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SAN DIEGO (KGTV) — It has now been seven months since the pandemic began, and there are still a lot of questions about the best ways to treat patients with COVID-19.Researchers at UC San Diego are leading an effort to produce swift and reliable answers that could help doctors tailor treatments and hospitals plan bed space more efficiently.Doctors agree: the best way to fight any disease is to tailor the treatment for each individual based on their age, gender, race and other factors. But how does one doctor do that with a new disease like COVID-19, especially if their hospital has only seen a few hundred cases?“There might be some patterns you can get from 500 patients but there might be some others that you cannot,” said UCSD professor Dr. Lucila Ohno-Machado, chair of the Department of Biomedical Informatics.Dr. Ohno-Machado’s solution? Pool data.She’s leading the charge behind COVID19questions.org, a collaboration between 12 medical systems spanning more than 200 hospitals across the country.The collaboration includes several University of California health systems, the University of Texas Health Science Center at Houston, the University of Colorado Anschutz Medical Campus, and the largest organization in the cohort, the Veterans Affairs Healthcare System.“Each hospital is a little small to answer the questions. So by having it all together, we get the answers quicker,” said Ohno-Machado.They’re going after answers on how long patients with diabetes or cancer stay in the hospital, and whether COVID-19 is deadlier for smokers or non-smokers.Their findings revealed that men are much more likely to wind up on a ventilator than women.And they quantified just how much better we’ve gotten at treating COVID-19 over time.Since May 1, hospital stays among surviving patients have shrunk more than 10 days on average. That’s important for hospital managers planning and predicting bed space.“We decided to open this to the public and to our colleagues, and then we pick which answers have not been answered before and seem to be of most general interest,” Dr. Ohno-Machado explained.If this sounds like a straightforward approach, it’s not. Patient confidentiality laws make it hard for hospitals to share data and the information released by the CDC is limited.Maintaining patient confidentiality while sharing granular data is the most groundbreaking feature of the collaboration, called Reliable Response Data Discovery or known by its Star Wars-inspired acronym, R2D2.UCSD said R2D2 differs from other patient databases and registries because each health system maintains control of data rather than sharing it in a central repository. Through advanced computer techniques, each partner agency shares aggregated data, not patient-level information.The collaboration’s research is based on what’s called “observational data,” so Dr. Ohno-Machado said it’s not a replacement for a randomized, controlled clinical trial, which takes time. She noted their data reflects lessons on hospitalized patients, not everyone infected with the virus.But she said at a time when fast answers can save lives, COVID19questions.org could help. 3161

SAN DIEGO (KGTV) - Many of the 134 cats rescued from a Lakeside apartment are up for adoption in County animal shelters. Sheriff’s deputies who were conducting a welfare check at the apartment Thursday discovered the cats and called animal services.Most of the animals appear to be healthy and well-fed, though stand-offish at the moment.  RELATED: 'Dozens' of cats found inside Lakeside apartment during elderly neglect callThe adoptable animals are at the shelters in Bonita and Carlsbad.  All have been checked out by the veterinary staff and given flea and worm medicines.  Each will be spayed or neutered and chipped before adoption.  The adoption fee is per cat or kitten. 745

SAN DIEGO (KGTV) - Like Pfizer, Moderna, AstraZeneca, and many others, INOVIO Pharmaceuticals has also raced to develop a COVID-19 vaccine this year.“We’ve been working really hard to move our vaccine through the stages of clinical testing. Some things have taken a little bit longer than we hoped. I think that’s kind of always the case when you’re trying to go at great light speed,” said Dr. Kate Broderick, INOVIO Pharmaceuticals Senior VP of Research & Development based in San Diego.Broderick said with funding from the U.S. Department of Defense, the biotech company started its Phase 2 clinical trial evaluating its DNA vaccine candidate, INO-4800.The first U.S. participants received a dose of the experimental vaccine earlier this month. Approximately 400 adults in the U.S. are expected to be enrolled in the trial by the end of the month.“We hope that in the early part of 2021, we’ll be going into a really large Phase 3 trial where we’re asking the question does our vaccine protect against the disease itself,” she said.Broderick said the company hopes to enroll about 6,000 participants initially in its Phase 3 trial once they get the green light to begin.A press release from the company last week stated that “The Phase 3 segment of the INNOVATE remains on partial clinical hold until INOVIO satisfactorily resolves the FDA’s remaining questions related to the CELLECTRA 2000 device that will be used to deliver INO-4800 into the cells of the skin.”Earlier data released from Pfizer and Moderna’s studies showing high vaccine efficacy was positive news for INOVIO.“We feel that we’re in a really good place. There’s eight billion people on the planet, and we’re certainly going to need quite a few different types of vaccines to ensure everybody is protected,” she said. “The Moderna and Pfizer vaccines are RNA vaccines; ours is DNA vaccine”Broderick said one significant benefit of INOVIO’S DNA vaccine candidate is it doesn’t have to be stored in low-temperature freezers, making it easier to ship out worldwide if approved.“In fact, we can keep it at room temperature, sitting on a desk somewhere for a year with no impact,” she said.INOVIO is projecting to have 100 million doses of its vaccine ready in 2021.“With these vaccines being approved, there is definitely an end in sight, but don’t let your guard down too fast,” she said. “Unfortunately, until everyone in the country gets vaccinated, we will still have to adhere to those kinds of annoying things, wearing masks, socially distancing. I know it’s frustrating, especially before the holidays, but just keep yourself safe and the people you love safe.” 2648

SAN DIEGO (KGTV) — If there's one thing Californians know, it's that guacamole is always extra.Expect this weekend! National Chip and Dip Day comes on Saturday, but the fun starts Friday. Rubio's is giving away free chips and guacamole with any purchase on Friday and Saturday in celebration of the delicious event. Just present this coupon with any purchase and dip into some delicious freebies.At the very least, break open a bag at home and kick back with a handful of chips and side of dip. 502

SAN DIEGO (KGTV) - Local health care workers are seeing a massive number of at-risk patients through virtual visits amid concerns over COVID-19. “We've gone from having 100 visits a day [by phone or video] to 1,200 visits just yesterday alone, says Dr. Abi Olulade with San Diego's Sharp Rees-Stealy Group. She and hundreds of doctors with Sharp Healthcare are putting a special emphasis on telehealth appointments with patients who are considered at-risk because their immune systems can be weaker. RELATED: Coronavirus Impact: Concern over nurses' protective gear“[Patients] with lung disease, heart disease, diabetes and those that are immuno-compromised so we are focused on our higher risk patients,” she tells 10News.This week, 10News interviewed Dr. David Wetherhold at Scripps Health whose team is also trying to reach that same population through Scripps' telehealth program. It was supposed to roll out over the next 18 months, but with COVID-19, it's compressed into a few weeks. “The immuno-compromised, transplant patients, heart failure patients or cancer patients. [They’re] going to be our initial focus [with] trying to get them the care they need remotely without bringing them out into the community," Wetherhold said.RELATED: In-person EDD services temporarily closed“They are more at-risk of getting severe complications from coronavirus so we want to limit them coming into the office when we can,” adds Dr. Olulade. She wants to remind at-risk patients to stay in communication with their providers about any new symptoms, even if mild, that could warrant a need for further evaluation. If an office visit is required, she tells 10News that they'll prepare accordingly to receive those patients and limit any risks they could face. 1762