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WASHINGTON, March 4 (Xinhua) -- New data suggest that the epilepsy drug Topamax (topiramate) and its generic versions increase the risk for the birth defects cleft lip and cleft palate in babies born to women who use the medication during pregnancy, the U.S. Food and Drug Administration (FDA) said Friday in a statement.Before prescribing topiramate, approved to treat certain types of seizures in people who have epilepsy, health care professionals should warn patients of childbearing age about the potential hazard to the fetus if a woman becomes pregnant while using the drug, the FDA said.Topiramate also is approved to prevent migraine headaches, but not to relieve the pain of migraines."Health care professionals should carefully consider the benefits and risks of topiramate when prescribing it to women of childbearing age," said Russell Katz, director of the Division of Neurology Products in the FDA's Center for Drug Evaluation and Research. "Alternative medications that have a lower risk of birth defects should be considered."Cleft lip and cleft palate, collectively called oral clefts, are birth defects that occur when parts of the lip or palate do not completely fuse together early in the first trimester of pregnancy, a time when many women do not know they are pregnant.The defects range from a small notch in the lip to a groove that runs into the roof of the mouth and nose, possibly leading to problems with eating, talking, and to ear infections. Surgery often is performed to close the lip and palate and most children do well after treatment.Data from the North American Antiepileptic Drug (AED) Pregnancy Registry indicate an increased risk of oral clefts in infants exposed to topiramate during the first trimester of pregnancy. Infants exposed to topiramate as a single therapy experienced a 1.4 percent prevalence of oral clefts, compared with a prevalence of 0.38 percent - 0.55 percent in infants exposed to other antiepileptic drugs.Infants of mothers who did not have epilepsy and were not being treated with other antiepileptic drugs had a prevalence of 0.07 percent. Similar data from the United Kingdom Epilepsy and Pregnancy Register supported the North American AED Pregnancy Registry data.According to the FDA, before starting topiramate, pregnant women and women of childbearing potential should discuss other treatment options with their health care professional.

BEIJING, Feb. 15 (Xinhua) -- Chinese Vice Premier Wang Qishan told a U.S. business delegation Tuesday that China would create a sound environment for business cooperation between the two countries.Praising the contribution of U.S. businesses to the sound development of China-U.S. relations, Wang said more exchanges between business people from the two countries would help promote bilateral trade cooperation.Chinese Vice Premier Wang Qishan (C front) poses for a group photo with members of a visiting U.S. business delegation headed by John Mack, chairman of Morgan Stanley, in Beijing, capital of China, Feb. 15, 2011. Executive chairman of Morgan Stanley and chief delegate John Mack said the U.S. business community would increase exchanges and cooperation with Chinese counterparts and play a positive role in the sound development of bilateral relations.The delegation, composed of the heads of many major U.S. companies, including General Motors, is visiting China from Feb. 13 to 16 for unofficial exchanges with Chinese businesses, including China National Offshore Oil Corporation and CITIC Group, according to the China Council for the Promotion of International Trade.

BEIJING, Jan. 20 (Xinhua) -- Major foreign media have been positive in their coverage so far of Chinese President Hu Jintao's four-day visit to the United States, which began Tuesday.AP said Obama was lavishing the grandest of White House welcomes on Hu as the leaders of the two powers looked for common ground on economic and security issues without alienating their domestic audiences."I absolutely believe China's peaceful rise is good for the world, and it's good for America," Obama said.The Washington Post said Obama stated several times that the United States does not fear a stronger China and that Washington has no interest in blocking Beijing's emergence as a superpower.Chinese President Hu Jintao speaks at a welcoming ceremony held by U.S. President Barack Obama on the South Lawn of the White House in Washington, the United States, Jan. 19, 2011It also said Hu's visit, in addition to serious policy matters, featured a fair amount of glitz. He arrived at the White House to a 21-gun salute and was sent off with a state dinner.The Wall Street Journal said President Obama is looking to assure Americans that they should not fear China's economic rise, using Chinese President Hu's high-profile state visit to announce job-creating business deals worth billions of dollars to U.S. companies.The two sides played down differences and stressed areas of cooperation, ranging from a plan to cooperate on nuclear security to an extension of the loan of two Chinese pandas to Washington's zoo.CNN said at a joint news conference held by the two leaders, Obama praised a "spirit of cooperation that is also friendly competition." President Hu told reporters the countries' relationship is based on "mutual respect and mutual benefit."Obama stressed common interests between the nations while toasting the Chinese leader at the White House, CNN said.VOA said dozens of business deals this week will increase U.S. exports by more than 45 billion U.S. dollars and increase China's investments in the United States by several billion dollars.AFP said that, during Hu's visit, the United States and China had announced a raft of trade deals worth 45 billion dollars. The deals, spanning sectors as diverse as agriculture, gasification, railways and hybrid buses, would support 235,000 U.S. jobs."The scope of Wednesday's deals were seen as evidence of the rapidly deepening business links between the two countries," AFP said.The Los Angeles Times said in its report that two leaders "unapologetically acknowledged major differences on economic issues and human rights" in a White House summit Wednesday, but also pledged cooperation to stabilize relations between the world's two largest economies.Obama said the United States hoped to benefit from China's "rapid and peaceful" growth, the report said.The Times of India said, "China's President Hu Jintao arrived in Washington on Tuesday on a four-day U.S. visit that is being watched in every capital on the planet."O Estado de S. Paulo, a local daily newspaper in Brazil, quoted President Hu's words, saying that China and the United States "stand to gain from a sound China-U.S. relationship, and lose from confrontation," thus they needed to discard the "Cold War mentality."The newspaper also said the two nations both hoped to take the visit as an opportunity to rebuild mutual trust despite some frictions over the past year.

TOKYO, March 20 (Xinhua) -- Traces of radioactive iodine had been detected in Tokyo and the surrounding Kanto region, according to the results of an investigation of radioactivity in precipitation and dust conducted by the government, local media reported on Sunday.Radioactive iodine was found in Tokyo, Saitama, Chiba, Yamanashi, Tochigi and Gunma prefectures, the Kyodo News said, citing the Ministry of Education, Culture, Sports, Science and Technology. The ministry added that the levels detected in the investigation alone would not affect human health.An employee of Yamagata city office holds a Geiger counter to detect radiation when evacuees from the vicinity of Fukushima nuclear plant wish to be screened upon their arrival at an evacuation centre set in a gymnasium in Yamagata, northern Japan March 19, 2011, eight days after Japan's devastating earthquake and tsunami.The investigation was carried out following the nuclear crisis at the Fukushima Daiichi nuclear power plant, the government said Sunday.The ministry said that a separate research has already shown that radioactive materials in the air and tap water in Tokyo and the five prefectures pose no threat to human health, according to Kyodo News report.

JINAN, Feb. 3 (Xinhua) -- Chinese Premier Wen Jiabao on Wednesday and Thursday visited drought-hit villages and ordered all-out efforts to combat the dry spell while celebrating the Chinese New Year with local people.When visiting Jiaxiang County and Qufu City in east China's Shandong Province, Wen inspected cornfields and reservoirs to assess the drought's impact.The drought, which began in October, has hit the southwest parts of Shandong hardest."It's hard to know when it will rain. We must prepare for the worst and do our best to combat the drought to ensure a good harvest," Wen said while visiting a reservoir in Qufu.Wen made the remarks Wednesday afternoon after learning the reservoir was holding a volume of water 8 million cubic meters less than normal.He told officials accompanying him any drought-caused reduction in grain output may undermine the government's top priority for 2011: the stabilization of prices.Officials at all levels must work to combat the drought, Wen added.China's central authorities last week announced an ambitious water conservancy project development plan, to raise China's ability to control flooding and drought.Under the plan, the average annual government spending on such projects will double the 2010 level."The drought affects agricultural output, which is related to the nation's food security and the income of rural people. I worry about it," Wen told a local farmer Wednesday morning.In the evening, Wen joined Liu Xianglun, 77, and his family at their house to make dumplings to eat to welcome the Chinese New Year.Before visiting Shandong, Wen visited farmers and workers in Dabieshan Mountain area, an old revolutionary base in east China's Anhui Province.The Spring Festival, China's Lunar New Year, falls on Thursday.