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LA JOLLA (KGTV): Researchers at the UC San Diego Moores Cancer Center and the La Jolla Institute of Allergy and Immunology have teamed up to find a new way to fight cancer.They've created a vaccine that can help teach the immune system how to attack only cancer cells and leave the rest of the body alone."Patients will be able to tolerate their therapy much better than they have so far on conventional approaches," says Dr. Stephen Schoenberger from the La Jolla Institute.Each vaccine is highly personalized to the patient. According to a release from UC San Diego, the vaccines "defines the neoantigens – foreign protein fragments recognized by the immune system – in a patient’s cancer. With neoantigens identified, the team can identify peptides – strings of amino acids – that can be used to create a vaccine to stimulate a protective immune system response."Simply put, the new vaccine takes information from a patient's immune system and the tumor and uses it to help white blood cells to fight it."We're giving them life and giving them hope," says Dr. Schoenberger.The first patient in the clinical trial is Tamara Strauss. She was diagnosed with pancreatic cancer in 2015 and went through chemotherapy and surgery."It was brutal," says Strauss. "It's been three and a half years of hell."Strauss' parents helped fund the clinical trial with a million donation. She says she feels fortunate they could do that, but also hopeful that it helps others down the road."I really pray that this vaccine and personalized form of treatment really does change the paradigm of cancer treatment," says Strauss.During the trial, ten patients will get three doses of the vaccine. They'll also be on Keytruda, an immune system boosting drug for up to two years. Their health will be monitored for five years to determine the vaccine's effectiveness. 1871
L.L. Bean became the latest retailer to announce that it will no longer sell guns or ammunition to customers younger than 21.In response to a tweet from one consumer asking the outdoors retailer to change its policy, the Maine-based retailer replied late Thursday, "In the wake of this shooting we have reviewed our policy on firearm sales, and we will no longer be selling guns or ammunition to anyone under the age of 21."It's the fourth high-profile retailer to change its policy on gun sales to younger customers in the wake of the Parkland, Florida, high school shooting last month.On Wednesday Dick's Sporting Goods, the nation's largest sporting goods retailer, and Walmart, the nation's largest retailer, announced new their restrictions. Dick's also said it would no longer sell assault-style rilfes to anyone at its stores. Kroger, the nation's largest grocer, announced Thursday it would raise the age for weapon purchases at its Fred Meyer general merchandise stores. 999

Jakelin Caal Maquin died less than 48 hours after Border Patrol agents detained her and other migrants at a remote New Mexico border crossing.The 7-year-old girl had traveled with her father more than 2,000 miles from her indigenous community in northern Guatemala and celebrated her birthday on the road, hoping to make it to the United States safely.Here is a rundown of the last hours before Jakelin's death on December 8, as told by the Department of Homeland Security. All times are local. 502
JULIAN, Calif. (CNS) - A 63-year-old man died after crashing his pickup into a tree at an RV park near Julian, authorities said Wednesday.The crash happened about 6:40 p.m. Tuesday on KQ Ranch Road in the KQ Ranch RV resort, off state Route 79, California Highway Patrol Officer Travis Garrow said.The victim was driving a 2013 Ford F-150 pickup eastbound when, for unknown reasons, he drove off the north side of the road and slammed into a tree, Garrow said.Witnesses attempted to help the driver until medics arrived, but the man was pronounced dead before he could be airlifted to a hospital, the officer said.The driver's name was withheld pending family notification.Investigators determined that alcohol and/or drugs were suspected factors in the crash and the man was not wearing a seatbelt, Garrow said. 820
JACKSONVILLE, Fla. – Like its namesake, President Andrew Jackson, Jacksonville is a city where race plays a prominent role in its history.“We do have our issues,” said Isaiah Rumlin, president of the Jacksonville chapter of the NAACP.He said the city has known its share of unrest, dating back to the civil rights movement of the 1960s. He’s also concerned the same could happen during the Republican National Convention in August.“We know we're going to have some problems here and there's going to be some demonstration taking place,” Rumlin said.The head of the county’s GOP hopes that’s not the case.“It’s only divisive, if you choose to make it so,” said Dean Black, chairman of the Duval County, Florida Republican Party.President Trump is scheduled to give his renomination speech on August 27, 60 years to the day of a violent episode in Jacksonville’s civil rights movement.It’s known as Ax Handle Saturday.“It was just a bloody day in the city of Jacksonville,” Rumlin said. “And it will be a day that we will never forget.”What happened next is a disturbing part of Jacksonville’s history. On that August day in 1960, a group of about 200 white men – brandishing baseball bats and ax handles – attacked a group of African American protesters at a lunch counter sit-in. The violence eventually spread into a park and nearby streets, where the mob attacked any African Americans in sight.“It didn’t make any difference who you were. If you had black skin, you were attacked,” said Rodney Hurst, Sr., who survived Ax Handle Saturday.Hurst was a teenager then, participating in a lunch counter sit-in, when the violence began.“Our only option then was to run for safety because there was nothing,” he said. “There were no policemen downtown for protection of any kind, so we started running.”He later wrote a book about his experience, called “It Was Never About a Hot Dog and a Coke.”“The title, ‘It Was Never About a Hot Dog and a Coke,’ simply means that it was about human dignity and respect,” he said.A 60th anniversary commemoration of Ax Handle Saturday has long been planned in the downtown park where it took place. Organizers said the RNC being in town at the same time won’t change that.“The Republican Party has connected Donald Trump’s acceptance speech in an inextricable way to the anniversary of Ax Handle Saturday,” Hurst said. “We don’t mind. If you want to do something on August 27, that’s fine. What we’re commemorating happened 60 years ago.”It’s an incident that, despite the passage of time, remains very much in the present.Just last week, the city of Jacksonville removed a Confederate monument from the public park where violence occurred on Ax Handle Saturday in 1960. The school district there is also now looking at whether schools named after confederate leaders will be renamed. 2826
来源:资阳报