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The U.S. will pay more than billion for 100 million doses of a potential Covid-19 vaccine manufactured by Johnson & Johnson.The deal is one of several large agreements between the government and pharmaceutical companies as part of Operation Warp Speed, aimed at creating, testing, manufacturing and distributing a Covid-19 vaccine quickly.The Trump administration’s deal with Johnson & Johnson, announced Wednesday, allows for the purchase of an additional 200 million doses.Johnson & Johnson’s vaccine, developed by subsidiary Janssen Pharmaceutical Companies, has shown positive preclinical results. Testing of their vaccine is currently underway with human trials in the United States and Belgium.The Johnson & Johnson vaccine testing is reportedly behind some of the more advanced-stage potential vaccines, like those from Moderna, Pfizer and AstraZeneca, which have begun phase three human trials.“We greatly appreciate the U.S. government’s confidence in, and support for, our R&D platform and efforts and the scalability of our vaccine technology. We are scaling up production in the U.S. and worldwide to deliver a SARS-CoV-2 vaccine for emergency use,” said Paul Stoffels, M.D., Vice Chairman of the Executive Committee and Chief Scientific Officer, Johnson & Johnson in a statement.The company says they are committed to global access to the vaccine following approvals, and has a goal of supplying 1 billion doses globally through the end of 2021. 1493

The White House has once again lowered the American flag to half-staff, after the flag was left at its full height for most of the day on Monday.In a statement released at about 4 p.m. ET, President Trump ordered flags be flown at half-staff until Sunday, the day of McCain's internment at the U.S. Naval Academy in Annapolis. The Trump administration faced criticism from politicians across party lines for choosing to fly the flag at full-staff while the rest of the federal government continued to honor Senator John McCain by keeping the flag low. Ohio Gov. John Kasich called the decision to keep the flags flying high "shameful."While protocol calls for the flag to be flown at half-staff the day and the day after a member of Congress dies, recent tradition has kept the flag at half-staff until sunset on the day of member's interment.   868

The Yale University police officers who were called to investigate a napping black graduate student ultimately admonished the white student who had contacted police in the first place, a Yale vice president says.The incident, captured in two Facebook Live videos, has sparked outrage about racial profiling and policing.Kimberly Goff-Crews, Yale's vice president for Student Life, said in an email to students Wednesday night that she's been "deeply troubled" by the incident.Officers interrogated Lolade Siyonbola, a black graduate student at Yale, early Tuesday after a white student found her sleeping in a common room of their dorm and called police.Siyonbola had been working on a paper in the Hall of Graduate Studies and fell asleep. Another student came in, turned on the lights and told her, "You're not supposed to be sleeping here. I'm going to call the police."Two police officers arrived and began questioning Siyonbola in a stairwell. When she asked them about the complaint, one officer said, "She called us (and) said there's somebody who appeared they weren't ... where they were supposed to be."The officers asked for her ID, and after some delay in verifying the spelling of her name, she was cleared to go.In the aftermath, Yale officials have defended the police response to the situation."We believe the Yale police who responded followed procedures," said Yale spokeswoman Karen Peart. "It is protocol in such circumstances for the police to ask for student (or staff) identification cards. Both students had to identify themselves."CNN has reached out to the other student for comment.The delay with verifying Siyonbola's ID was because the name on her card was her preferred name, which did not exactly match her name in university records, Peart said."As we do with every incident, we will be reviewing the call and the r

The US Food and Drug Administration approved two cancer treatments, Vitrakvi and Xospata, this week after expedited reviews.Vitrakvi, approved Monday, is "a treatment for adult and pediatric patients whose cancers have a specific genetic feature (biomarker)."The FDA said in a statement that it is the second approved cancer treatment that is based on a tumor biomarker instead of the place in the body where the tumor originated.Vitrakvi will be used for the treatment of solid tumors that have an NTRK (neurotrophic receptor tyrosine kinase) gene fusion that do not have a known resistance mutation, that are not metastatic or where surgical removal is likely to lead to severe morbidity, and that have no alternative treatments or have progressed after treatments.NTRK genes are rare but occur in many types of cancer, the FDA said, such as mammary analogue secretory carcinoma and infantile fibrosarcoma.Xospata tablets, approved Wednesday, are for the "treatment of adult patients who have relapsed or refractory acute myeloid leukemia (AML) with a FLT3 mutation," according to the FDA.Alongside the tablets, the agency also approved a diagnostic to detect the mutation."Approximately 25 to 30 percent of patients with AML have a mutation in the FLT3 gene. These mutations are associated with a particularly aggressive form of the disease and a higher risk of relapse," Dr. Richard Pazdur, director of the FDA's Oncology Center of Excellence, said in the statement.AML is a rapidly progressing cancer that affects the numbers of normal blood cells and calls for continuous transfusions, the FDA said.Both treatments were granted Priority Review designation.Priority Review, established in 1992, means the FDA aims to review the drug or treatment within six months, opposed to 10 months for a standard review."A Priority Review designation will direct overall attention and resources to the evaluation of applications for drugs that, if approved, would be significant improvements in the safety or effectiveness of the treatment, diagnosis, or prevention of serious conditions when compared to standard applications," the FDA says.Both treatments also received?orphan drug?designation, a status granted to drugs for rare diseases or conditions. 2261

The Trump administration has finalized a regulation that overturns Obama-era protections for transgender people against sex discrimination in health care. Friday's action is certain to be challenged in court by LGBTQ groups and others.The policy shift, long-sought by the president’s religious and socially conservative supporters, defines gender as a person’s biological sex. The Obama regulation defined gender as a person’s internal sense of being male, female, neither, or a combination.The Trump administration said that the new rules come with a .9 billion budget reduction over the course of five years. The costs are associated with enforcement efforts. “HHS respects the dignity of every human being, and as we have shown in our response to the pandemic, we vigorously protect and enforce the civil rights of all to the fullest extent permitted by our laws as passed by Congress. We are unwavering in our commitment to enforcing civil rights in healthcare,” Roger Severino, Director of the Office for Civil Rights at HHS.The Human Rights Campaign already announced it will sue the Trump Administration to stop the move.“We cannot and will not allow Donald Trump to continue attacking us. Today, the Human Rights Campaign is announcing plans to sue the Trump administration for exceeding their legal authority and attempting to remove basic health care protections from vulnerable communities including LGBTQ people. And, to add insult to injury, the administration finalized this rule on the anniversary of the Pulse shooting, where a gunman killed 49 people in an LGBTQ nightclub,” said HRC President Alphonso David. “LGBTQ people get sick. LGBTQ people need health care. LGBTQ people should not live in fear that they cannot get the care they need simply because of who they are. It is clear that this administration does not believe that LGBTQ people, or other marginalized communities, deserve equality under the law. 1940