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Jessop’s Clock, a historical San Diego icon for more than 100 years, is being removed from Horton Plaza.No word yet on where it’s going.@10News pic.twitter.com/HpQkGn8pZ3— Amanda Brandeis (@10NewsBrandeis) April 2, 2019 233

Johnson & Johnson announced it has paused its coronavirus vaccine trials on Monday following an “unexplained illness” among one of its participants.Johnson & Johnson stressed that adverse events during trials are expected, and a pause gives researchers an opportunity to review all of the medical information before moving forward with the trial. Johnson & Johnson added that it’s not always immediately known if the affected person received a placebo or a study treatment.Among the trials paused was Johnson & Johnson’s multi-country “ENSEMBLE” vaccine, which entered Phase 3 testing in September. Johnson & Johnson said last month that its goal was to seek an emergency use authorization approval in early 2021.The FDA noted that a vaccine candidate must be at least 50% effective to receive emergency use authorization. Vaccine candidates should include a median follow-up duration of at least two months after completion of the full vaccination regimen to help provide adequate information to assess a vaccine’s risk-benefit.According to the FDA, a typical Phase 3 trial would take one to three years.“NIH is committed to supporting several Phase 3 vaccine trials to increase the odds that one or more will be effective in preventing COVID-19 and put us on the road to recovery from this devastating pandemic,” said NIH Director Francis S. Collins, M.D., Ph.D. “We also know that preventing this disease could require multiple vaccines and we’re investing in those that we believe have the greatest potential for success.” 1554

Kentucky Speaker of the House Jeff Hoover resigned from his position Sunday amid sexual harassment allegations, saying he had made "mistakes."Hoover, who The Courier-Journal newspaper in Louisville reported had secretly settled a sexual harassment allegation by a woman on his legislative staff, did not resign as a state representative, however, and has denied all allegations."I did make mistakes, in that I engaged in inappropriate text messages," the Republican lawmaker said at a press conference announcing his decision. "I engaged in banter that was consensual, yet make no mistake, it was wrong on my part to do that. And for that I am truly sorry."The Courier-Journal was the first to report Hoover's settlement last week, citing sources with direct knowledge of the matter. The settlement involved three other Republican state representatives and Hoover's chief of staff, the newspaper reported.Hoover and his accuser, whom the Courier-Journal has not identified because she says she was sexually harassed, declined to comment, as did a lawyer for the woman, the newspaper said.Hoover asked for the public's forgiveness in a tearful statement on Sunday, saying, "To say that the past few weeks and days have been trying and difficult for me and my family would be an understatement."Kentucky's House speaker pro tempore, Republican David Osborne, said in a statement that he will be assuming operational control of the chamber as acting speaker.Hoover's resignation comes a day after Kentucky Gov. Matt Bevin, also a Republican, called for "the immediate resignation of every individual who has settled a sexual harassment case, who is party to trying to hide this type of behavior."In a press conference Saturday, Bevin drew a "clear line in the sand for every elected official in Kentucky. These actions that have been alleged, not denied, and increasingly corroborated, and that are increasing in specificity and in number, were not isolated to a single person, or a single event, but involved multiple events and multiple people.""They know who they are, some have been named," Bevin said. "I would simply say this: For the sake of themselves, for the sake of their families and for the sake of Kentucky, they should resign. Period. The people of Kentucky deserve better than the type of shenanigans that have gone on for far too long in this town.""I expect the immediate resignation of everyone named," Bevin concluded.Hours after Bevin's speech, Hoover issued a statement that stopped short of confirming the Courier-Journal report."I am disappointed that our Governor in his press conference Saturday afternoon would call not only for my resignation but the resignation of other individuals who have no involvement in this matter," he said. "The governor has yet to ask our side of the story. He and I have not spoken since the story broke, and I did not receive a courtesy call from him before his grandstanding today. Instead, he has accepted as fact only, one side of the story.""In effect, the governor seeks to be judge, jury, and executioner without hearing the evidence," Hoover said, adding then that he had no plans to resign, and was "more resolved than ever to continue my work as speaker thru the 2018 session." 3264

Joe Biden took questions from voters in Pennsylvania on Thursday on ABC as President Donald Trump did the same on NBC in Florida at the same time.Pennsylvania is considered one of the most important battleground states in this year’s election.CoronavirusBiden left open the possibility of mandating a coronavirus vaccine nationally.“It depends on the state of the nature of the vaccine when it comes out and how’s it being distributed,” Biden said, adding that he will judge a mandate based on the efficacy of a vaccine.Biden was then pressed on how to enforce a vaccine mandate.“You couldn’t enforce it,” Biden added.Biden criticized Trump for his initial response to the virus, pointing to an interview with Bob Woodward, when Trump acknowledged he did not want to panic Americans.“The president was informed how dangerous this virus was already way back in February,” Biden said.“He said he didn’t tell Americans to panic. He panicked. He didn’t say a word to anybody,” Biden added.Biden said that the federal government could play a key role in helping children get back to school amid the pandemic."We need more teachers, smaller pods, we need ventilation systems changed,” Biden said. “There are a lot of things we need now. I laid them out in detail… We did lay out exactly what needed to be done.”TaxesBiden said he vowed not to raise taxes on those making below 0,000 per year even though he would roll back the tax cuts Republicans signed back in 2017. Biden said much of the over trillion in tax cuts went to the wealthy. Biden said he would increase taxes on wealthier Americans.“When I said the Trump tax cuts, about .3 trillion of the trillion in his tax cuts went to the top one tenth of 1%,” Biden said. “That’s what I’m talking about eliminating. Not all the tax cuts that are out there.”PolicingJoe Biden was asked if he still supports the Crime Bill he signed in 1993. Biden said he did not, and he placed the blame on states for using federal funds to build more prisons.“The crime bill itself did not have mandatory sentences, except for two things," Biden said. "It had three strikes and you’re out, which I voted against in the crime bill, but it had a lot of things in it that turned out to be both bad and good,” he said, before noting his work on the Violence Against Women Act and an assault weapons ban."While some on the liberal wing are calling on defunding police departments, Biden said he opposes it. He added he believes that more officers can make communities safer, “If they’re involved in community policing and not jump squads.”Supreme Court Following the nomination of Amy Coney Barrett, some Democrats have called on a potential Biden presidency to add Supreme Court members. Biden said he is opposed to adding members to the Supreme Court, but would not rule out adding his appointees to the court.Barrett will likely be confirmed by the US Senate next week, giving Republican-appointed justices a 6-3 advantage in the high court."I have not been a fan of court packing because it can generate – whoever wins, it keeps moving in a way that is inconsistent with what is going to be manageable,” Biden said. “I am not a fan, but it depends on how this turns out.”Biden said a fast confirmation of Barrett could sway him.“It depends on how much they rush it,” Biden said.Biden criticized the Senate for taking up Barrett’s nomination, but not working on a stimulus bill.“They have no time to deal with that but they have time to rush this through,” Biden said.Biden he would take a definitive stance on adding Supreme Court members by Election Day, depending on how the Barrett nomination goes. 3651

Jimmy Kimmel didn't pull any punches when it came to the Senate's new health care bill and U.S. Sen. Bill Cassidy, saying that Cassidy lied "right to my face.""A few months ago after my son had open heart surgery, which was something I spoke about on the air, a politician, a Senator named Bill Cassidy from Louisiana was on my show and he wasn't very honest," Kimmel said opening Tuesday night's show.Kimmel then explained how Cassidy came up with what the senator called the "Jimmy Kimmel Test," which according to the host was a test that said that "No family should be denied medical care, emergency or otherwise because they can't afford it." 655

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