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SAN DIEGO (KGTV) — UC San Diego researchers are testing a technology that's been in development for more than a decade to fight the coronavirus.In lab experiments, "nanosponges" covered in human lung cell membranes and immune cell membranes were found to attract and neutralize the SARS-CoV-2 virus in cell culture, according to a UCSD release. This caused the virus to lose about 90% of infectivity, or its ability to hijack cells and reproduce.The tiny sponges are designed to impersonate and protect healthy cells by soaking up harmful pathogens and toxins, according to Liangfang Zhang, a nanoengineering professor at the UC San Diego Jacobs School of Engineering. RELATED: San Diego company's COVID-19 test gets emergency approvalFor example, the nanoparticle covered in membranes from cell types the virus is known to invade latch on to the virus. This prevent the virus from then entering an actual human cell."Traditionally, drug developers for infectious diseases dive deep on the details of the pathogen in order to find druggable targets. Our approach is different. We only need to know what the target cells are. And then we aim to protect the targets by creating biomimetic decoys," said Zhang.While Zhang has spent the last 10 years developing the technology, his lab turned to using the nano-particle to fight the coronavirus when the pandemic hit.RELATED: Scripps Research's antibodies study shows signs of success against coronavirusNow, the first data on the technology's ability to battle the virus is being released after testing by researchers at Boston University."Another interesting aspect of our approach is that even as SARS-CoV-2 mutates, as long as the virus can still invade the cells we are mimicking, our nanosponge approach should still work. I’m not sure this can be said for some of the vaccines and therapeutics that are currently being developed," said Zhang.UCSD researchers will test the nanosponges’ effectiveness in animal models in the next few months and are moving as fast as possible to eventually test the technology in humans. RELATED: Startup creates mobile COVID-19 testing clinic on wheelsNanosponges have a massive amount of testing ahead before they make it to human tests, Zhang said."I see potential for a preventive treatment, for a therapeutic that could be given early because once the nanosponges get in the lung, they can stay in the lung for some time," Zhang said. "If a virus comes, it could be blocked if there are nanosponges waiting for it."(Read more about the study and nanosponges here.) 2562

SAN DIEGO (KGTV) — Two people escaped uninjured after a sailboat crashed into an Ocean Beach jetty, before the vessel itself was crushed by high surf.The 25-foot long boat collided into the North Channel jetty in Ocean Beach with the two individuals on board, according to San Diego Fire-Rescue Department spokeswoman Monica Mu?oz. San Diego Lifeguards used a personal water craft to reach the vessel and safely pull the two individuals after they were forced to jump from the boat. The boat was attempting to leave the jetty area when a large wave forced them to pull a U-turn. SAN DIEGO FORECAST: Wednesday's rains to strengthen heading into ThursdayWind caught the sails and instead sent the vessel back into the jetty, according to witnesses at the scene.Those two people were uninjured in the wreck though the sailboat was crushed by high surf and sunk within the channel's entrance, according to Mu?oz.The boat's owner is now responsible for making arrangements to tow the boat from the channel.RELATED: Where to get free sandbags to protect your home from floodingA storm system forecasted for San Diego County has brought high sets to local beaches Wednesday. High surf forced the Ocean Beach Pier to close and lifeguards to ask swimmers to stay out of the water, as waves could be seen crashing against the pier. 1329

San Diego (KGTV)- A music teacher at Grossmont High School reached out to the community after students were in need of guitars for the upcoming school year. The students will be practicing distance learning.Music teacher Jeremy Cook says the support has been overwhelming.“The response from the community has been absolutely amazing. I’ve met so many people. I’ve driven across the county picking up the guitars,” says Cooke.Cooke has received 117 guitars for students to practice.“Last year we had upwards of 120 guitar students total,” says Cooke. “There’s a hope to be able to offer guitars to students who aren’t able to take the class.”A couple of weeks ago, Cooke went to pick up a donation from a woman named Pam Anderson in Mission Hills.“I took it back to my car and popped it open. I was flabbergasted at what was inside. It was a 1969 Fender Telecaster.”These guitars range from ,000 to ,000. Cooke says he had to let Anderson know its value.“She said that she appreciated the honesty, and she still wanted to donate the guitar to the school,” says Cooke. “It was her husband’s who passed away. She said she knew he would want the same thing.”The guitar will be used for student performances and in the newly renovated music room when students are allowed back on campus.Cooke says he appreciates all of the donations. As a thank you to Anderson, the teacher has set up a GoFund Me page to help her during the pandemic.Cooke says there is still a need for guitars for the upcoming school year. If you would like to donate, email Cooke at jcooke@guhsd.net or message him on Instagram @covidguitars. 1620

SAN DIEGO (KGTV) -- Two San Diego beaches have made TripAdvisor’s list of top 25 beaches in 2018. Pacific Beach came in at number 20 on the list followed by La Jolla Shores Park at 22.62 percent of people who rated Pacific Beach on the site rated it as excellent while 64 percent of people rated La Jolla Shores as excellent.RELATED: AAA's top rated restaurants, hotels in San Diego CountyThe beach at the top of this year’s list is Clearwater Beach in Florida. Check out TripAdvisor's list of top ten beaches in the U.S.: 550

SAN DIEGO (KGTV) — Wasting away in "Margaritaville" will soon be an option much closer to home.The site of downtown's Solamar Hotel will be renovated to make way for the Margaritaville Hotel, set to open in 2021. The hotel will include 235 guest rooms and plenty of signature Margaritaville food and drink concepts for visitors.The renovation and full conversion of the hotel is expected to cost about million.RELATED: Margaritaville Island Resort coming to San Diego“We are excited to announce our second hotel in affiliation with Margaritaville in San Diego,” said Jon Bortz, CEO of Pebblebrook Hotel Trust. “The downtown location in San Diego’s famed Gaslamp Quarter will provide convention goers, leisure guests and corporate travelers a unique experience in very close proximity to the city’s dining, entertainment and retail venues ... The Gaslamp Quarter property will be a terrific complement to our Margaritaville Island Resort San Diego which was announced last year.”By 2021, Paradise Point Resort & Spa on Vacation Isle Park in Mission Bay will also see a similar transformation into the Margaritaville Island Beach Resort. The resort will feature 462 casita-style guest rooms, themed-food and drinks, and family-friendly amenities.The Solamar Hotel was purchased in 2018 by Pebblebrook Hotel Trust. The hotel is located on 6th Ave., near Gaslamp District dining and entertainment and blocks from Petco Park and the convention center — adding to its appeal for its new image.“We are thrilled to collaborate on our second hotel with Pebblebrook, a team that values quality design, creativity and engaging guest experiences,” said John Cohlan, CEO of Margaritaville. “The iconic Gaslamp District, with its dynamic nightlife, signature events and proximity to the home of the Padres, fits perfectly with the Margaritaville lifestyle." 1859