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Today we honored the 100th Anniversary of the Ratification of the #19thAmendment by opening the #BuildingtheMovement youth art exhibit. I was moved talking to some of the young artists about the women suffrage movement & the inspiration behind their talented artwork! #BeBest pic.twitter.com/R6s9s1IKG4— Melania Trump (@FLOTUS) August 24, 2020 355

There is no question that 2020 has been a rough one for children, but it appears parents are doing what they can to atone for a rancid year.A survey of more than 1,000 parents commissioned by LendingTree found that 71% of parents say they plan to spend more on their children this Halloween to make up for other missed celebrations this year.This comes as many public health experts are encouraging parents to exercise caution this Halloween season as cases of the coronavirus continue to grow throughout the country. While children are generally at a low risk of having coronavirus complications, experts are concerned that children can spread the virus to those at a higher risk. "I think it is safe to say that 2020 has been a stressful year for most Americans. The toll that the coronavirus crisis has taken on the country's physical, emotional and financial health has been nothing short of staggering," said LendingTree's Chief Credit Analyst, Matt Schulz. "Between remote learning, social distancing measures, cancelled vacations, and fewer extracurriculars, parents and children alike have faced a lot of disappointment and unexpected difficulties in 2020. With the uncertainty around Halloween and Trick-or-Treating, it makes sense that parents want to go above and beyond to make the holiday season extra-special, for both their children and themselves."In addition to spending more this year, 79% percent of parents said they have spent more than they can afford on Halloween. Also, 65% say they have made purchases to show off on social media. 1563

There have been plenty of presidential elections when Nebraska hasn't cross too many minds. After all, it's a relatively conservative state where President Donald Trump won by 25 points in 2016. But this election, Democrats aren't forgetting about Nebraska, or more specifically, Omaha. DOING THINGS DIFFERENTLY Nebraska and Maine are the two states that award their Electoral College votes based off results in individual congressional districts. For instance, in 2008, John McCain and Barack Obama both received Electoral College votes from Nebraska. In Nebraska, two Electoral College votes goes to the statewide winner and one Electoral College vote goes to the winner in each of the state's three congressional districts. A total of five Electoral College votes is at stake. While Trump will again carry the statewide vote and two of the state's congressional districts, it is unclear what will happen in the 2nd Congressional District, which includes Omaha, Nebraska. Democrats believe there is a chance. "For whatever the reason, there are a lot of Democrats and independents saying they are going to vote for Biden," Bob Kerrey, the former Democratic governor and U.S. Senator from Nebraska, said. Republicans aren't conceding by any stretch, although they acknowledge it will be close. "We have more people than ever with boots on the ground knocking on doors," Theresa Thibodeau, chair of the Douglas County GOP, which includes Omaha, said. HOW IT COULD COME DOWN TO OMAHA If the election is close, there is a scenario where it all comes down to Omaha. If the projections in most states hold true -- and Trump wins the swing states of Florida, Georgia, North Carolina, Ohio, Pennsylvania & one congressional district in Maine and Joe Biden wins the battleground states of Arizona, Michigan, Nevada and Wisconsin -- how Omaha votes could decide the election. DEMOCRATS VS REPUBLICANS Of course Republicans in Nebraska don't particularly like the way in which their state allocates votes. "We should move our state back to a winner takes all," Thibodeau said. Former Senator Kerrey, obviously, disagrees. "We figured out how to do it right, to have a winner take all system basically throws out Republican and Democratic votes depending on where you live," Kerrey said. 2290

Too few new antibiotics are under development to combat the threat of multidrug-resistant infections, according to a new World Health Organization report published Tuesday. Adding to the concern: It is likely that the speed of increasing resistance will outpace the slow drug development process.As of May, a total of 51 antibiotics and 11 biologicals -- medical products often made from natural sources -- are being developed, the new report said."The idea is that biologicals could replace use of antibiotics, which could help in overcoming the resistance problem," Peter Beyer, an author of the report and senior adviser to the WHO's Department of Essential Medicines and Health Products, wrote in an email.Seemingly, this large number of potential new drugs should suffice, yet it is not nearly enough.First, just 33 of the antibiotics in the pipeline target priority pathogens. This year, the WHO published a list of a dozen "priority pathogens": 12 separate families of antibiotic-resistant bacteria that pose the greatest threat to human health.Among the priority pathogens is a drug-resistant tuberculosis, which kills about 250,000 people around the world each year, and a variety of multidrug resistant strains -- Acinetobacter, Pseudomonas and various Enterobacteriaceae -- which are responsible for infections in hospitals and nursing homes and among patients whose care requires ventilators and catheters.Of the 33 potential medicines for treating priority bug infections, only eight are innovative treatments. The other 25 are simple modifications of existing families of antibiotics. At best, then, the 25 will serve as short-term solutions since it is expected bacteria will quickly adapt to and resist these new (though somewhat familiar) drugs, according to the WHO."It is difficult to speculate why companies develop specific new medicines," Beyer noted. "But in general many new treatments do not necessarily constitute advances over existing treatments."TB infections require a combination of at least three antibiotics, according to the new report, yet only seven of the new TB medicines are even in clinical trials. Soon, there will be a serious lack of treatment options for this infection, the report warns.The same is true for gram-negative pathogens, which can cause severe, often deadly infections typically in hospitals and nursing homes.Gram-negative bacteria have more complex cell walls than gram-positive, explained Beyer. "In a nutshell, it is more complex to develop a novel antibiotic that can penetrate the complex gram-negative cell wall and stay inside the bacterium," he wrote.Finally, the WHO sees too few oral antibiotics being developed. These are necessary "to target the critical priority pathogens (and) be accessible in low- and middle-income countries," Beyer noted.To address the problem of developing new antibiotics, the WHO and the Drugs for Neglected Diseases Initiative set up the Global Antibiotic Research and Development Partnership. However, new drugs alone cannot combat the threat of antimicrobial resistance. The WHO is also working to improve infection prevention and control while developing guidance for the responsible use of antibiotics."Always seek medical advice before taking antibiotics and then always follow the advice of the health-care professional," Beyer noted.The new report is a "fantastic (and very useful!) summary" of the antibiotic situation, wrote Bill Hanage, an associate professor of epidemiology at Harvard T.H. Chan School of Public Health, in an email. Hanage, who has also published studies of antibiotic resistance, was not involved in the new report.Although the risk of getting a completely resistant infection is low in the United States, about 2 million people each year become infected with "resistant enough" bacteria that are harder to treat, Hanage said. And every year, more than 20,000 people die of these infections."More resistant infections don't just mean you or someone you care about is more likely to die from one, they also mean healthcare will get even more expensive," Hanage said. "Many of the procedures we take for granted in medicine, from cancer treatments to surgeries, depend on our ability to handle infections that happen in the course of treatment."The number of new drugs in development is simply not enough, he said."The great majority will not make it into the hands of doctors or your treatment," Hanage wrote. "As the report states, for drugs to be used in humans they have to pass 3 hurdles, the phase 1, 2 and 3 trials. Drugs entering that pipeline have just a 14% chance of getting all the way through to be used in humans." 4676

Though President Donald Trump remains hospitalized with a COVID-19 infection, it didn't stop him Monday morning from sending more than a dozen tweets — most of them in all caps — urging his supporters to vote for him on Election Day.Between 6:30 a.m. ET and 7:30 a.m. ET on Monday morning, Trump tweeted at least 17 times — most of which were completely in capital letters and included a policy position or administration goal followed by the call to "VOTE!"It was the most active the president has been on Twitter since his hospitalization on Friday. Typically a prolific user of Twitter, Trump has tweeted 14 times since he confirmed his COVID-19 diagnosis on Friday, many of those coming as retweets.Trump's tweetstorm comes as the nation is still mostly in the dark regarding his condition. Throughout the weekend, the president's doctors painted a relatively rosy picture regarding Trump's bout with the disease. However, his doctors declined to share when Trump's last negative test was, how high his fever reached and other important vitals. His doctors also reported Sunday multiple instances in which Trump's blood oxygen levels dropped significantly — something that was not mentioned the day before. The doctors' reports also contradict Saturday comments from White House Chief of Staff Mark Meadows, who called the president's condition on Friday "very concerning" and added that Sunday and Monday would be "critical" in his fight against the virus.Through several photos and videos released by the White House, Trump has attempted to maintain the appearance of wellness. Despite his infection with a highly contagious disease, Trump left the hospital briefly on Sunday for a ride in a Secret Service vehicle in front of the hospital to wave to his supporters. 1780

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