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Scientists at the University of Nevada, Reno School of Medicine (UNR Med), led by its Nevada State Public Health Laboratory (NSPHL) are studying a likely case of COVID-19 reinfection.Forty-eight days after testing positive for SARS-CoV-2 in April 2020 and after testing negative consecutively twice, a Washoe County, Nevada patient tested positive again, in June.The patient had tested negative on two separate occasions in the interim. The genomes of the patient’s virus samples were sequenced in April and June, displaying significant genetic discordance between the two cases, implying the patient was infected twice.“We examined the genomic material of the viruses and samples to investigate this, says NSPHL Director Mark Pandori. “It is just one finding, but it shows that a person can possibly become infected with SARS-CoV-2 a second time.”To solidify confidence in the case, Pandori and the research team partnered with the Washoe County Sheriff’s Office Biology Unit to conduct identity testing on the specimens and lab samples evaluated in the study to verify the specimens were from the same person.Embedded in the genomic material of SARS-CoV-2 is a detailed code that Pandori says may provide insight to a better understanding of this virus.“A virus has a biological genome like all living things. Since March, the NSPHL has analyzed the genomic RNA of approximately 200 positive COVID-19 samples from Nevadans who have tested positive for COVID-19,” said Pandori. “The power of genomic information could turn the tables in the fight against the coronavirus.” The information is shared to a world-wide database known as “GISAID”,” alongside the work of thousands of researchers.According to Pandori and the NSPHL-led research team, reinfection cases are a potential warning sign that it is possible to catch COVID-19 more than once, and with unpredictable severity.“If reinfection is possible on such a short timeline, there may be implications for the efficacy of vaccines developed to fight the disease. It may also have implications for herd immunity,” says Pandori. “It is important to note, that this is a singular finding. It does not provide any information to us with regard to the generalizability of this phenomenon.”Herd immunity depends on the theory that after natural infection, our immune systems will collectively protect us as a community from reinfection and further spread. There are currently many more unknowns than knowns about immune responses to COVID-19. “After one recover from COVID-19, we still do not know how much immunity is built up, how long it may last, or how well antibodies play a role in protection against reinfection,” says Pandori.”While research and scientific advancements continue to build, Pandori says the hard work of fighting this pandemic together will continue through the use of facial coverings, hand-washing, social distancing, as well as wide-scale testing, contact tracing, and isolation of new cases.“This is a novel disease. We still have a steep learning curve ahead and lots of work to do, especially as inconvenient truths arise,” says Pandori.The NSPHL team are publishing their COVID-19 reinfection findings. Their report is publicly accessible on the SSRN preprint server, at https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3681489. This story was first reported by KTNV in Las Vegas, Nevada. 3384

SANTA ANA, Calif. (CNS) -- The Golden State Killer went before a judge Monday to admit his guilt in a string of murders, rapes and other crimes in the 1970s and 1980s, stretching from Sacramento County to Orange County, after reaching a plea deal to avoid the death penalty.Joseph James DeAngelo Jr., 74, Monday morning began the process of admitting guilt in 13 murders, including four in Orange County, in a hearing before a Sacramento judge that was livestreamed on YouTube. By the noon lunch break, he was about halfway through entering his pleas, speaking in a raspy, trembling voice just above a whisper.Orange County District Attorney Todd Spitzer was in Sacramento to take the plea for the Orange County cases Monday afternoon.Under the plea deal, the onetime Exeter and Auburn police officer is expected to be sentenced to at least 11 consecutive terms of life in prison without the possibility of parole and 15 concurrent life sentences.Various prosecutors from across the state began the process of reading detailed descriptions of the defendant's crimes, starting with the murder of 45-year-old Claude Snelling on Sept. 11, 1975, in Visalia. DeAngelo shot and killed Snelling as he attempted to rescue his daughter, who the killer was trying to kidnap.DeAngelo also pleaded guilty to attempting to kill Detective William McGowen on Dec. 10, 1975, as the then-Visalia officer attempted to arrest him for a series of burglaries attributed to the "Visalia Ransacker" from April 1974 through December 1975.DeAngelo pleaded guilty to the beating deaths of Goleta residents Debra Manning, 35, and Robert Offerman, 44, on Dec. 30, 1979, in their home in Santa Barbara County, and the beating deaths of Gregory Sanchez, 27, and Cheri Domingo, 35, both of Goleta, on July 27, 1981. DeAngelo also raped Manning and Domingo.DeAngelo also pleaded guilty to bludgeoning to death Charlene and Lyman Smith, both of Ventura, with a fireplace log on March 13, 1980. Lyman Smith, a 43-year-old former deputy district attorney, and his 33-year-old wife were found dead by his 12-year-old son. The killer also raped Charlene Smith and stole some of her jewelry, prosecutors said.Ron Harrington, the son of Dana Point residents Keith and Patrice Harrington, who were slain on Aug. 21, 1980, said he and his family still support the death penalty for DeAngelo, but believe the plea deal is the best former of justice they could get."This is the most amount of justice and most amount of closure we could ever obtain," Harrington told City News Service. "This guy is absolutely the worst of the worst... He is truly the poster child for the death penalty."But given the age of witnesses and investigators as well as the COVID- 19 pandemic, it made the logistics of scheduling of even a preliminary hearing difficult to accomplish, Harrington said. Also, Harrington noted, Gov. Gavin Newsom has put a moratorium on the death penalty in the state."The preliminary hearing in this case had 100 witnesses and the preliminary hearing was going to last literally months," Harrington said. "And beyond that issue we're also dealing with COVID-19. And how do you protect all these remaining victims and witnesses in the era of the coronavirus?"Harrington said it was a "totally surreal experience" hearing DeAngelo admit his crimes.DeAngelo is expected to be ordered back to court in August, when victim impact statements will begin.Prosecutors on the case announced in April 2019 they would seek the death penalty for the Citrus Heights resident, who is charged with 13 murders.Multiple issues cropped up in the case, with many witnesses dying, a source told CNS."Some key witnesses are 80 years old or above," the source said, adding that includes many detectives who worked on the killings.Support in recent weeks among the families of the victims has been "overwhelming" for a plea deal, the source said.In Orange County, DeAngelo is accused of killing 24-year-old Keith and 28-year-old Patrice Harrington on Aug. 19, 1980, in Dana Point; 28-year-old Manuela Witthuhn in Irvine in February 1981; and 18-year-old Janelle Cruz in Irvine in May 1986.The Harringtons, who lived in a single-story home in the gated Niguel Shores community, were attacked in their bedroom, said Investigator Larry Pool of the Golden State Killer task force. Their bodies were found on their blood- spattered bed with ligature marks on their wrists and Patrice's ankles, Pool wrote in a probable cause declaration.Their killer left the binds on the bed. It appears he tied their hands behind their backs, covered them in a comforter and slammed a blunt object over their heads, Pool said.Investigators in 1996 matched semen at the crime scene to the killer in the two other Orange County cases, Pool said. The identity of the killer remained unknown until 2018, when investigators used a public genealogy database with DNA recovered from an item discarded by DeAngelo, former Orange County District Attorney Tony Rackauckas previously said.Witthuhn was attacked sometime between 11 p.m. on Feb. 5, 1981, and 2 a.m. on Feb. 6, 1981, when investigators believe she died, Pool said. The cause of death was skull fractures from a beating, Pool said, adding that her parents discovered her body in a sleeping bag when they went to check on her. There was no evidence of a struggle and she had ligature marks on her wrists and on her right ankle.Cruz was killed about 5 p.m. on May 5, 1986, in her bed in her Irvine home. Blood covered her head and neck and she was partially covered by her blanket, Pool said. She had hemorrhaging in her eyes and bruises on the bridge of her nose, according to Pool, who said the killer knocked out three of her teeth -- with two found in her hair.She had no ligature marks on her wrists like the other victims, but there were abrasions, leading investigators to speculate her killer squeezed her wrists so hard he left a mark, Pool said. Her lower lip was swollen, her tongue bitten. An ultraviolet light spotlighted semen on the victim, according to Pool. No murder weapon was found, but a pipe wrench in the backyard was missing.The cause of death was "crushing skull fractures," he said.DeAngelo is also charged with killing Brian and Katie Maggiore in Rancho Cordova on Feb. 2, 1978, and is alleged to be the East Area Rapist responsible for 52 attacks in Contra Costa, Sacramento and Santa Clara counties from June 1976 through July 1979, Pool said. 6453

Say goodbye to another 40 Sears and Kmart stores.Sears Holdings (SHLD), the bankrupt parent company of the two retailers, said Thursday that 11 Kmart locations and 29 Sears stores will close their doors in February 2019 — adding to the nearly 200?locations the company has already said will shut down in coming months.The closures are part of Sears Holdings' efforts to drastically reduce costs and find a viable way forward as it moves through bankruptcy proceedings. The company has?been struggling for several years and is drowning in debt.Liquidation sales at the 40 locations "are expected to begin late next week," the company said.Sears Holdings operated about 1,000 stores as recently as February but has been shuttering underperforming stores. When the company filed for bankruptcy last month, it said it only had about 400 stores that could turn a profit. Now, it's in the process of shedding more dead weight.In its bankruptcy filing, Sears named 142 of its worst-performing stores that would shut down in the coming months. That was in addition to 46 stories already pegged for closure.The company will have less than 500 Sears and Kmart stores left open after the additional closures.Here's the list of the 40 stores Sears announced would close Thursday, by state or US territory:ArkansasSears: Airport Way, FairbanksArizonaSears: 4604 E Cactus Road, PhoenixCaliforniaKmart: 26471 Ynez Road, TemeculaSears: La Cumbre Plz, Santa BarbaraConnecticutSears: 470 Lewis Ave, MeridenFloridaSears: 801 N Congress Ave, Boynton Beach FLSears: 3342 Nw Federal Hwy Us#1, Jensen BeachIllinoisKmart: 3443 W Addison, ChicagoKmart: 3250 Clear Lake Road, SpringfieldIdahoSears: 2300 E 17Th St, Idaho FallsIndianaSears: Marquette Mall, Michigan CityMaineKmart: 18 Elm Plaza, WatervilleMarylandSears: 7103 Democracy Blvd., BethesdaMichiganSears: 5575 B Drive N, Battle CreekMississippiSears: 1740 Bonita Lakes Circle, MeridianSears: 1001 Barnes Crossing Road, TupeloNebraskaSears: 3404 W 13Th St, Grand IslandNew YorkKmart: 805 New York Ave, HuntingtonSears: 3065 Route 50, Saratoga SpringsSears: 21182 Salmon Run Mall, WatertownNevadaSears: 4355 Grand Canyon Dr Las VegasNorth CarolinaSears: 3320 Silas Creek Pkwy Winston SalemOhioSears: 987 E Ash St, PiquaPennsylvaniaKmart: 7101 Roosevelt Blvd, PhiladelphiaKmart: 1901 Lincoln Hwy, North VersaillesSears: 1665 State Hill Road Reading, WyomissingSears: 344 Stroud Mall, StroudsburgPuerto RicoKmart: Castro Perez Ave (Pr 122), San GermanKmart: 100 Ave. San, Patricio Guaynabo / San JuanKmart: Betamces 400, Las Catalinas Mall, CaguasSouth CarolinaSears: 2197 Dave Lyle Blvd, Rock HillTennesseeSears: Southland Mall, MemphisSears: 401 Northgate Mall, ChattanoogaSears: 198 Foothills Mall, MaryvilleSears: 1720 Old Fort Pkwy, MurfreesboroTexasSears: 750 Sunland Park Dr, El PasoSears: Longview Texas Mall, LongviewVirginiaSears: 10101 Brook Road, Glen Allen / RichmondWisconsinSears: 2500 Milton Ave, JanesvilleKmart: 6077 S Packard Avenue, Cudahy 3027

School nurses already have a lot of responsibilities, but the possibility of students being back in classrooms this fall may add a new duty: screening for COVID-19."There seem to be no certainties. The guidance changes frequently and there is some concern that the guidance doesn’t take into account the realities in a school building," says Laurie Combe, the President of the National Association of School Nurses.Combe says the pressure will be on school nurses to help screen and isolate any students or staff who could be showing symptoms of COVID-19. But not all schools across the country have the ability to do this."We're supposed to isolate those students or staff members and does a school have the space or capacity to do that?" says Combe.According to the Department of Education, there are 98,000 public schools in the United States. The National Association of School Nurses’ research has shown 25% of those schools have no access to a school nurse."Not part-time, not one nurse covering multiple schools, just no school nurse," says Combe.“COVID has revealed to us is that schools are relying heavily on school nurse expertise to guide their procedures and policies moving forward into reopening,” Combe added. “So what do those schools that don’t have a school nurse do?"Visalia Unified School District in California has about 32,000 students. The district's 12 credentialed school nurses help lead an additional 36 nurses in meeting students' health needs."Our health department reached out and identified the 12 school nurses as emergency disaster workers so instead of enjoying a summer vacation, the nurses are working at the health department and helping to monitor COVID," says the district's Director of Health Services Suzie Skadan. Skadan says that extra experience will be helpful when school is back in session."They will have this additional experience and hands-on happening so they will know what to do when we come back," says Skadan.Visalia unified is working closely with their local health department to put every CDC-recommended protocol in place come the fall."It is an added burden for the school nurse but it's very necessary to keep our students safe. So we think planning ahead and having systems in place will make the best of this situation," says Skadan. Both the National Association of School Nurses and Visalia Unified say ideally there'd be more nurses on hand this fall."Unfortunately, we're having big budget cuts. It's been a bad budget year and then we have COVID on top of that so we are not hiring additional nursing staff. We schedule people around to make things work so hopefully we can manage it this way," says Skadan.While not every school will have the ability to test students for COVID this next school year, the National Association for School Nurses expects more students will be tested. Combe refers to a recent conversation she had with a teacher."I said, ‘So what are you going to do if a child in your classroom starts coughing?’ Normally you would send that child to get some water or you know help them manage that. She said, ‘I’m sending that child to the school nurse,'" says Combe.Combe says nurses focus much of their time on health education for students, faculty and their entire school community, a role that will be amplified come next school year. 3334

SANTA BARBARA, Calif. (AP) — The search for the final victim of a boat fire off the Southern California coast has been suspended until early next week because of gusty winds and rough seas.Authorities said they also suspended efforts to salvage the Conception off of Santa Cruz Island because the conditions were expected to last through the weekend.Santa Barbara County Sheriff's Lt. Erik Raney says the Conception has been secured underwater, where it will remain until it is safe to resume the salvage operation.RELATED: Owners of Conception seek to head off lawsuits after 34 die in boat fire off Santa Cruz IslandInvestigators eye possible causes of Conception boat fire off Santa BarbaraThirty-four scuba divers died when the boat caught fire and sank before dawn on Monday. They were sleeping in a cramped bunkroom below the main deck and their escape routes were blocked by fire.Medical examiners say the victims appear to have died from smoke inhalation. 971

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