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SAN DIEGO (KGTV) – Locals seeking a career change may find the opportunity with several "recession-resistant" jobs in San Diego, as the region grapples with high unemployment amid the coronavirus pandemic.San Diego-Imperial Center of Excellence for Labor Market Research has identified 64 occupations ranging from entry-level to positions requiring a degree and include nursing, teaching, engineering, and technology industries among others. "I think people are going to want to also recession-proof their lives after having potentially been displaced from an industry," said Dr. Sunita Cooke, President of MiraCosta.Here's a look at the jobs, typical education needed, and earnings: 691

SAN DIEGO (KGTV) — In the race for a coronavirus vaccine, scientists often say we need more than one winner.That’s in part because different vaccines use different strategies to provoke the immune system, and each strategy has different strengths.Take the inactivated virus vaccine, an approach currently used in the vaccine against the poliovirus. In this approach, scientists take a live virus, kill it with chemicals or heat, and then introduce that viral corpse into a person.There are three groups in the final phase of human trials using inactivated coronavirus, primarily in China, according to a tracker from the Milken Institute.“The immune system can tell the difference between something that's a real threat and something that's not a threat, and so if you get injected with a dead virus your immune system has the tendency to not pay a lot of attention to that,” said Dr. Shane Crotty of the La Jolla Institute for Immunology.The downside of the inactivated virus approach is that it only elicits two out of the three of the parts of the immune system, Dr. Crotty said. It’s capable of producing antibodies and helper T-cells, but not killer T-cells.The modern take on the inactivated virus approach is called a viral vector vaccine.In this strategy, scientists combine elements of the coronavirus with a common cold virus called an adenovirus that won’t make you sick. Since the virus is alive, it can elicit all three kinds of immune responses, Dr. Crotty said.“There are no licensed vaccines right now that use that strategy, but there are all kinds of vaccine trials that have been done around the world with those types [of vaccines] showing that they're straightforward to manufacture. They're very safe,” he said.The University of Oxford is testing a viral vector vaccine for COVID-19 in a Phase 3 clinical trial.Then there are subunit vaccines. These include just a section -- or subunit -- of the virus’ protein.UC San Diego is working on a coronavirus candidate vaccine using this approach.There are subunit vaccines currently on the market for tetanus and other viruses.“Working with proteins is more challenging, just from a laboratory and manufacturing perspective,” Dr. Crotty said.Enter the next phase of vaccine development. Instead of using the virus itself or fragments of it, Inovio Pharmaceuticals is working on a vaccine strategy using just the virus’ genetic information.DNA-based vaccines simply introduce a genetically engineered blueprint of the virus into a person, and the cells do the rest.“Some people get confused about this. They think it’s a genetic vaccine that changes their DNA and becomes part of them, and that’s definitely not the case.” Dr. Crotty said. “They don’t become part of you. Your body chews them up.”Researchers have been working on DNA-based vaccines for about 20 years, Crotty said, but none are currently licensed for use.San Diego-based Arcturus Therapeutics is using an RNA-based approach, along with other companies like Pfizer and Moderna that have entered Phase 3 trials.Messenger RNA reads the DNA instructions and helps translate them into proteins.Dr. Crotty said the DNA and RNA approaches have similar drawbacks and benefits: they’ve never been approved for us, but both can be developed rapidly because they don’t require access to the physical virus.Around the world, there are more than 200 coronavirus vaccines currently in development, according to the Milken Institute. 3459

SAN DIEGO (KGTV) - Members of a newly formed Guardian Angels chapter in Pacific Beach went on patrol for the first time Saturday night.Members of the Sacramento Chapter traveled to San Diego to train the new volunteers. Administrator Sarah Bonesteel joined after a neighborhood crime walk, saying "crime is getting out of control, we've lost our parks, and our library and things like that."RELATED: Guardian Angels look to start street patrols in Pacific BeachThe Guardian Angels are a national crime prevention nonprofit organization that started in New York in 1979. The group said it created chapters in over 130 cities in 13 countries.While the group has several programs to prevent crime, the most visible are its street patrols. The Pacific Beach Chapter hopes to provide a safe environment after the bars close.Guardian Angels patrol in groups of at least two while wearing red berets and uniforms, and say the patrols are meant to serve as a visual deterrent and aim to avoid violent confrontations.Angels on patrols are unarmed but trained in self-defense to protect themselves in case a situation becomes physical. They hope they do not have to use their training.The organization conducts background checks on new members to ensure everyone's safety. 1270

SAN DIEGO (KGTV) — Locals and visitors in San Diego's mountains Friday awoke to a winter wonderland of snowfall.A Thanksgiving storm brought a fresh coating of snowfall to the county's higher elevations, including areas of Julian, Descanso, Palomar Mountain, Pine Valley, and Mt. Laguna. A winter storm warning will continue through 10 p.m. Friday.San Diego mountains can expect to see about 10 to 18 inches of snow above 5,500', 10News meteorologist Megan Parry reports. Areas between 3,000 and 4,000 feet will see trace amounts to 2 inches of snow, and areas 4,000 and 4,500' can expect about 3 to 8 inches. The county's highest peaks could get 2 feet of snow by the end of the day.RELATED: Snow in San Diego! Here's what you'll need and where to go for snowChains are required when heading up to the mountain areas and wind gusts up to 50 mph will make traveling hazardous. Icy roads is also a concern.Not heading to the snow this weekend? Check out the snowfall in Julian Friday morning from the comfort of your screen:Scattered showers will continue to keep most of San Diego soaked Friday, but the worst of the rain has moved out of the county. Thanksgiving Day saw about 1.37" of rain locally, breaking the San Diego's previous Thanksgiving record of 1.26" set in 2008.Several crashes were recorded throughout the day Thursday. Travel on rain slicked roads is also a concern early Friday.RELATED: Coast-to-coast storm will dump more rain and snow during weekend travel rushThunderstorms are possible throughout areas of San Diego's East County and periods of heavy rain could last through the morning.A beach hazard statement is in effect until 4 p.m., with waves of about 2 to 7 feet and strong rip currents a possibility. The threat of flooding locally also continues into Friday, the biggest threat being between 8 a.m. and 10 a.m.Locals are advised to avoid going into the water along the coast, as storm runoff could bring contaminants to San Diego's beaches. 1979

SAN DIEGO (KGTV) — In the late '80s Gary Cheatham founded Auntie Helen's in a one-car garage in North Park in 1988.Gary did fluff-and-fold laundry first for one, then for a handful of friends who were sick with AIDS."Everybody could do it. But nobody would do it. And I think that makes him a superhero in my eyes," says Auntie Helen's current Executive Director, Rod Legg.Fear and stigma at the time hurt the LGBT community as much as the disease, but word spread quickly about Gary's services, and Auntie Helen's grew. Sadly, so did the disease.HIV and AIDS claimed more than 100,000 lives in the U.S. in the 1980s. Many of Gary's clients and friends who died willed their estates to Auntie Helen's.Their belongings accumulated in Gary's garage, which was also where he did laundry. Eventually, with help from a few high-powered friends and other activists, Gary opened Auntie Helen's thrift store in 1989.The laundry service and the thrift store are still located in North Park."We also do COVID-19 [laundry], which is our frontline medical workers. That's a tie in to the past, we had to do that. We had to offer that," Legg says.They're expanding the store, and their outreach, giving out free groceries to their regular clients (about 25-35 individuals) and now also to frontline workers.With COVID-19 leaving so many more people on hard times, they started delivering groceries — no questions asked, no referral needed. At one point, to more than 300 people.Legg explains, "this is everybody's HIV in a sense... We don't know where we're at. We're all wondering what's going to happen the next day, but most importantly is neighbor to neighbor we need to make sure we're taking care of each other."All in keeping with the legacy of Gary Cheatham, about whom, Legg says, "this man was way before his time... Can you imagine the faces of the people that got the hugs, and the clothes? We should all be our heroes, for each other." 1943