濮阳东方男科收费咨询濮阳东方医院看妇科病评价高专业,濮阳东方医院男科治早泄技术很权威,濮阳东方妇科技术值得信任,濮阳市东方医院口碑很好放心,濮阳东方医院看早泄可靠,濮阳市东方医院值得选择,濮阳东方医院做人流收费合理

A pinch in the leg, a squeal and a trickle of tears. One baby after another in Malawi is getting the first and only vaccine against malaria, one of history’s deadliest and most stubborn of diseases.The southern African nation is rolling out the shots in an unusual pilot program along with Kenya and Ghana. Unlike established vaccines that offer near-complete protection, this new one is only about 40% effective. But experts say it’s worth a try as progress against malaria stalls: Resistance to treatment is growing and the global drop in cases has leveled off. With the vaccine, the hope is to help small children through the most dangerous period of their lives. Spread by mosquito bites, malaria kills more than 400,000 people every year, two-thirds of them under 5 and most in Africa.Seven-month-old Charity Nangware received a shot on a rainy December day at a health clinic in the town of Migowi. She watched curiously as the needle slid into her thigh, then twisted up her face with a howl.“I’m very excited about this,” said her mother, Esther Gonjani, who herself gets malaria’s aches, chills and fever at least once a year and loses a week of field work when one of her children is ill. “They explained it wasn’t perfect, but I feel secure it will relieve the pain.”There is little escaping malaria -- “malungo” in the local Chichewa language -- especially during the five-month rainy season. Stagnant puddles, where mosquitoes breed, surround the homes of brick and thatch and line the dirt roads through tea plantations or fields of maize and sugar cane. In the village of Tomali, the nearest health clinic is a two-hour bike ride away. The longer it takes to get care, the more dangerous malaria can be. Teams from the clinic offer basic medical care during visits once or twice a month, bringing the malaria shot and other vaccines in portable coolers. Treating malaria takes up a good portion of their time during the rainy season, according to Daisy Chikonde, a local health worker.“If this vaccine works, it will reduce the burden,” she said.Resident Doriga Ephrem proudly said her 5-month-old daughter, Grace, didn’t cry when she got the malaria shot.When she heard about the vaccine, Ephrem said her first thought was “protection is here.” Health workers explained, however, that the vaccine is not meant to replace antimalarial drugs or the insecticide-treated bed net she unfolds every night as the sun sets and mosquitoes rise from the shadows. “We even take our evening meals inside the net to avoid mosquitoes,” she said.It took three decades of research to develop the new vaccine, which works against the most common and deadly of the five parasite species that cause malaria. The parasite’s complex life cycle is a huge challenge. It changes forms in different stages of infection and is far harder to target than germs.“We don’t have any vaccines against parasites in routine use. This is uncharted territory,” said Ashley Birkett, who directs PATH’s Malaria Vaccine Initiative, a nonprofit that helped drugmaker GlaxoSmithKline develop the shot, brand-named Mosquirix. The bite of an infected mosquito sends immature parasites called sporozoites into the bloodstream. If they reach the liver, they’ll mature and multiply before spewing back into the blood to cause malaria’s debilitating symptoms. At that point, treatment requires medicines that kill the parasites.Mosquirix uses a piece of the parasite — a protein found only on sporozoites’ surface — in hopes of blocking the liver stage of infection. When a vaccinated child is bitten, the immune system should recognize the parasite and start making antibodies against it.Scientists also are searching for next-generation alternatives. In the pipeline is an experimental vaccine made of whole malaria parasites dissected from mosquitoes’ salivary glands but weakened so they won’t make people sick. Sanaria Inc. has been testing its vaccine in adults, and is planning a large, late-stage study in Equatorial Guinea’s Bioko Island.And the U.S. National Institutes of Health soon will start initial tests of whether injecting people periodically with lab-made antibodies, rather than depending on the immune system to make them, could offer temporary protection during malaria season. Think of them as “potentially short-term vaccines,” NIH’s Dr. Robert Seder told a recent meeting of the American Society of Tropical Medicine and Hygiene.For now, only babies in parts of Malawi, Kenya and Ghana are eligible for the Mosquirix vaccine. After the vaccine was approved in 2015, the World Health Organization said it first wanted a pilot roll-out to see how well it worked in a few countries — in real-world conditions — before recommending that the vaccine be given more widely across Africa. “Everyone is looking forward to getting it,” said Temwa Mzengeza, who oversees Malawi’s vaccine programs. Those eager for the shots include her husband, whom she had to stop from trying to get them, she said.Mzengeza used to come down with malaria several times a year until she started following her own advice to sleep under a net every night. Unlike many other kinds of infections, people can get malaria repeatedly, building up only a partial immunity.In the pilot program that began last year, 360,000 children in the three countries are meant to be vaccinated annually. The first dose is given at about age 5 months and the final, fourth booster near the child’s second birthday.Experts say it is too early to know how well the vaccine is working. They’re watching for malaria deaths, severe infections and cases of meningitis, something reported during studies but not definitively linked to the vaccine.“To do something completely new for malaria is exciting,” said researcher Don Mathanga, who is leading the evaluation in Malawi. The rainy season has brought new challenges, making some rural roads impassable and complicating efforts to track down children due for a shot. So far in Malawi, the first dose reached about half of the children targeted, about 35,000. That dropped to 26,000 for the second dose and 20,000 for the third. That’s not surprising for a new vaccine, Mzengeza said. “It will pick up with time.”At the health clinic in Migowi in Malawi’s southern highlands, workers see signs of hope. Henry Kadzuwa explains the vaccine to mothers waiting at the clinic. He said there was a drop in malaria cases to 40 in the first five months of the program, compared to 78 in the same period in 2018.Even though he wishes his 3-year-old daughter, Angel, could receive the vaccine, “it’s protecting my community. It also makes my work easier,” Kadzuwa said. The Migowi area has one of the country’s highest rates of malaria, and a worn paper register in the clinic’s laboratory lists scores of cases.At the clinic, Agnes Ngubale said she had malaria several years ago and wants to protect her 6-month-old daughter, Lydia, from the disease.“I want her to be healthy and free,” she said. “I want her to be a doctor.”And she has memorized the time for Lydia’s second dose: “Next month, same date.”___Neergaard reported from Washington.___The Associated Press Health and Science Department receives 7200

A shooting at a bowling alley late Friday left three men dead and four people wounded in Southern California, and police are trying to find whoever fired the shots, authorities said.The gunshots at the Gable House Bowl in Torrance went off just before midnight. A fight -- first involving young ladies, then men -- happened shortly beforehand, sending people running, a witness said."Then ... maybe a minute and a half later, all of the sudden all we heard was, pop, pop, pop," the witness, Dana Scott, told RMG News. "Bowlers were diving under the benches. The people that were still bowling on the lanes were on the floors, underneath the seats.""People were looking for their parents, because this is a family league. You've got mothers, fathers, sons, daughters ... everybody's friends in that league," she said.No arrests were immediately reported after the shooting. City police were "working to identify the suspect(s) involved," they said in a news release.By late Saturday morning, relatives of those who were shot were clustered outside the bowling alley, standing behind yellow police tape. Some of them embraced one another; others looked toward the building's rear, where a coroner's van pulled out.Keithnisha More, one of those standing outside Saturday, said her brother-in-law was one of those who died and that he leaves behind a son."How do you explain to a 5-year-old boy that his father is dead?" More said. "How does my sister-in-law tell this little boy that daddy is gone? Just gone."The names of the dead and wounded weren't immediately released.Witness: 'People started to run'A man who says he was in a karaoke area of the building when the shooting happened described a scene of panic."People started to run inside the karaoke (area), shouting, 'Gunshot, gunshot, gunshot,'" the man, identified on Facebook as D Ryon Thomas, says in a video posted to the social network.Staff ushered people into an area in the back of the building, he said.Police ask public for videoDetectives are going to examine surveillance video recorded inside the building, Torrance police Sgt. Ron Harris said."We're also asking anyone in the public who might have seen anything, or (recorded) any cell phone video or other video, to come forward and help in this investigation," Harris said.Torrance police officers saw multiple people with gunshot wounds when they arrived, and they started lifesaving measures, including CPR and using a defibrillator, police said in a news release.Video from RMG News showed numerous firefighters or other first responders tending to people outside.The Gable House Bowl is open until 3 a.m. on Saturdays. The complex also offers laser tag and a bar, its website says.Torrance is about 20 miles from Los Angeles. 2763

A student gunman opened fire at a southern California high school Thursday morning, leaving two dead and several others injured, officials said.According to authorities, the male suspect, who is a student at the school, opened fire in the quad at Saugus High School in Santa Clarita around 7:38 a.m. before classes started. Authorities were on scene by 7:40 a.m. after receiving several 911 calls about the shooting. The suspected gunman shot and killed two students, a 16-year-old female a 14-year-old male, and injured three others before shooting himself in the head, police said. He is currently in custody and being treated at a local hospital, according to Los Angeles County Sheriff Alex Villanueva. Officials say he is in grave condition.Video obtained at the scene showed the suspect taking a .45-caliber semi-automatic pistol from a backpack before shooting the five other students and then himself, said Capt. Kent Wegener of the Los Angeles County Sheriff's Department.The other victims include two females, ages 14 and 15, and a 14-year-old male, police said. They were transported to local hospitals with gunshot wounds.Police are investigating the alleged shooter's home, which is near the school, authorities said at a press conference. Officials also said that Thursday was the student gunman's 16th birthday.The suspected shooter's mother and girlfriend are being interviewed by detectives. Other student witnesses are also still providing information to police.Other schools in the district were placed on lockdown amid the shooting. Police say they still don't have a motive in the shooting.EDITOR'S NOTE: A previous version of this story said that three people were killed based on a report from ABC News. ABC News is no longer reporting that three students have died, and this story has been updated to reflect ABC's reporting. 1862

A new pop-up called The Kitten Lounge is now open in D.C. It gives cat lovers the chance to hang out with kittens, while giving them the opportunity to save lives. “Really, I would describe this place as your chic best friend’s apartment filled with cats, but it’s like cool and trendy," says Kanchan Singh, who created the pop-up lounge. At The Kitten Lounge, 25 kittens roam free. The kittens are between the ages of three and six months, and visitors pay to hang out and play or relax with them.Singh owns 521

After years of development in the desert north of Los Angeles, a gigantic, six-engined megajet with the wingspan of an American football field flew Saturday morning for the first time.Stratolaunch Systems, the company founded in 2011 by the late Microsoft co-founder Paul Allen, conducted the first test flight of the world's largest plane.Basically, 362