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One of the leading COVID-19 vaccine candidates produced virus antibodies in every patient tested in a trial conducted earlier this year, according to a report in the New England Journal of Medicine.The published results describe a successful Phase I testing for the vaccine, which is being produced by biotech company Moderna. The vaccine is currently in Phase II of testing, and Dr. Anthony Fauci said Tuesday that the vaccine would move to the third and final phase by the end of the month.According to the New England Journal of Medicine report, Phase I was conducted in 45 test subjects. Subjects were divided into three groups of 15, each of which was given different doses of the vaccine.Every subject received two shots, each administered 28 days apart.According to the New England Journal of Medicine, the vaccine "induced anti–SARS-CoV-2 immune responses in all participants."The Journal did note that half of the participants indicated they suffered from side effects that included "fatigue, chills, headache, myalgia, and pain at the injection site," most of which came after the second injection. Three of the participants who received the highest dosage of the vaccine reported at least one "severe" side effect.Fauci has said that the US is currently producing the top vaccine candidates with the hopes of distributing them when they are cleared for use by the FDA. He said Tuesday he remains "cautiously optimistic" that millions of doses of a vaccine will be available by January. 1504

Once a COVID-19 vaccine is approved by the Food and Drug Administration, it will face another hurdle before being distributed in California.Governor Gavin Newsom announced Monday he has created a scientific safety review workgroup who will “independently review the safety and efficacy of any vaccine that received FDA approval for distribution,” according to his office.The workgroup is part of California’s COVID-19 vaccine distribution plan, which was submitted to the CDC on Friday. Every state was asked to submit an initial distribution plan to the Centers for Disease Control and Prevention in anticipation of when a vaccine will be widely available. 665

OCEANSIDE, Calif. (KGTV) — A piece of cinema history located in North San Diego County will soon have a new home.The historic Graves House featured in the 1986 action flick "Top Gun" is being relocated and restored to make room for the Oceanside Beach Resort coming to the property.It's the first time the popular beach cottage rental, which was built about 137 years ago, will be moved.RELATED: Oceanside beach resort closer to construction after decade of delaysNot only is the home significant because it served as "Charlie's" home in the film, but it's a rare folk Victorian home, featuring architecture rarely seen nowadays.The home isn't moving far. It's already been relocated one block away for structural restoration. Afterward, it will be moved to the north side of the property on Pacific Street. There, cosmetic restoration and final touches will be completed once the overall hotel project is finished.Full restoration of the home will cost at least million and take about one and a half years.RELATED: Maverick lands in San Diego: Tom Cruise spotted on set of 'Top Gun' sequelIt's unclear who the tenant will be once the move and restoration is complete. Rumors have swirled it may become an ice cream parlor or coffee shop.“We’re looking at it as a really special kind of ice cream place so everyone can come in and get a 'top cone' from the Top Gun house," Senior Vice President of S.D. Malkin Properties Jeremy Cohen said in December.Save Our Heritage Organisation (SOHO), a nonprofit for local architectural and culturally significant landmarks, will spearhead preservation efforts for the home. 1624

On Thursday, March 8, all proceeds from beer sales at 10 Barrel Brewing Co. (1501 E St.) will be donated to the nonprofit Women Give San Diego. 151

On November 13, 2015, terrorists burst into the Bataclan concert hall and several restaurants across Paris, killing at least 130 and wounding hundreds more. Concertgoers and diners were raked by high-powered AK-47s, a cheaper, more primitive cousin of America's popular weapon of choice, the AR-15.Most of these weapons came from Germany and neighboring Belgium -- the bulk of them purchased via internet and mail orders originating in Eastern Europe and the Balkans.None of them was purchased in France, where authorities?have implemented some of the strictest laws and regulations in Europe. And while the black market certainly poses a threat to gun control, it's also clear that France's laws have made significant strides in counteracting many of the dangers created by guns.In France, there is no preordained right to bear arms, absent rigid registration and surveillance of their use. So most modern attacks, excluding terrorist incidents involving weapons obtained from abroad, are undertaken by trucks, cars and even knives.In other words, mass shootings are not the norm in France. And the United States would benefit from closely examining French gun laws in order to reduce the risk of another mass shooting within its own borders.That said, the tradition of gun ownership is deeply embedded in many strata of French society. In the countryside, hunting is a way of life and leisure -- more prevalent than?golf or tennis as weekend recreation. In regions like Sologne, some of the great families of France have practiced hunting back to the Middle Ages. La chasse (the hunt) is the preferred weekend pastime.While gun ownership is allowed, the state takes great pains to make sure guns are not abused. For example, authorities do not make gun ownership easy. Firearms are divided into four categories. In Category A are real weapons of war. As is in the United States, the French can't own a tank or a fighter plane, nor any fully automatic weapon like an Uzi or a Kalashnikov. No exceptions.Category B includes any firearm with a barrel shorter than 18.5 inches and a removable magazine with capacity larger than three rounds. For these, you need a sports shooting license, which means active membership in a shooting club, presenting yourself at a firing range at least three times a year, and visiting a physician annually for a physical and mental certification that you are capable of owning a firearm.The procedure and all accompanying paperwork?must be presented every three years. In between, this license can be revoked in an instant by the local police. When this licensing went into effect several years back, anyone who did not want to go through all the steps had simply to turn in their weapons. As many as 500,000 were relinquished.Category C is a bit easier and includes most regular hunting weapons limited to three rounds. But each such arm -- pistol or long gun -- must be registered, its owner carrying a sports shooting or hunting license. For the latter, the owner must undertake a full day of exams on theory and practice covering safety, protected species, even dog breeds.And in none of these categories can such a weapon routinely be carried ready to fire. It must be locked and disassembled during transport to the shooting range or property where it's to be used for hunting.Finally, Category D includes lightly regulated items, such as pellet and paintball guns, pepper spray and deactivated, display weapons.These categories stem from the reality that the French people really don't like to be massacred, and the statistics support that. The total number of guns -- licit and illicit -- in private hands in France dropped from 19 million in 2006 to 10 million in 2016. The number of guns owned per 100 people plunged from 31.2 in 2006, when gun laws were suddenly tightened in France, to 14.96 in 2016. By contrast, the number of guns per 100 people in the United States is 101.05. In fact, France?isn't even in the top 10 for per capita gun ownership, a list with America as No. 1.Of course, France hardly exists in a vacuum and Europe recognizes that. With its porous borders, a transnational approach is needed. The EU Firearms Directive establishes the same four categories of weapons as used by the French. After that, it's up to the individual country to tighten restrictions further.Some have, but many -- particularly in the old regions of Eastern Europe -- have not. The reality is that a Kalashnikov or a rocket launcher can be bought for as little?as 0 to 0 in some countries of the EU, according to Europol, the European Union's law enforcement agency. It is then up to individual countries to keep them from getting into their country and especially into the wrong hands.France has been among those at the forefront of the efforts to stop both the import and circulation of these weapons. And the mandate clearly begins at the top. French President Emanuel Macron recognized that reality, and has moved to sharply expand stop-and-arrest powers of the police, further tightening the removal of weapons from all individuals on terrorism watch lists. "We're sizing up the situation," said?Macron's Interior Minister Gérard Collomb, "and taking the weapons away."The French, years after gun laws have been tightened, appear to still support gun control measures. And why shouldn't they? The number of mass shootings in France is quite small. 5526

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