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The U.S. will pay drug company Pfizer .95 billion to produce and deliver 100 million doses of the company's COVID-19 vaccine candidate should the drug prove effective in human trials the company said in a press release on Wednesday.Pfizer will deliver the vaccine if and when the drug receives Emergency Use Authorization from the FDA after a large-scale Phase 3 trial.According to the reports, the deal includes an option for the government to purchase an additional 500 million doses of the vaccine.“Expanding Operation Warp Speed’s diverse portfolio by adding a vaccine from Pfizer and BioNTech increases the odds that we will have a safe, effective vaccine as soon as the end of this year,” Health and Human Services Sec. Alex Azar said in a statement. “Depending on success in clinical trials, today’s agreement will enable the delivery of approximately 100 million doses of this vaccine to the American people.”Pfizer and German firm BioNTech are working together to develop the vaccine.On Monday, Pfizer said in a press release that results from Phases 1 and 2 of a German trial indicated that the drug "could potentially be administered safely, with a manageable tolerability profile," according to data from the tests.Biotech company Moderna is also working to develop a coronavirus vaccine. That candidate will move into Phase 3 testing by the end of the month, and the government has also agreed to purchase and distribute the drug should the large-scale test prove effective. 1497

The toy run in December is usually one of the big ways Children's Hospital Colorado gets donated toys. But because of COVID-19, the supply of toys is down considerably. So the hospital reached out to some riders, and Sunday, they got a special delivery to help replenish that supply.Kids at Children's Hospital know when they hear those Harley engines roar, toys are on the way."Any motorcycles coming up to the hospital, the kids plaster themselves the windows. They love to see the bikes riding up," volunteer Bob Cuculich said."That's why we do it. It's things like this that make it all worthwhile," organizer Eddie Dane said.But it's not December when this toy run usually happens."Because of COVID this year, the hospital reached out to Rocky Mountain Harley Davidson, because we're a sponsor to the toy run and have been for years," Dane said.Dozens of bikers answered the last minute call to help."They're not reusing toys. So we are are going to replenish their supply and do the best we can to get them some more toys to last them until December," Dane said.They didn't know how many bikers would show. They just knew they needed to try to help the kids."There's a huge need," Cuculich said.But the roars were there, filling up the bins, and they hope more toys can be brought. Just no stuffed animals right now."Plush toys right now, they are just too hard to keep clean, and infection control just makes it a challenge to be able to give those to the kids," Cuculich added.The bikers hope this special delivery makes the kids happy and lasts until the main ride in December. Just a little Christmas in July.KMGH's Sean Towle first reported this story. 1671

The wild is calling, and we're answering. Reserve yours 7.13.20. #FordBronco pic.twitter.com/2LEDH5FNtr— Ford Motor Company (@Ford) June 29, 2020 153

The U.S. has surpassed another bleak marker in the COVID-19 pandemic, as the country has reached 10 million confirmed cases of the virus, according to a database kept by Johns Hopkins.The milestone comes just hours after global cases surpassed 50 million, meaning about one out of every five people around the world diagnosed with the virus since the pandemic began has been diagnosed in the U.S.At least 237,000 Americans have died of the virus since the pandemic began. The U.S. continues to lead the world in both total cases and in deaths linked to the virus.The U.S. surpassed its 10 millionth case as the country deals with a disturbing spike in infections ahead of the winter months. The country surpassed 120,000 new cases in a single day three times last week, obliterating previous records. Prior to last week, the most confirmed cases the U.S. had seen in a single day was 102,000.The U.S. has recorded a million new cases of COVID-19 in the last 10 days alone. The country surpassed the 9 million case plateau on Oct. 30.In addition to the spike in cases, hospital resource use is also on the rise, and deaths linked to the virus are up slightly in recent days, though the death rate is not near what it was in March and April. Johns HopkinsHealth experts have warned that the U.S. is currently in a perilous position in the pandemic, with transmission rates as high as they have ever been as Americans move social gatherings indoors for winter months.In a memo last week, Dr. Deborah Birx — a member of the White House coronavirus task force — warned that the country is entering "the most deadly and concerning" phase of the pandemic.Late last month, Dr. Anthony Fauci — a member of the White House coronavirus task force and the county's top expert on infectious diseases — warned that the U.S. was in for a "whole lot of pain" if things didn't change soon.The U.S. did get some good news in the pandemic on Monday, as Pfizer announced that its vaccine candidate has been 90% effective in promoting immunity against the virus. However, even if the vaccine were to get FDA approval in the next few days, it would still take several months for most of the country to be vaccinated — and officials fear that vaccine skepticism could keep immunity levels below the threshold to stifle the virus. 2314

The red carpet, the stars, the fashion, the acceptance speeches.It's all going down at the 90th Academy Awards.Here's what you need to know about the ceremony:Who's hosting the Academy Awards?Late-night host Jimmy Kimmel will (hopefully) bring the funny again, just as he did at last year's ceremony.Given his more politically-charged monologues recently on "Jimmy Kimmel Live," there are sure to be some Trump jokes -- and disses.Related: Jimmy Kimmel brings new political profile to Oscar-host roleWhat's different about the Oscars this year?The action kicks off a half hour earlier this year, starting at 8 p.m. EST/5 p.m. PST on ABC.Viewers will just have to wait and see if that extra time will translate into longer speeches by the winners.What will people be talking about on the Oscars red carpet?That could be tricky this year because E! host Ryan Seacrest is set to have his usual red carpet hosting duties.Seacrest has been defending himself against an allegation of sexual misconduct. Though Seacrest was cleared of any wrongdoing by the network after a third-party investigation, strong support for the #MeToo movement and the Time's Up campaign might make for some awkward encounters.Related: Ryan Seacrest's Oscar night could prove complicatedWho's presenting the Oscars?The list is pretty impressive and includes Sandra Bullock, Emily Blunt, Dave Chappelle, Jodie Foster, Eiza González, Nicole Kidman, Matthew McConaughey and Christopher Walken, among others.Oscar-winner Lupita N'yongo, one of the stars of what is arguably the biggest film currently in theaters, "Black Panther," will also present.Who will win the Oscars?That is the question of the evening.While there are some frontrunners in the acting categories, the best picture Oscar is up for grabs.Related: Oscar nominations 2018 - The full listOne thing we do know is that safeguards have now been put in place to ensure there won't be another envelope mix-up."La La Land" was mistakenly named best picture last year, when the winner was in fact "Moonlight."Related: Remembering the 'Moonlight' and 'La La Land' Oscars fiascoWhere to watch the Academy Awards?ABC will begin its live coverage of the red carpet at 6:30 p.m. EST, available on broadcast platforms and live-streaming on ABC.com or the ABC app.The-CNN-Wire? & ? 2018 Cable News Network, Inc., a Time Warner Company. All rights reserved. 2388