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SAN DIEGO (KGTV) - Anyone touched by Alzheimer's knows how painful the disease is. "It's affected my family. It's affected most families. It's such a prevalent disease. As people get older, it becomes quite likely this will become an issue," said Paul Aisen, director of USC's Alzheimer's Therapeutic Research Clinic (ACTC).Aisen's team began their research in San Diego many years ago and teamed up with USC about four years ago. He's spent over 30 years trying to solve Alzheimer's mysteries and is leading the upcoming clinical trial.Aisen says the large-scale study is the culmination of decades of work from scientists worldwide."Our focus lately has been trying to alter the disease, prevent it, or significantly slow its progression. How should we do that? We think attacking amyloid early is the most promising approach," said Aisen. Researchers believe sticky amyloid deposits, which form on the brain later in life, start the Alzheimer's process. Aging, genetics, and lifestyle factors can all contribute to amyloid build-up.The worldwide clinical trial aims to target amyloid. A drug called BAN2401 will be delivered intravenously, designed to bind to the sticky amyloid. The binding neutralizes beta amyloid and helps "tag" it, so the immune system can recognize it and clear it from the brain. A previous phase 2 study showed that BAN2401 removes brain amyloid and possibly slows cognitive decline.They're seeking participants over 50 who are not yet showing symptoms of Alzheimer's but do have elevated amounts of amyloid on their brain. Researchers can determine that through a PET scan or spinal tap. "We think that the most promising approach of all is to take a vigorous attack on amyloid while the brain is still functioning normally. And we can see amyloid in people many years before they develop the symptoms of Alzheimer's."Investigators hope that by treating a patient with BAN2401 very early in the disease, before symptoms occur, it will significantly slow disease progression. "If we're successful, it will have a huge impact on human health," said Aisen. There will be 100 sites worldwide for the study, including major cities like San Diego and Los Angeles. Study participants will receive treatment for four years, given either the drug or a placebo. Results are expected in seven years, Aisen says. If you or a loved one wants to participate, learn more here.Screening will officially begin in May. 2438

SAN DIEGO (KGTV) - Catholic Charities San Diego is holding a workshop Saturday for young Dreamers affected by the DACA program uncertainty.Katia Ortiz is one of them. She said her parents brought her to the U.S. from Mexico when she was three. She said she has no recollection of where she was born.“It was really tough,” Ortiz said about feeling left out. She said she could not travel on class trips, she could not get a driver’s license and she could not apply for a college scholarship. She said DACA opened a lot of doors for her. “I got a job, and I got my license,” she explained. She also said she started attending college. Earlier this month, President Trump called to cut the program in March."It’s like you have everything and then it’s gone," Ortiz added.  "It’s tough thinking about, but I think what we all have to do is sit down and reflect."Frankly, at this time, I really don’t know what I would do."Catholic Charities San Diego helped about 700 people obtain DACA status, the group said. They said U.S. Citizenship and Immigration Services will continue processing pending initial application accepted as of Sept. 5, 2017 and pending renewal applications already filed. They went on to say USCIS will continue accepting renewal applications until Oct. 5, 2017 from applicants whose DACA expires between Sept. 5, 2017 and March 5, 2018. As it stands, all applications after Oct. 5, 2017 will be rejected.The group is holding free, bilingual information sessions, followed by one-on-one assessments.Those who qualify will be given an appointment to work with an accredited Catholic Charities staff member to complete their renewal application the next day.Scholarships are also available to cover the 5 application fee.Saturday's workshop was at St. Jude's Shrine of the West, 3785 Boston Ave.The next sessions will be:Tuesday, Sept. 19, at 6 p.m. at Holy Trinity Parish, 405 Ballard St., El Cajon.Wednesday, Sept. 20 at 6:30 p.m. at Mission San Luis Rey, 4050 Mission Ave., OceansideThursday, Sept. 28 at 6:30 p.m. at Our Lady of the Sacred Heart, 4177 Marlborough Ave., San Diego 2159

SAN DIEGO (KGTV) — Art, hot rods, and delicious brews are on tap for San Diego's weekend.If you're looking to exercise your creative sensibilities, try your hand at painting with "Beer and Bob" at Benchmark Brewing, where a session with Bob Ross will teach attendees how to create "Morning Mist." Or, visit the Oceanside Museum of Art Sunday for free admission during first Sunday.Cruisin' Grand returns to Escondido this weekend for some classic car action every Friday through the summertime. Head out and take a gander at some amazing feats of automotive ingenuity.RELATED: Things to do for free in San Diego CountyNorth Park will host a Festival of Beers, featuring 50 beers from the best breweries around, while there's sure to be some delicious brews at the San Marcos Spring Festival and Street Fair and Record Swap event at The Casbah.Here's a look at San Diego's weekend events:THURSDAYPainting with Beer and BobWhere: Benchmark Brewing Co.; Cost: Bust out your painting skills with a brew and a brush during Painting with Beer and Bob at Benchmark. Tickets get guests a beer and one-hour painting session recreating Bob Ross' "Morning Mist" portrait. Harry Potter and the Order of the Phoenix in concertWhere: Copley Symphony Hall; Cost: - The San Diego Symphony will take listeners along Harry Potter's journey through the wizarding world, as they provide the score to the film "Order of the Phoenix" as the movie is projected above the orchestra.FRIDAYCirque Du Soleil: VoltaWhere: Del Mar Fairgrounds; Cost: starting at (Thursday - Sunday) Experience the magic of Cirque Du Soleil under the bog top at Del Mar this weekend, as the energetic circus brings amazing feats using dance, high-flying maneuvers, and even BMX choreography.Cruisin' Grand EscondidoWhere: Grand Ave.; Cost: FreeEscondido's vintage auto show on the street returns every Friday from April 5 to Sept. 27, bringing out visitors, car enthusiasts and hundreds of historic cars. People watch, stop for a bite to eat, and enjoy a look at automotive ingenuity spanning Grand Ave.SATURDAYSouth Bay Earth DayWhere: Memorial Park; Cost: FreeThe South Bay's largest Earth Day event is will bring bicycling events, fix-it clinics, organic food, art exhibits, yoga, and much more fun to Memorial Park in celebration of Earth Day. The event will offer attendees tips and tricks for recycling and energy conservation as well.Vinyl Junkies Record SwapWhere: The Casbah; Cost: Fans of vinyl won't want to miss out on thousands of records up for sale during The Casbah's record swap this weekend. The 21+ event will feature free tote bags and pizza from Lefty's Chicago Pizzeria, live music, and some classic records to gush over — just in time for Record Store Day on April 13.North Park Festival of BeersWhere: Lafayette Hotel; Cost: - Unlimited tastings of more than 50 beers from some of the best breweries around will be featured at North Park's Festival of Beers. Proceeds from the event will benefit the San Diego Music Foundation, funding Taylor Guitars in local school music programs.SUNDAYJulian Gold Rush DaysWhere: Julian Farm; Cost: Admission is free, for adults(Saturday - Sunday) Experience the days of the gold rush in Julian with panning for gold, tomahawk throwing, archery, and more. Julian Farms will also host arts and crafts, a beer garden, and vendor booths to peruse, and free as well as priced activities.San Marcos Spring Festival and Street FairWhere: Via Vera Cruz, between San Marcos Blvd. & Grand Ave.; Cost: FreeCelebrate springtime in San Marcos with more than 250 artisan and craft vendors, a beer and wine garden, live performances and music, and carnival rides for kids during the city's massive Spring Festival and Street Fair.Oceanside Museum of Art Free First SundayWhere: Oceanside Museum of Art; Cost: FreeIt's the first Sunday of the month, which means free admission at the Oceanside Museum of Art. Head up north and check out exhibitions by the National Watercolor Society, artist Matthew Barnes, and a range of surrealism by San Diego artists. 4091

py the city of Berkeley in passing a law that allows activists to rescue animals in distress, like cows and chickens, from slaughterhouses.“It’s a big step to stop everyone to stop eating animals, so they’re not going quite that far,” says one demonstrator. “But what they’re trying to do is at least give those animals the right to be rescued.”San Diego Police arrived on scene and tried negotiating with the chained protesters to get them to leave. After 45 minutes, San Diego Fire-Rescue and other resources came in. The chains were cut and the protesters were taken into custody.“We want to make sure that everyone involved is safe and that no laws are broken,” says Capt. Mike Holden with SDPD. “In this case, we gave plenty of notice, and unfortunately, we had to effect for arrest.”Police say it is permissible to protest on the property but it is against the law to impede the flow of business.Shortly after the arrests, those who were not taken into custody held a rally outside City Hall. Organizers would like for San Diego leaders to implement rules locally that will endorse Rose’s law, which is an animal bill of rights.Rose’s law extends the rights of animals, like those found on a farm, to free, not owned; to not be exploited, abused or killed by humans; to have their rights represented in court; and the right to be free.City leaders are currently not taking up the issue. 1761

SAN DIEGO (KGTV) — Authorities are looking for an inmate who walked away from a San Diego rehabilitation facility.Steven Vargas, 53, was last seen at 10 a.m. Tuesday after leaving the San Diego's Male Community Reentry Program, according to the California Department of Corrections and Rehabilitation. Vargas had been given permission to leave the facility but didn't return when required.The facility allows eligible offenders with one year left to serve to do so in re-entry centers, providing them with rehabilitation services that assist them with substance use disorders, mental health care, employment, education, housing, and more. Officials said they were alerted that Vargas' electronic monitoring device had been tampered with just before noon Tuesday.Vargas was sentenced to four years in prison on May 6, 2019 for vehicle theft with prior vehicle related theft convictions and grand theft of a firearm. He was scheduled to be released on parole in June.Vargas is described as a Hispanic male, 6-feet tall, and weighs about 192 pounds. He was last seen wearing faded black jeans, black shoes, a blue shirt, and a charcoal grey sweater. He also has a long gray and white goatee.Anyone with information on Vargas' whereabouts is asked to call 911 immediately. 1276

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