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Hurricane Dorian has intensified to a dangerous Category 3 storm on Friday according to the National Hurricane Center.Dorian is now packing 125 mph winds in the western Atlantic Ocean.The National Hurricane Center said Dorian "poses a significant threat to Florida and the Northwestern Bahamas," and is now forecast to make landfall on late Monday or early Tuesday as a possible Category 4 storm. A hurricane warning was issued for parts of the Bahama Islands Friday evenings.The 5 p.m. forecast has the storm staying a Category 4 until landfall along the Florida east coast early Tuesday morning.Weather models show and estimate between 12 to 15 inches of rain, or more, between Monday morning and Wednesday morning in some locations.Dorian is likely to remain an extremely dangerous hurricane while it moves near the northwestern Bahamas and approaches the Florida peninsula through the weekend.The storm is moving toward the west-northwest near 10 mph and this general motion is expected to continue through Friday.A slower west-northwestward to westward motion should begin Friday night and continue into early next week.On this track, the core of Dorian should move over the Atlantic well north of the southeastern and central Bahamas Friday and Saturday, be near or over the northwestern Bahamas on Sunday, and be near the Florida peninsula late Monday.Hurricane force winds extend outward up to 30 miles from the center and tropical storm force winds extend outward up to 115 miles.On Thursday, 1514

Former White House communications director Hope Hicks told lawmakers Wednesday that she had "never been asked to lie about matters of substance or consequence," contending that "white lies" she had told on behalf of President Donald Trump were about small matters, such as his availability.The comments are part of 327

HOUSTON, Texas — A federal grand jury has handed down a 206-count indictment in a large-scale marriage fraud scheme, according to U.S. Immigration and Customs Enforcement.Homeland Security Investigations Houston, ICE and U.S. Citizenship and Immigration Services investigated the case in which 96 people have been federally charged. The indictment was handed down April 30.A suspected criminal organization created sham marriages to illegally obtain admission and grant status for illegal immigrants in the United States, ICE announced.The indictment says Ashley Yen Nguyen, known as Duyen, 53, of Houston, headed the Southwest Houston-based organization and had associates operating throughout Texas and the Republic of Vietnam.“Marriage fraud is a serious crime,” 778

First came a high fever, drenching sweats and muscle aches. Then, almost a month later, a weird numbness that spread down the right side of her body.Darlene Gildersleeve thought she had recovered from COVID-19. Doctors said she just needed rest. And for several days, no one suspected her worsening symptoms were related — until a May 4 video call, when her physician heard her slurred speech and consulted a specialist.“You’ve had two strokes,” a neurologist told her at the hospital. The Hopkinton, New Hampshire, mother of three is only 43.Blood clots that can cause strokes, heart attacks and dangerous blockages in the legs and lungs are increasingly being found in COVID-19 patients, including some children. Even tiny clots that can damage tissue throughout the body have been seen in hospitalized patients and in autopsies, confounding doctors’ understanding of what was once considered mainly a respiratory infection.“I have to be humble and say I don’t know what’s going on there, but boy we need to find that out because unless you know what the pathogenic (disease-causing) mechanism is, it’s going to be tough to do intervention,” Dr. Anthony Fauci, the nation’s top infectious disease expert, remarked during a medical journal interview last month.Doctors and scientists at dozens of hospitals and universities around the globe are seeking answers while trying to measure virus patients’ risks for clots and testing drugs to treat or prevent them.Gildersleeve said health authorities “need to put out an urgent warning about strokes” and coronavirus. Not knowing the possible link “made me doubt myself” when symptoms appeared, she said.Some conditions that make some COVID-19 patients vulnerable to severe complications, including obesity and diabetes, can increase clot risks. But many authorities believe how the virus attacks and the way the body responds both play a role.“COVID-19 is the most thrombotic (clot-producing) disease we’ve ever seen in our lifetime,” said Dr. Alex Spyropoulos, a clot specialist and professor at Feinstein Institutes for Medical Research in Manhasset, New York.Clotting has been seen in other coronavirus infections, including SARS, but on a much smaller scale, he said.Scientists believe the coronavirus enters the body through enzyme-receptors found throughout the body, including in cells lining the inside of blood vessels. Some theorize that it may promote clotting by somehow injuring those vessels as it spreads. That injury may cause a severe immune response as the body tries to fight the infection, resulting in inflammation that may also damage vessels and promote clotting, said Dr. Valentin Fuster, director of Mount Sinai Heart hospital in New York.It’s unclear how many COVID-19 patients develop clots. Studies from China, Europe and the United States suggest rates ranging from 3% to 70% of hospitalized COVID-19 patients; more rigorous research is needed to determine the true prevalence, the National Institutes of Health says.Prevalence in patients with mild disease is unknown and the agency says there isn’t enough evidence to recommend routine clot screening for all virus patients without clotting symptoms, which may include swelling, pain or reddish discoloring in an arm or leg.Some hospitals have found 40% of deaths in COVID-19 patients are from blood clots. Spyropoulos said that’s been true at his 23-hospital system in the New York City area, Northwell Health, which has treated over 11,000 COVID-19 patients.Cases there have dropped by almost half in the past month, allowing more time for research before an expected second and maybe third wave of infections, he said, adding: “We’re racing against time to answer the key clinical questions.”Patients hospitalized with any severe illness face increased risks for clots, partly from being bedridden and inactive. They commonly receive blood-thinning drugs for prevention. Some doctors are trying higher-than-usual doses for prevention in hospitalized coronavirus patients.A few have used powerful clot-busting medicines typically used to treat strokes, with mixed results. In guidance issued May 12, the NIH said more research is needed to show whether that approach has any benefits.Fuster was involved in preliminary research on nearly 2,800 COVID-19 patients at five hospitals in the Mount Sinai system. A look at their outcomes suggests slightly better survival chances for virus patients on ventilators who received blood thinners than among those who didn’t. Although the results are not conclusive, all COVID-19 patients at Mount Sinai receive blood thinners for clot prevention unless they are at risk for bleeding, a potential side effect, Fuster said.Some COVID-19 patients, like Gildersleeve, develop dangerous clots when their infections seem to have subsided, Spyropoulos said. Patients treated at Northwell for severe disease are sent home with a once-a-day blood thinner and a soon to be published study will detail their experiences. Spyropoulos has been a paid consultant to Janssen Pharmaceuticals, makers of Xarelto, the drug’s brand name.In addition, Northwell is taking part in a multi-center study that will test using blood thinners for clot prevention in COVID-19 patients not sick enough to require hospitalization.In a small study published May 15, University of Colorado doctors found that combined scores on two tests measuring clotting markers in the blood can help determine which patients will develop large dangerous clots. One test measures a protein fragment called D-dimer, a remnant of dissolved clots. High levels sometimes indicate dangerous clots that form deep in leg veins and travel to the lungs or other organs.Dr. Behnood Bikdeli of Columbia University’s Irving Medical Center, said D-dimer levels in many of his COVID-19 patients have been alarmingly high, as much as 50 times higher than normal.Concerns about blood clots in COVID-19 patients prompted a recent 30-page consensus statement from an international group of physicians and researchers. Bikdeli is the lead author.It says that testing to find clots that require treatment includes X-rays or ultrasound exams, but poses a risk for health care workers because the virus is so contagious. Bikdeli said he fears when protective gear was more scarce, some dangerous clots were undiagnosed and untreated.Social distancing may make people more sedentary and more vulnerable to clots, particularly older adults, so doctors should encourage activity or exercises that can be done in the home as a preventive measure, the statement says.Warnell Vega got that advice after collapsing at home April 19 from a large clot blocking a lung artery. Doctors at Mount Sinai Morningside think it was coronavirus-related. Vega, 33, a lunch maker for New York City school children, spent a week in intensive care on oxygen and blood thinners, which he’s been told to continue taking for three months.“I just have to watch out for any bleeding, and have to be careful not to cut myself,” Vega said.Gildersleeve, the New Hampshire stroke patient, was also sent home with a blood thinner. She gets physical therapy to improve strength and balance. She still has some numbness and vision problems that mean driving is out, for now.Doctors are unable to predict when or whether she’ll regain all her abilities.”I’m trying to remain positive about recovering,” she said. ’’I just have to be patient and listen to my body and not push too hard.”___Follow AP Medical Writer Lindsey Tanner at @LindseyTanner.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’ 7639

Having children will make you happier than staying childless, according to a new study, but not until later in life, when they have flown the nest.A team of researchers at Heidelberg University in Germany found that parents tend to be happier than non-parents in old age, but this only holds if their kids have moved out.Previous research has suggested that parenthood, social networks and marital status affect the well-being and mental health of older people, and this latest study looks at the effects of family status.Scientists asked 55,000 people age 50 and over from 16 European countries about their mental well-being, and results suggest "the positive aspects of parenthood dominate when getting older."One of the biggest factors is that children become a form of social support, and the researchers point out that social support networks are associated with greater happiness and less loneliness and can act as a buffer against stressful events."The results suggest that the finding of a negative link between children and well-being and mental health may not generalize to older people whose children have often left home already," the study says."As stress associated with balancing the competing demands of childcare, work and personal life decreases, once people get older and their children leave (home), the importance of children as caregivers and social contacts might prevail."However, children who still live at home are shown to have a negative effect on well-being.Christoph Becker, who formed part of the research team, told CNN that having a social network corresponds to greater life satisfaction, but that doesn't have to come from children.Older people without children could get similar benefits from other close social connections with whom they can share issues and problems, he added.Becker told CNN there are plans to track happiness for the same people over multiple years to study how well being evolves as people get older."Literature has suggested that there might be U-shaped connection between age and happiness: people become less happy in middle age, but more happy in older age," said Becker."We want to test if we find a similar relationship in our data, depending again on parenthood and social networks."Previous research on the subject has been mixed.A report by Princeton University and Stony Brook University published in the Proceedings of the National Academy of Sciences found "very little difference" between the life satisfaction of parents and people without children, once other factors -- such as income, education, religion and health -- were factored out, said Arthur Stone, one of the study's co-authors.Another study, by the Open University in England, found childless couples were happier with their relationships and their partners than parents were, and were doing more work on their relationships than parenting couples. 2895