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LOS ANGELES, April 2 (Xinhua) -- People taking antidepressants may be more likely to develop thicker arteries which may raise the risk of heart disease and stroke, a new study suggests.Depression can heighten the risk for heart disease, but the effect of antidepressant use is separate and independent from depression itself, according to the study make public by the American Association for the Advancement of Science (AAAS) on Saturday.The data suggest that antidepressants may combine with depression for a negative effect on blood vessels, said study first author Amit Shah, MD, a cardiology fellow at Emory University School of Medicine.Study findings will be presented on April 5 at the American College of Cardiology meeting in New Orleans, according to the AAAS.The study included 513 middle-aged male twins who both served in the U.S. military during the Vietnam War. Twins are genetically the same but may be different when it comes to other risk factors such as diet, smoking and exercise, so studying them is a good way to distill out the effects of genetics.Researchers measured carotid intima-media thickness - the thickness of the lining of the main arteries in the neck -- by ultrasound. Among the 59 pairs of twins where only one brother took antidepressants, the one taking the drugs tended to have higher carotid intima-media thickness (IMT), even when standard heart disease risk factors were taken into account.The effect was seen both in twins with or without a previous heart attack or stroke. A higher level of depressive symptoms was associated with higher IMT only in those taking antidepressants."One of the strongest and best-studied factors that thickens someone's arteries is age, and that happens at around 10 microns per year," Shah said. "In our study, users of antidepressants see an average 40 micron increase in IMT, so their carotid arteries are in effect four years older."Antidepressants' effects on blood vessels may come from changes in serotonin, a chemical that helps some brain cells communicate but also functions outside the brain, Shah said."I think we have to keep an open mind about the effects of antidepressants on neurochemicals like serotonin in places outside the brain, such as the vasculature. The body often compensates over time for drugs' immediate effects," Shah said. " Antidepressants have a clinical benefit that has been established, so nobody taking these medications should stop based only on these results. This isn 't the kind of study where we can know cause and effect, let alone mechanism, and we need to see whether this holds up in other population groups."

BEIJING, Jan. 28 (Xinhua) -- China will further its efforts to harness the Huaihe River over the next five to 10 years in a bid to support the economic development of the regions along the river.The decision was announced Friday in a statement released after an executive meeting of the State Council, China's Cabinet, which was presided over by Premier Wen Jiabao.The work will include upgrading dams and water gates in flood diversion programs and building more irrigation and water conservancy projects in low-lying lands along the Huaihe River, said the statement.Further, efforts will be made to guard against water pollution and help urban and rural residents in the Huaihe River regions have sufficient access to clean water, it said.Also, more flood control reservoirs will be constructed, while more residents will be relocated from flood diversion areas as well as flood land.The cabinet urged government departments to earmark more funds and enhance management and cooperation in implementing these measures.The 1,000-kilometer Huaihe River, the third longest water way in China, originates from Mount. Taibai, central Henan Province, and runs eastward between the Yangtze River and the Yellow River, the two largest rivers in the country. It cuts through Henan and east China's Anhui and Jiangsu provinces before entering the Yangtze River via the Hongze Lake.The flood-prone river has a drainage area of about 180,000 square kilometers.

PYONGYANG, Feb. 14 (Xinhua) -- Kim Yong Nam, president of the Presidium of the Supreme People's Assembly of the Democratic People's Republic of Korea (DPRK), met Chinese Minister of Public Security Meng Jianzhu here on Monday.Kim said it was the consistent stand of the Worker's Party of Korea (WPK) and the government and the firm will of the people to develop the traditional DPRK-China friendship generation after generation.The DPRK is sincerely happy to see the great achievement China has made and wish that the Chinese people make even more progress, Kim said.Meng, also a State Councilor, said the traditional friendship between the two neighboring countries has strengthened through the ages. He expressed his expectations of inheriting the friendship, deepening communications and cooperation in various areas and promoting the China-DPRK friendship.Ri Yong Ho, Presidium of Political Bureau of Central Committee of WPK and chief of the Korean People's Army General Staff, also met Meng on the same day.Ju Sang Song, a member of the Political Bureau of Central Committee of the WPK and Minister of People's Security, met Meng on Sunday. The two achieved consensus on making more efforts to develop cooperation and communications on public security to make active contributions to the traditional China-DPRK friendship. An agreement on cooperation between the the two security ministries was signed after the meeting.Meng arrived at Pyongyang on Sunday at the invitation of Ju Sang Song.

SYDNEY, March 30 (Xinhua) -- Work is good for health while long term work absence, work disability and unemployment can make us miserable, according to a consensus statement from the Australian and New Zealand doctors on Wednesday.The Australian and New Zealand Consensus Statement on the Health Benefits of Work was launched by the Royal Australasian College of Physicians (RACP) and the Australasian Faculty of Occupational and Environmental Medicine (AFOEM) in Wellington.In the statement, doctors say that work is generally good for health and long term break form work along with unemployment and being unable to work due to disability generally have a negative impact on wellbeing.Work is also an effective means of reducing social exclusion, particularly for indigenous people and other disadvantaged groups, the statement says."Work practices, workplace culture, work-life balance, injury management programs and relationships within workplaces are key determinants, not only of whether people feel valued and supported in their work roles, but also of individual health, wellbeing and productivity," it said."Good outcomes are more likely when individuals understand the health benefits of work, and are empowered to take responsibility for their own situation." the statement said.

WASHINGTON, April 3 (Xinhua) -- Scientists have confirmed that metabolic syndrome, a constellation of conditions that increases the risk of heart disease and diabetes, may also increase the risk of the two most common types of liver cancer, according to data presented at the American Association for Cancer Research's 102nd Annual Meeting 2011, held in Orlando, Florida on April 2-6.Katherine McGlynn, a senior investigator at the National Cancer Institute, said approximately one-third of the U.S. population has metabolic syndrome, which is defined as the co-occurrence of at least three of the following five conditions: raised blood pressure, elevated waist circumference, low HDL or "good" cholesterol, raised triglyceride levels and raised fasting plasma glucose levels.According to McGlynn, persons with these conditions may be at increased risk of developing hepatocellular carcinoma and intrahepatic cholangiocarcinoma.For the current study, researchers identified 3,649 cases of hepatocellular carcinoma and 743 cases of intrahepatic cholangiocarcinoma. They compared the medical history of these patients with the medical histories of 195,953 cancer-free adults.Statistical analyses showed that the persons with liver cancer were significantly more likely than cancer-free persons to have a prior history of metabolic syndrome: 37.1 percent of patients with hepatocellular carcinoma had pre-existing metabolic syndrome, as did 29.7 percent of patients with intrahepatic carcinoma; only 17.1 percent of the cancer-free adults had metabolic syndrome.Liver cancer incidence has been rising since the 1980s in the United States. The factors related to the increase are not well understood. "A lot of attention has focused on viral risk factors, but a significant part of the increase may be due to metabolic syndrome, as well as to diabetes and obesity," said McGlynn."The prognosis for liver cancer is only marginally better than the prognosis for pancreatic cancer, with a five-year survival of approximately 10 percent," she said. "Prognosis is more favorable, however, when liver cancers are diagnosed at early stages when they are small and localized to the liver."

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