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The reboot of "Lizzie McGuire," which was to air on Disney+, is no longer happening.Actress Hilary Duff, who played the lead on the original Disney Channel series that ran from 2001 to 2004, announced on social media Wednesday that the reboot wouldn't happen despite everyone's best interests.In 2019, Disney announced they were relaunching the show. According to The Hollywood Reporter, after several delays, including the firing of creator and revival showrunner Terri Minsky, grounded production after they'd already shot two episodes.Original cast members Adam Lamberg, Hallie Todd, Robert Carradine, and Jake Thomas were set to reprise their roles as well, Variety reported.According to CNN, Duff made a public plea in February asking the series be moved to Disney-owned Hulu from Disney+ so that the show could be a more adult-friendly version. 858

The United Kingdom says it will be the first to conduct COVID-19 vaccine human challenge trials.It's different than other vaccine studies. People will be deliberately infected with the virus, which speeds up the research process.Pending approval, the process will start in January at a London hospital. It will require about 90 healthy young adults between the ages of 18 and 30.The group 1 Day Sooner has recruited from all over the world, including 3,000 Britons.“If the vaccine works, then ideally, people don't get infected and if people do, then they will be closely monitored and treated, but because these are young and healthy people taking part in the trial, I think, researchers feel comfortable doing so because the risks of death are on par with something like kidney donation for people who are young and healthy,” said Abie Rohrig with 1 Day Sooner.Before researchers test the vaccine, they'll do a characterization study. That's where volunteers are infected by getting a vaccine to determine the right amount of virus to give during the trial.Because of the risk, 1 Day Sooner is advocating for the entire process to be made public.Results could come in May. Even though that's likely after other COVID-19 vaccines are licensed, it's still important because we need billions of doses and because of the unique data human challenge trials provide.“Researchers can understand how the virus works in the human body. They can understand the biological markers of immunity. In fact, much of our understanding of other types of coronaviruses come from challenge studies that were conducted in the 1960s in Britain,” said Rohrig.Human challenge volunteers are paid and monitored for at least a year after. 1722

The U.S. surpassed the 14 million mark in confirmed cases of COVID-19 Thursday and set new records in both daily recorded cases and daily deaths as the country delves deeper into the bleakest stretch of the pandemic.On Thursday alone, Johns Hopkins says that the U.S. reported 2,879 deaths linked to COVID-19, and 217,664 more people were confirmed to have contracted the virus.Thursday marked the second straight day that the U.S. set a record in daily reported deaths. According to Johns Hopkins, at least 2,500 people have died of COVID-19 in the last three days.Thursday also marked a new record in daily reported cases of the coronavirus and the third day in the last week that the U.S. had reported more than 200,000 cases.Finally, Thursday marked an entire month (from Nov. 3 to Dec. 3) of at least 100,000 new cases of COVID-19 each day. Between Oct. 30 and today, more than 5 million Americans have contracted COVID-19 — a figure that represents 36 percent of all cases that have been recorded since the pandemic began.And as dire as the situation is today, health experts only expect the virus to spread further in the coming days. Millions of people boarded an airplane to travel this weekend, and health experts say the spread that occurred during the Thanksgiving holiday is just now being recorded in tests.Deaths are also a lagging statistic, meaning those figures will likely rise in the coming weeks. And with many hospitals already at capacity — the COVID Tracking Project reports that an all-time high 100,000 Americans across the country are fighting the virus in a hospital — some health care facilities may be forced to turn patients away. 1673

The University of Washington’s Institute for Health Metrics and Evaluation now projects that 33,000 American lives would be saved between now and October 1 by near universal wearing of masks.The IHME released the updated model on Wednesday.The IHME’s coronavirus projections have been frequently cited in the past by the White House’s coronavirus task force. The group uses state data along with other metrics to create projections on the number of coronavirus-related deaths throughout the US.The projection state that the US is currently on track to have an additional 58,000 coronavirus-related deaths between now and October 1. But that number drops to just 23,000 if masks are universally worn in public. Those figures are on top of the over 121,000 reported coronavirus-related deaths since the beginning of the pandemic.The IHME’s model projects that the US death toll will stay consistent on a per-day basis between now and September, before starting to increase in the fall. But the model projects that fewer than 100 Americans will die per day from coronavirus by September if masks are worn.The IHME’s latest model projects that coronavirus-related deaths will continue to surge in the states of Texas, Arizona and Florida in the coming weeks, while leveling or dropping off in many other states.To see a state-by-state breakdown of the IHME’s projections, click here.Last month, a study in the Lancet found that the use of masks and respirators by those infected with the virus reduced the risk of spreading the infection by 85%. The authors analyzed data that showed that N95 respirators in healthcare settings were up to 96% effective. Other masks were found to be 77% effective. 1701

The U.S. decline in cigarette smoking could be stalling while the adult vaping rate appears to be rising, according to a government report released Thursday.About 14% of U.S adults were cigarette smokers last year, the third year in a row the annual survey found that rate. But health officials said a change in the methodology make it hard to compare that to the same 14% reported for 2017 and 2018.The adult smoking rate last saw a substantial drop in 2017, when it fell from 16% the year before.The new figures from the Centers for Disease Control and Prevention mean there are more than 34 million adult smokers in the U.S.Meanwhile, about 4.5% of adults were counted as current e-cigarette users last year — about 11 million people.That rate appears to be up from 3.2% in 2018 and 2.8% in 2017. But again, officials said that comparing 2019 with earlier years is difficult because of the survey change.The CDC figures are based on responses from about 32,000 people.Health officials have long called tobacco use the nation’s leading cause of preventable disease and death.___The Associated Press Health & Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 1279

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