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WELLINGTON, June 7 (Xinhua) -- Scientists in New Zealand have developed a new drug to fight previously untreatable hypoxic cancer tumors, which form in areas of the body starved of oxygen.The researchers at the Auckland University have entered an agreement for the clinical development of CEN-209, which was developed over 10 years of research, said a statement from the university Tuesday.CEN-209 was designed to enhance the effectiveness of radiotherapy and chemotherapy in solid hypoxic tumors, which were resistant to standard cancer therapies, said the statement. In lung cancer patients for example, about half of tumors had hypoxic regions.The new drug worked by damaging the DNA of hypoxic cancer cells, while leaving normal, healthy tissues alone.CEN-209 was designed and created by researchers at the university's Auckland Cancer Society Research Centre (ACSRC), using computer models of drug transport within tumors to accurately predict the anti-tumor activity of the drugs."Our computer models of drug transport developed in-house allowed the synthetic chemists to test their design theories and considerably shortened the discovery process," said Associate Professor Michael Hay, who led the ACSRC research chemists."CEN-209 improves markedly on previous agents in this class in terms of its ability to penetrate tumors, and this is reflected by its improved activity in the laboratory, when combined with long or short courses of radiotherapy," said researcher Professor Bill Wilson.Under the agreement between the university's Auckland UniServices Ltd. and California-based Centella Therapeutics, Inc., a subsidiary of Varian Medical Systems, Inc., Centella will have exclusive rights to CEN-209, which it will develop and trial with Cancer Research UK.The work on CEN-209 is the culmination of a program initiated with funding from the U.S. National Cancer Institute, and more recently from the Maurice Wilkins Centre for Biodiscovery. Ongoing preclinical research on CEN-209 and a backup compound was funded by grants from the Auckland Medical Research Foundation, Genesis Oncology Trust and Health Research Council of New Zealand, said the statement.
SAN FRANCISCO, Sept. 12 (Xinhua) -- Amazon.com Inc. is talking with book publishers to launch a rental subscription service for digital books, U.S. media reported on Monday.Several publishing executives said they aren't enthusiastic about the idea because it could lower the value of books and it could also strain their relationships with other retailers that sell their books, The Wall Street Journal quotes people familiar with the matter in a report.The Seattle-based company is considering a digital book library featuring old titles, which would be available to Amazon Prime subscribers, who currently pay 79 U.S. dollars a year for access to digital library of movies and TV shows and unlimited two-day shipping, said the report.Amazon would offer book publishers a substantial fee and could limit the amount of books that Amazon Prime customers could read for free every month, the report cited some sources as saying.The online retailing giant makes the popular electronic reader Kindle and is also reported to launch a color touchscreen tablet before October to compete with Apple's iPad and other devices in the increasingly crowded tablet computer market.The proposal is another sign that retailers are looking for more ways to deliver content digitally as customers increasingly read book and watch TV on personal computers, tablets and other electronic devices, said The Wall Street Journal report.
WELLINGTON, Sept. 27 (Xinhua) -- New Zealand and Japanese scientists are teaming up to develop healthier foods under two government-funded "functional foods" projects.One project, to be led by New Zealand's Massey University, will work with New Zealand food companies to create and develop a functional food with specific health enhancing effects for menopausal women, New Zealand Science and Innovation Minister Wayne Mapp announced Tuesday.The other project, to be led in New Zealand by Plant and Food Research, would use mass spectrometry to develop a "metabolic atlas" of the chemical composition of allium vegetables, such as onions and garlic, which the horticultural industry could use to develop new food products with health benefits.Mapp said the two research projects would be awarded a total of 1 million NZ dollars (782,000 U.S. dollars) in funding to strengthen collaborative research relationships between New Zealand and Japan, Mapp said."These research projects have strong commercial potential, including through the Japanese market, and so have the potential to benefit our economy," said Mapp."The government is committed to building and strengthening research relationships with other countries that will achieve world-class scientific results and lead to new innovative technologies."The two projects awarded funding under Ministry of Science and Innovation's Japan Science and Technology Agency (JST) funding round focus on functional foods. The ministry and Japan each fund half the cost of each research project awarded funding.
BEIJING, Sept. 1 (Xinhua) -- Medicine prices at public clinics have been notably reduced thanks to a policy that promotes basic medicine, an office of the State Council said Thursday.Current price levels of basic medicine used by government-funded township hospitals and community clinics have been reduced an average of 25 percent from the levels two years ago when the policy started, according to a statement from the State Council office in charge of reforming the country's healthcare program.China has introduced a state list of basic medicine used by government-funded township hospitals and community clinics, which includes roughly 300 types of commonly-used Western and traditional Chinese medicine.Provincial governments will purchase basic medicine through public bidding and distribute them to local clinics.These clinics must not raise the prices of listed medicine and in return, the government will provide them with subsidies.The policy has been implemented at all township and community clinics in all the 31 provinces, municipalities and autonomous regions in the Chinese mainland, the statement said.
SAN FRANCISCO, June 13 (Xinhua) -- Google on Monday confirmed that it had signed an agreement to buy Admeld, an on-line advertising optimization firm, in a deal seen as the Internet search giant's latest move to bolster its on-line display ad business.Admeld, launched in 2007 and headquartered in New York City, has developed a service that can help on-line publishers manage their ad space more efficiently and profitably.Admeld now has more than 500 customers worldwide, among them are FOX News, IDG TechNetwork, Discovery and The Weather Channel, according to information posted on its website."By combining Admeld's services, expertise and technology with Google's offerings, we're investing in what we hope will be an improved era of flexible ad management tools for major publishers, " Neal Mohan, Google's vice president of display advertising, said in a blog post announcing the deal."We believe that this investment will be an important step to help on-line publishers, and will further improve and grow the display advertising industry as a whole," Mohan noted.On-line display ads usually appear in forms that consist of images and may be interactive. According to the Interactive Advertising Bureau, a U.S. trade association, display-related on- line ad revenue in the United States totaled nearly 10 billion U.S. dollars in 2010.Financial terms of the deal were not disclosed by the two companies. TechCrunch, a technology blog site, has reported that Google paid around 400 million dollars.