government has a plan to deal with global warming issues, which will be announced next month."Our government has a plan, a very good plan, to meet our target of reducing greenhouse gases by 17 percent from 2005 base levels, by 2020," Kent told Canada's House of Commons Thursday afternoon."We are moving forward to reduce greenhouse gases and, at the same time, we are investing in programs to help Canadians adapt to climate change," Kent said."Today's report merely echoes what our government has long recognized; that is, the importance of adaptation to climate change," he added.Earlier this week, several hundred people protested the government's policy of exploiting the oil sands deposits in western Canada.Environmentalists have criticized the Canadian government for not working hard enough to reduce CO2 emissions. Last year, a coalition of global warming activists gave Canada the "Fossil of the Year" award for failing to implement the Copenhagen Accord.
SAN FRANCISCO, Oct. 5 (Xinhua) -- Apple co-founder and longtime Chief Executive Officer Steve Jobs passed away on Wednesday."Steve died peacefully today surrounded by his family," Jobs' family said in a statement."We are grateful for the support and kindness of those who share our feelings for Steve. We know many of you will mourn with us, and we ask that you respect our privacy during our time of grief," said the statement.Apple's website has changed to "Steve Jobs: 1955-2011," along with the most iconic picture in which the scraggly bearded charismatic visionary posed with one hand up to his chin.Photo taken on Oct. 5, 2011 shows photo of Steve Jobs on the front page of www.apple.com. Apple Board of Directors announced that co-founder and former Chief Executive Officer Steve Jobs passed away on Wednesday"Apple has lost a visionary and creative genius, and the world has lost an amazing human being," the company said in a statement. "Those of us who have been fortunate enough to know and work with Steve have lost a dear friend and an inspiring mentor. Steve leaves behind a company that only he could have built and this spirit will forever be the foundation of Apple."Apple are asking for "thoughts, memories and condolences" to be shared by emailing rememberingsteve@apple.com.Apple Board of Directors also said in a statement that "Steve's brilliance, passion and energy were the source of countless innovations that enrich and improve all of our lives. The world is immeasurably better because of Steve."According to a memo sent by CEO Tim Cook, Apple is planning a celebration of Jobs' life for employees that will take place soon.Jobs took a medical leave of absence earlier this year, the third in his battle with pancreatic cancer that began in 2004. On Aug. 24, he stepped down as Apple CEO, saying "I have always said if there ever came a day when I could no longer meet my duties and expectations as Apple's CEO, I would be the first to let you know. Unfortunately, that day has come."Jobs recommended former CEO Tim Cook take his place as CEO. On Tuesday, Cook gave his first product announcement as CEO unveiling the new iPhone 4S.
BEIJING, Nov. 22 (Xinhuanet) -- Global AIDS deaths and new HIV infections have each dropped 21 percent since the peak of the AIDS pandemic in 1997, according to a UN report released Monday.One major factor responsible for the result is that life-saving HIV treatments have become more popular and got to 1.35 million more people in 2010 than in 2009.In middle-income and underdeveloped nations, these treatments have saved 2.5 million lives since 1995."We have seen a massive scale-up in access to HIV treatment, which has had a dramatic effect on the lives of people everywhere," said Michel Sidibe, executive director of the U.N. AIDS program.However, 53 percent of people who need HIV/AIDS treatments -- about 7.6 million people -- cannot get them, which accounted for 1.8 million AIDS deaths in 2010.There are now 34 million people living with HIV. And just in last year there were 2.7 million new infections.The decline in deaths and new infections means the AIDS pandemic is at a turning point, the UNAIDS report argues, adding smart investment can save millions of future deaths.