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SAN DIEGO (KGTV) — As Pfizer’s COVID-19 vaccine rolls out to healthcare workers, at least four have had severe allergic reactions after getting the shot.The cases include two healthcare workers in Alaska and two in the UK. In the UK cases, both individuals carried epipens.“So these were people with a history of severe allergies and not just severe allergies like you got hives, but they had allergies where they encounter certain things in the environment and their body shuts down,” said UC San Francisco infectious disease expert Dr. Peter Chin-Hong.All four have apparently recovered.At this point, doctors aren’t sure what caused the reactions. Generally speaking, allergies when your immune system overreacts to something harmless.Pfizer’s vaccine has 10 ingredients that fit into four categories.The active ingredient is mRNA. These are temporary genetic instructions for your cells to build a small, harmless fragment of the virus’ shell to train your immune system, similar to setting up a punching bag to train a boxer.Then there are fats to stabilize and transport the mRNA, salts to maintain the pH, and sugar to prevent the solution from degrading while freezing.All the ingredients are considered standard. Dr. Chin-Hong says he was struck by what’s not in the vaccine.“They didn't have egg products or any of those kinds of things that people might be allergic to,” he said. “They didn't have live virus, which might also elicit a response.”The only ingredient with a history of allergic reactions is polyethylene glycol, or PEG, one of the fats that acts as an oily bubble for the mRNA.PEG is also in Moderna’s vaccine and it’s common; it’s found in ultrasound gel, laxatives, injectable steroids and other products.Although PEG allergies are rare, the FDA says people who are allergic to any of the 10 ingredients should not get the vaccine.However, experts say people with common allergies should not worry.“A lot of people have minor food allergies or bee-sting allergies or peanut allergies or environmental allergies,” said Dr. Christian Ramers of Family Health Centers of San Diego. “They may even carry an epi-pen because sometimes it gets severe. Those people would not be excluded from getting this vaccine.”The American College of Allergy, Asthma and Immunology issued guidance saying people with those common allergies, including to latex and medications, “are no more likely than the general public to have an allergic reaction” to the vaccine.After every shot, people who get vaccinated have to wait 15 minutes so healthcare workers can monitor them for a reaction. Should one occur, interventions like epi-pens are very effective.The FDA said people with a history of allergic reactions to vaccines or injectable drugs can still get the shot, but they should wait 30 minutes for slightly longer monitoring.The odds of having a severe allergic reaction to any vaccine is about 1 in 760,000. That means you’re more likely to be struck by lightning in a given year, which the CDC estimates is about 1 in 500,000. 3048

SAN DIEGO (KGTV) -- Authorities are investigating after an inmate died at the George Bailey Detention Facility. According to the San Diego County Sheriff’s Department, deputies were notified that an inmate identified as 63-year-old Dennis Lee Curry needed medical help inside his cell on May 11. Deputies say when they arrived, Curry complained of pain to his head and chest, but had no visible injuries. Curry was taken to a local hospital where his condition worsened and he was placed on life support before he died on the morning of May 13. Following an autopsy, it was discovered that Curry died of natural causes. The Sheriff’s Department’s homicide unit was called in to investigate, as they do with all in-custody deaths. Curry was in custody for outstanding warrants related to prior DUI and drug-related charges, according to the department. 860

SAN DIEGO (KGTV) - County health officials are encouraging local women to get vaccinated for "whooping cough" amid a possible epidemic.The county says pertussis, commonly known as "whooping cough," could turn into a possible local epidemic based on historical patterns."It’s critical for pregnant women and people who come into close contact with young infants to get vaccinated," Wilma Wooten, County public health officer, said. "Newborns are very susceptible to whooping cough because they are too young to be fully vaccinated. It is vital for pregnant women to be vaccinated in the third trimester to give protection to their unborn infants."So far in 2018, there have been 56 confirmed cases of pertussis.RELATED: This app says it can help you stay flu-freeLast year, San Diego County recorded at least 1,154 cases, the highest of any county in California. Wooten said the high numbers were partially attributed to reporting methods."Pertussis activity in our region appears to higher than the rest of the state, but much of this is due to the excellent detection and reporting of this potentially deadly disease by San Diego pediatricians and family physicians," Wooten said.Pertussis is a cyclical disease that peaks every three to five years, according to health officials. San Diego's last epidemics were in 2010 and 2014, with 1,179 and 2,072, respectively.RELATED: 20 more people died from the flu in San DiegoThe county said on in five of the San Diego County cases in 2017 were in individuals under three years of age, and 52 percent were between the ages of 10 and 17.The Centers for Disease Control and Prevention recommend a vaccination schedule to combat whooping cough: 1715

SAN DIEGO (KGTV) - Computers have become a lifeline to San Diegans during the pandemic and a new partnership between the city and non-profit San Diego Futures Foundation could make it easier for people in need to get connected.Executive Director of San Diego Futures Foundation Gary Knight said the need skyrocketed the first three weeks of the shut down in March, "we distributed over half our annual inventory in that three weeks."That's more than 1,500 computers. The non profit partners with companies like Qualcomm, General Atomics and San Diego County to take on their old computers, refurbish them and connect them with people in need.City of San Diego Digital Strategy Manager Jen Lebron said 30,000 households don't have a computer, just within the city limits.Right now that means limited connection to healthcare, education and job seeking material."San Diego Futures Foundation has an incredibly broad reach, that way we can get these computers in the hands of students, seniors, veterans, foster families and non profits that really need the help," Lebron said.Michelle Sanudo recieved a computer from SDFF this month and said it's made her feel independent and successful. She's a single mom who relied on the library to entertain her four and one-year-old children while she worked."Really it was kind of like a sanctuary, I would get to do my paperwork for school, also apply for jobs," Sanudo said."When they closed the libraries that's when it hit me." She said the computer allows her to order groceries so she can keep her family safe during the pandemic and pursue her dream of becoming a medical assistant.As the need for computers continues in San Diego and SDFF's inventory wanes, they need more donations. That's where the city is stepping in. For the past year the city has been vetting the non profit. Wednesday the City Council Economic Development and Intergovernmental Relations Committee unanimously approved the partnership. Now it must go before the full council to receive approval. The item is on the docket for Tuesday, the 21st."We are ready with nearly 2,300 computers that we can give to San Diego Futures Foundation." Lebron said these computers have been stockpiled, in hopes of being used to better the community.If approved, the city would hand over the stockpile and have about 800 computers each following year to supply SDFF.Those computers could be in the hands of people like Sanudo by mid-August."We're not going to see this disappearing, the need for this is going to stay at a very high rate for a while," Knight said as we head toward the school year.If you would like to donate your computer to SDFF, please call and make an appointment to do a drive by drop off.If you would like to see how you can get connected with a computer, please click here. 2810

SAN DIEGO (KGTV) -- As an active 45-year-old man who loves to surf and take adventures with his daughter, Bryce Olson was the last person his friends expected to get cancer.In 2014, a call while at work confirmed it: stage IV metastatic prostate cancer.Metastatic means the cancer has spread to other parts of the body, lymph nodes, bones or other organs.“It was just shocking and sad and I didn’t know anything about this stuff, so I just...I rolled into whatever my doctors were recommending," said Olson.He says the standard of care - surgery, chemotherapy, and the initial hormone therapy - wasn't working.“I started coming to terms with my own mortality. I didn’t even think I’d see my kid get out of elementary school and I was losing hope," said Olson.Olson says he wanted to make his final days count. The Intel employee started learning about precision medicine and eventually pursued DNA sequencing to find out exactly what was driving his disease.“I'm a believer in profiling your tumor at a molecular level and trying to understand what’s driving your unique disease, and then taking that data and then finding the right drug for the right person at the right time," said Olson.His results led him to a clinical trial in Los Angeles, where he was a perfect molecular match for the drug being tested.Four years later, Olson's precision medicine journey led him to San Diego's Epic Sciences.“We're actually going to a place where no test has gone before," said Murali Prahalad, President and CEO of Epic Sciences. "These are metastatic patients; the disease has already spread. And we’re trying to understand in the later stages of the disease when it’s far more complicated, how do you then understand which treatment is the right one.”Patients like Olson have two treatment options, chemotherapy or hormone therapy."It's very important to know which medicine is going to work," said Pascal Bamford, Chief Scientific Officer of Epic Sciences, "At the metastatic end of this disease every week, every day, every month is critically important."The company has created a blood test to make the choice easier, called the Oncotype DX AR-V7 Nucleus Detect.If the antigen AR-V7 is detected in a patient, they have built a resistance to hormone therapy, meaning chemotherapy would likely be a better treatment option.“We think it’s very groundbreaking, to say this is the first test that can tell a patient which drug to go on to extend their life," said Ryan Dittamore, Chief of Medical Innovation.Dittamore says the test helps provides certainty for doctors. Patients they've studied have almost doubled their life expectancy with the AR-V7 test.“It can mean the world, not only to patients but loved ones," said Dittamore.Olson was AR-V7 negative, meaning he could continue hormone therapy.Four months in, it's working. “I’m going to see my kid not only get out of high school but college and get married. I’m fully confident that I can do that because I’m just going to keep pushing," said Olson.In December 2018 the AR-V7 test will be covered by Medicare, meaning thousands of more men will have access to it. 3150

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